Results 81 to 90 of about 7,041 (257)

Determination of the shelf life of the API morpholinium 2-((4-(2-methoxyphenyl)-5-(4-pyridyl)-4H-1,2,4-triazol-3-yl)thio)acetate

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki
This study determined the shelf life of the active pharmaceutical ingredient (API) morpholinium 2-(4-(2-methoxyphenyl)-5-(4-pyridyl)-4H-1,2,4-triazol-3-yl)thio)acetate by determining its quantitative storage characteristics. Aim.
A. H. Kaplaushenko, S. O. Vasyuk, A. I. Avramenko , M. Zh. Koichev   +3 more
doaj   +1 more source

Multimodal Learning with Rashomon Analysis for Battery Discharge Capacity Prediction

Advanced Intelligent Discovery, EarlyView.
Multimodal fusion integrates composition, crystal‐structure, and radial‐distribution descriptors to predict battery discharge capacity. Rashomon analysis across near‐optimal models reveals that explanatory variation is structured rather than arbitrary, separating stable mechanistic signals from model‐contingent attributions and providing a more ...
Jue Gong, Lejia Wang, Tianqing Zhu, Keith Butler, Sichao Li   +4 more
wiley   +1 more source

Nanostructured Deep Eutectic Systems in Healthcare: From Bioactive Solvents to Intelligent Biointerfaces, Wearables, and AI‐Driven Design

Advanced NanoBiomed Research, EarlyView.
Beyond the green solvent paradigm, this review redefines Deep Eutectic Systems (DES) as programmable supramolecular nanoassemblies. We survey their biomedical convergence: stabilizing thermolabile mRNA to enable cold chain‐free logistics, reshaping transdermal microneedle delivery, enabling long‐term wearables via eutectogels, and utilizing Generative ...
Jeesu Moon, Min Seo Kim, Jae‐Seung Lee
wiley   +1 more source

Ibuprofen-Amino Acids Co-Crystal Screening Via Co-Grinding Methods

MATEC Web of Conferences, 2016
The importance of pharmaceutical co-crystals now has been recognized in order to improve the research and development in pharmaceutical industries. Low solubility of active pharmaceutical ingredient (API) has led to the growth of new pharmaceutical co ...
Othman Muhamad Fitri, Jamburi Norasikin, Anuar Nornizar, Abd. Rahim Syarifah, Rohalim Nurul Hazwani   +4 more
doaj   +1 more source

Impurity Profiling of Active Pharmaceutical Ingredients (APIs)

Impurity profiling plays a critical role in ensuring the safety, efficacy, and quality of Active Pharmaceutical Ingredients (APIs). Pharmaceutical impurities may arise from starting materials, intermediates, by-products, degradation pathways, or contamination during manufacturing and storage.
openaire   +2 more sources

Co-Crystal Screening of Diclofenac

Pharmaceutics, 2011
In the pharmaceutical industry, co-crystals are becoming increasingly valuable as crystalline solids that can offer altered/improved physical properties of an active pharmaceutical ingredient (API) without changing its chemical identity or biological ...
John Desper, Christer B. Aakeröy, Angela B. Grommet   +2 more
doaj   +1 more source

Design Considerations for Polymer–Deep Eutectic Solvent Hybrid Systems for Transdermal Drug Delivery

Journal of Applied Polymer Science, EarlyView.
Deep eutectic solvents (DESs) act as tunable, green excipients that modulate polymer structure–property relationships to enhance drug solubility, skin permeation, stability, and controlled release. Through hydrogen‐bond interactions, DES–polymer hybrid systems enable improved transdermal performance, offering a rational, design‐driven platform for ...
Madhavi Kailas Kapale, Madhur Kulkarni, Pranav J. Shah, Furqan A. Maulvi   +3 more
wiley   +1 more source

Application of flow chemistry in process development of active pharmaceutical ingredients (APIs) [PDF]

, 2019
The concept of "flow chemistry" defines a general range of chemical processes that occur in a continuous flowing stream, conventionally taking place in a reactor zone. The application of flow chemistry relies on the concept of pumping reagents using many reactors types to perform specific reactions.
Mastelić Samardžić, Zrinka, Wittine, Ozren, Vusak, Vitomir, Mihovilović, Moris   +3 more
openaire   +2 more sources

Impact of API (Active Pharmaceutical Ingredient) Source Selection on Generic Drug Products [PDF]

Pharmaceutical Regulatory Affairs: Open Access, 2015
The pharmaceutical industry is emerging as a significant industrial sector with tremendous potential for providing innovative drugs to treat life-threatening diseases as well as for providing economical generic alternatives of supreme quality. Hence this sector is not only responsible to provide the much desired boost to the health of the society ...
openaire   +1 more source

Context‐centric proactive information delivery for Knowledge Work support: Opportunities, challenges, and directions. An Annual Review of Information Science and Technology (ARIST) paper

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Context‐centric proactive information delivery (PID) is a relatively underexplored domain within recommender systems (RS) aimed at enhancing Knowledge Workers' productivity by proactively providing relevant information during digital tasks.
Mahta Bakhshizadeh, Christian Jilek, Markus Schröder, Heiko Maus, Andreas Dengel   +4 more
wiley   +1 more source