Results 31 to 40 of about 1,638,765 (242)

Tibetan medicine salidroside improves host anti-mycobacterial response by boosting inflammatory cytokine production in zebrafish

Frontiers in Pharmacology, 2022
The treatment for tuberculosis (TB), especially multidrug-resistant TB (MDR-TB), has a prolonged cycle which can last up to a year. This is partially due to the lack of effective therapies.
Shumei He, Hongyan Fan, Hongyan Fan, Bin Sun, Meipan Yang, Hongxu Liu, Hongxu Liu, Jianwei Yang, Jianwei Yang, Jianxin Liu, Jianxin Liu, Sizhu Luo, Sizhu Luo, Zihan Chen, Zihan Chen, Jing Zhou, Jing Zhou, Lu Xia, Shulin Zhang, Shulin Zhang, Bo Yan   +20 more
doaj   +1 more source

Large Photospheric Doppler Shift in Solar Active Region 12673. I. Field-aligned Flows

The Astrophysical Journal, 2023
Delta ( δ ) sunspots sometimes host fast photospheric flows along the central magnetic polarity inversion line (PIL). Here we study the strong Doppler shift signature in the central penumbral light bridge of solar active region NOAA 12673.
Jiayi Liu, Xudong Sun, Peter W. Schuck, Sarah A. Jaeggli, Brian T. Welsch, C. Quintero Noda   +5 more
doaj   +1 more source

Confinedness of an X3.1-class Solar Flare Occurred in NOAA 12192: Analysis from Multi-instrument Observations

The Astrophysical Journal, 2023
The nonassociation of coronal mass ejections with high energetic flares is sparse. For this reason, the magnetic conditions required for the confinedness of major flares is a topic of active research.
N. Vasantharaju, F. Zuccarello, F. Ferrente, S. L. Guglielmino   +3 more
doaj   +1 more source

In silico testing of C9H12ClNO2 and C6H5Cl2NO as derivatives of acetaminophen using molecular docking method

Notulae Scientia Biologicae
Paracetamol, a commonly used analgesic and antipyretic medication, is well-known for its ability to relieve pain and reduce temperature. However, there is a constant push to improve its therapeutic efficacy, especially towards increasing its oral ...
Juan LORELL, Kathy IVANA, Joselyn P.W. TANOTO, Michael MICHAEL, Sarah JESCIKA, Nicolaas R.P. GAUTAMA, Olivia TJOA, Keisha ALINA, Arli A. PARIKESIT, Fandi SUTANTO   +9 more
doaj   +1 more source

Quantum-Well-Embedded InGaN Quantum Dot Vertical-Cavity Surface-Emitting Laser and Its Photoelectric Performance

Photonics
An electrically injected vertical-cavity surface-emitting laser (VCSEL) with quantum-well-embedded InGaN quantum dots (QDs) as the active region was designed.
Zinan Hua, Hailiang Dong, Zhigang Jia, Wei Jia, Lin Shang, Bingshe Xu   +5 more
doaj   +1 more source

Structure Design of UVA VCSEL for High Wall Plug Efficiency and Low Threshold Current

Photonics
Vertical-cavity surface emitting lasers in UVA band (UVA VCSELs) operating at a central wavelength of 395 nm are designed by employing PICS3D(2021) software.
Bing An, Yukun Wang, Yachao Wang, Zhijie Zou, Yang Mei, Hao Long, Zhiwei Zheng, Baoping Zhang   +7 more
doaj   +1 more source

Solar flare forecasting using morphological properties of sunspot groups

Journal of Space Weather and Space Climate, 2019
We describe a new tool developed for solar flare forecasting on the base of some sunspot group properties. Assuming that the flare frequency follows the Poisson statistics, this tool uses a database containing the morphological characteristics of the ...
Falco Mariachiara, Costa Pierfrancesco, Romano Paolo   +2 more
doaj   +1 more source

Arachidonoylcholine and Other Unsaturated Long-Chain Acylcholines Are Endogenous Modulators of the Acetylcholine Signaling System

Biomolecules, 2020
Cholines acylated with unsaturated fatty acids are a recently discovered family of endogenous lipids. However, the data on the biological activity of acylcholines remain very limited.
Mikhail G. Akimov, Denis S. Kudryavtsev, Elena V. Kryukova, Elena V. Fomina-Ageeva, Stanislav S. Zakharov, Natalia M. Gretskaya, Galina N. Zinchenko, Igor V. Serkov, Galina F. Makhaeva, Natalia P. Boltneva, Nadezhda V. Kovaleva, Olga G. Serebryakova, Sofya V. Lushchekina, Victor A. Palikov, Yulia Palikova, Igor A. Dyachenko, Igor E. Kasheverov, Victor I. Tsetlin, Vladimir V. Bezuglov   +18 more
doaj   +1 more source

The Role of “Adult‐Onset” Cancer Predisposition Genes in Pediatric Cancer: A Comprehensive Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Current literature estimates that 10% of pediatric cancers are caused by pathogenic or likely pathogenic (P/LP) germline variants in cancer predisposition genes (CPGs). Variants in CPGs thought to increase cancer risk exclusively during adulthood are referred to as “adult‐onset” CPGs (aoCPGs).
Maria Rozo, Miriam A. Bornhorst, Angela J. Waanders, Sara Zarnegar‐Lumley, Ashwin Lakshman Koppayi, Lucy A. Godley   +5 more
wiley   +1 more source

Clinical, Histopathological, and Molecular Characterization of Pediatric MN1::ZNF341‐Associated Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT A lethal round‐cell malignancy with an MN1::ZNF341 fusion has recently been reported in three infants. Here, we describe four further tumors, three in newborns (including monozygotic twins), and one in an adolescent. Detailed clinical, radiological, and histopathological data differentiate these tumors from their main mimics, neuroblastoma and
Thomas R. W. Oliver, Dyanne Rampling, Barbara Walkowiak, Nathaniel D. Anderson, Manas Dave, Henry Lee‐Six, Sadie Baskind, Pooja Balasubramanian, Glenn Anderson, Conor Parks, Toochi Ogbonnah, Emilia R. Robertson, Simon Hannam, Rohan Verma, John C. Achermann, Liina Palm, Neil Sebire, Thomas Jacques, Tom Watson, Carryl Dryden, Karin Straathof, Mette Jorgensen, Olga Slater, Sam Behjati, Sarita Depani, J. Ciaran Hutchinson   +25 more
wiley   +1 more source