Results 71 to 80 of about 8,578,817 (287)
Objectives: This study was performed to simultaneously improve the solubility, permeability, and pharmacological activity of decoquinate (DQ). Methods: A ternary DQ solid dispersion with hydroxypropyl-β-cyclodextrin (HP-β-CD) and tea saponin (TS) was ...
Wei Wei, Qihong Zhang, Weike Su
doaj +1 more source
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
BACKGROUND: Physical activity (PA) promotion is one of the most important factors in prevention of non-infectious civilization diseases. Other factors that may affect PA (economical, environmental, socio-cultural, etc.) are intensively monitored in ...
Dana Feltlová +5 more
doaj +1 more source
Transportation Development Division, Active Transportation Section
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on March 9, 2015).Mode of ...
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Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Title from caption.; Caption note: Initials of Black, the leader of the prospecting team unclear, possibly A.C.; Part of collection: Photographs.; Exhibited: "Travellers Art", National Library of Australia, 12 June 2003-21 September 2003; Exhibited ...
Millar, Roy, active 1884-1900.
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Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Asteroseismic Signature of a Large Active Region
Axisymmetric magnetic activity on the Sun and sun-like stars increases the frequencies of the modes of acoustic oscillation. However, it is unclear how a corotating patch of activity affects the oscillations, since such a perturbation is unsteady in the ...
Emanuele Papini +2 more
doaj +1 more source
Transportation Development Division, Active Transportation Section [PDF]
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 11, 2014)Mode of ...
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Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source

