Results 81 to 90 of about 190,143 (303)

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Adding Some Smartness to Devices and Everyday Things [PDF]

open access: yes, 2000
In mobile computing, context-awareness indicates the ability of a system to obtain and use information on aspects of the system environment. To implement context-awareness, mobile system components have to be augmented with the ability to capture aspects
Schmidt, Albrecht   +2 more
core  

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth

open access: yesInternational Journal for Parasitology: Drugs and Drug Resistance, 2018
The apicomplexan parasite Sarcocystis neurona is the primary etiologic agent of equine protozoal myeloencephalitis (EPM), a serious neurologic disease of horses. Many horses in the U.S.
Gregory D. Bowden   +3 more
doaj   +1 more source

Spray-coated paper supercapacitors

open access: yesnpj Flexible Electronics, 2020
The increasing demands to further electrify and digitalize our society set demands for a green electrical energy storage technology that can be scaled between very small, and heavily distributed electrical energy sources, to very large volumes.
Mehmet Girayhan Say   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Active screen plasma surface modification of polymeric materials for biomedical application

open access: yes, 2012
Surface modification of polymers has long been known in polymer chemistry but has not yet been widely applied to biomaterials. A newly developed active screen plasma technology has a potential to treat such non-conductive materials as polymers to improve
Fu, Xin
core  

Screening active ingredients of traditional Chinese medicine by molecular docking technology and evaluating their reduce skin photoaging activities

open access: yes
Abstract ABSTRACTST Objective: Screening active ingredients of traditional Chinese medicine by molecular docking technology and evaluating their anti-skin photoaging activities. Methods: According to the verification results of molecular docking, the five active ingredients are combined in equal proportion to form a compound drug.
Shiqian Zheng   +4 more
openaire   +1 more source

Home - About - Disclaimer - Privacy