Results 131 to 140 of about 17,725,252 (297)

The Relationship between screen time and expressive language (active vocabulary and narrative production skills) in preschoolers

Психологическая наука и образование
Context and relevance. The study of the impact of electronic devices, particularly screen time (ST), on children's cognitive, emotional, and language development has become increasingly relevant in recent years, especially after the transition
E.S. Oshchepkova, A.N. Shatskaya, Y.E. Makarevskaya, A.A. Tvardovskaya   +3 more
doaj   +1 more source

Physical activity and screen time in preschool children in Croatia

Annales Kinesiologiae
This research investigates how disparities in physical activity and screen time among preschoolers can be influenced by parental education and involvement, as well as the involvement of the extended family in child-rearing. The study involved 231 parents who provided information about their children from the three (out of four) regions in Croatia.
Vesna Brumnić, Sanja Šalaj, Rado Pišot   +2 more
openaire   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

The Effects of Screen Time on Early Childhood Development: A Systematic Literature Review

Jurnal Info Kesehatan
The effects of screen time on young children warrant greater attention, particularly as screen use has increased during the COVID-19 pandemic. Excessive screen exposure in early childhood reduces opportunities for adequate stimulation and limits children’
Riama Claudia Christine Lumban Gaol, Nur Alam Fajar   +1 more
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Axial Variations and Entry Effects in a Pressure Screen [PDF]

, 2007
Pressure screens are used for contaminant removal and fibre length fractionation in the production of pulp and paper products. Axial variations and entry effects in the screen are known to occur and these variations have not been adequately quantified.
Martin John Atkins, Atkins, Martin John
core  

Screen-time exposure and modality-specific working memory capacity in adolescents

International Journal of Adolescent Medicine and Health
Electronic devices have become an integral part of adolescents’ lives, serving as a means of entertainment, education, and communication. Educational applications may enhance early reading and cognitive abilities, but excessive screen time can harm ...
Sarvajna Darshan Hosaholalu, Winston Jim Saroj, Puttanna Deepak, Odeyar Somraj, Ravindran Rasika, Sunil Kumar Krishnendu Vadakekkara, Klaykote Vettil Avani   +6 more
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source