Results 111 to 120 of about 17,725,252 (297)
Physical activity and screen-time of childhood hematopoietic stem cell transplant survivors
Aim\ud \ud Reduced bone mineral density, impaired cardiovascular fitness, and increased risk of obesity are well-known late effects of Hematopoietic Stem Cell Transplantation (HSCT) in survivors of childhood cancer.
Wakefield, Claire E. +6 more
core +1 more source
The influence of health-promoting schools on the students’ active and sedentary behaviour
Physical inactivity and levels of sedentary behaviour among students are associated with health problems, and schools are one of the institutions with the greatest potential for promoting healthy habits.
Alexandra Valencia-Peris +2 more
doaj +1 more source
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Plug flow versus mixed flow modelling of a pressure screen [PDF]
The plug flow and mixed flow methods of modelling a screen are analysed in terms of screen length, internal fibre concentration and screen separation performance. Experimental data for consistency changes in screens of narrow length are incorporated into
Walmsley, Michael R.W., Weeds, Zuben
core
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Transportation Development Division, Active Transportation Section, March 1, 2013 [PDF]
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on April 11, 2014)Mode of ...
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The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Alphaville Journal of Film and Screen Media Podcast. Episode 06, Issue 21, 'Mining Memories'
Dr. Gwenda Young, lecturer in FIlm and Screen Media at University College Cork talks with the current Irish Arts Council/UCC Film Artist in Residence Tadhg O'Sullivan about memory, collaboration and process in his film career to ...
Young, Gwenda
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