Results 11 to 20 of about 9,999,055 (259)

Differences in the localization and morphology of chromosomes in the human nucleus [PDF]

, 1999
Using fluorescence in situ hybridization we show striking differences in nuclear position, chromosome morphology, and interactions with nuclear substructure for human chromosomes 18 and 19.
Perry, P, Boyle, S, Bridger, JM, Croft, J, Bickmore, WA, Teague, P   +5 more
core   +7 more sources

Investigating the role of nuclear myosin I in the low serum induced repositioning of chromosome 10 in interphase nuclei [PDF]

, 2010
This thesis was submitted for the degree of Master of Philosophy and awarded by Brunel University.The nucleus of mammalian cells has been proven to be highly organised.
Amira, Manelle
core   +7 more sources

Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. [PDF]

PLoS ONE, 2010
The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol. Microtubule-associated protein light chain 3 (LC3) was the first protein shown to specifically label autophagosomal membranes in ...
Kimberly R Drake, Minchul Kang, Anne K Kenworthy   +2 more
doaj   +1 more source

Importin 7 mediates the nuclear import of HIV-1 integrase via a specific interacting interface. [PDF]

FEBS Open Bio
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Bana J, Yariv A, Oppenheim T, Amartely H, Reichmann D, Livnah O.   +5 more
europepmc   +2 more sources

Nuclear Export of Cyclin B Mediated by the Nup62 Complex Is Required for Meiotic Initiation in Drosophila Males

Cells, 2020
Background: The central channel of the nuclear pore complex plays an important role in the selective transport of proteins between the nucleus and cytoplasm.
Ryotaro Okazaki, Kanta Yamazoe, Yoshihiro H. Inoue   +2 more
doaj   +1 more source

Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB. [PDF]

PLoS ONE, 2013
Leishmania donovani, the causative organism for visceral leishmaniasis, contains a unique heterodimeric DNA-topoisomerase IB (LdTopIB). LdTopIB is a heterodimer made up of a large subunit and a small subunit that must interact with each other to build an
Christopher F Prada, Raquel Álvarez-Velilla, Rosario Díaz-Gozález, Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Rosa M Reguera   +5 more
doaj   +1 more source

Intracellular Localization of Blattella germanica Densovirus (BgDV1) Capsid Proteins

Viruses, 2018
Densovirus genome replication and capsid assembly take place in the nucleus of the infected cells. However, the mechanisms underlying such processes as the delivery of virus proteins to the nucleus and the export of progeny virus from the nucleus remain ...
Evgeny N. Kozlov, Elena U. Martynova, Vladimir I. Popenko, Coby Schal, Dmitry V. Mukha   +4 more
doaj   +1 more source

Mapping eGFP oligomer mobility in living cell nuclei. [PDF]

PLoS ONE, 2009
Movement of particles in cell nuclei can be affected by viscosity, directed flows, active transport, or the presence of obstacles such as the chromatin network.
Nicolas Dross, Corentin Spriet, Monika Zwerger, Gabriele Müller, Waldemar Waldeck, Jörg Langowski   +5 more
doaj   +1 more source

Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain

eLife, 2023
The development of the brain, as well as mood and cognitive functions, are affected by thyroid hormone (TH) signaling. Neurons are the critical cellular target for TH action, with T3 regulating the expression of important neuronal gene sets. However, the
Federico Salas-Lucia, Csaba Fekete, Richárd Sinkó, Péter Egri, Kristóf Rada, Yvette Ruska, Balázs Gereben, Antonio C Bianco   +7 more
doaj   +1 more source

Mouse nuclear myosin I knock-out shows interchangeability and redundancy of myosin isoforms in the cell nucleus. [PDF]

, 2013
Nuclear myosin I (NM1) is a nuclear isoform of the well-known "cytoplasmic" Myosin 1c protein (Myo1c). Located on the 11(th) chromosome in mice, NM1 results from an alternative start of transcription of the Myo1c gene adding an extra 16 amino acids at ...
Dzijak, Rastislav, Eckhard Wolf, Oliver Eickelberg, Fuchs Helmut, Alexander Bohla, Schmidt, Volker, Rülicke, T., Hrabě de Angelis, M., Rohožková, Jana, Alžběta Kalendová, Martin Hrabě de Angelis, Schmidt Volker, Dzijak, R., Kalendová, Alžběta, Rathkolb, Birgit, Hozák, Pavel, Dzijak Rastislav, Hans, Wolfgang, Ali Önder Yildirim, Rathkolb, B., Venit, Tomáš, Wolf Eckhard, Hans Wolfgang, Yildirim Ali Önder, Fuchs, H., Hozák Pavel, Bohla Alexander, Stoeger Tobias, Gailus-Durner, Valérie, Jana Rohožková, Hrabé de Angelis, Martin, Kahle-Stephan, M., Valérie Gailus-Durner, Wolf, E., Stoeger, Tobias, Thomas Rülicke, Gailus-Durner, V., Volker Schmidt, Kahle Michal, Helmut Fuchs, Kahle, Michal, Eickelberg, O., Kalendova, A., Venit Tomáš, Eickelberg Oliver, Bohla, A., Rastislav Dzijak, Michal Kahle, Rohožková Jana, Yildirim, A.Ö., Venit, T., Eickelberg, Oliver, Stöger, T., Wolfgang Hans, Rülicke Thomas, Hans, W., Rohozkova, J., Rathkolb Birgit, Bohla, Alexander, Birgit Rathkolb, Rülicke, Thomas, Tobias Stoeger, Tomáš Venit, Fuchs, Helmut, de Angelis Martin Hrabě, Schmidt, V., Yildirim, Ali Önder, Gailus-Durner Valérie, Wolf, Eckhard, Hozak, P., Kalendová Alžběta, Pavel Hozák, Venit, T. ; Dzijak, R. ; Kalendova, A. ; Kahle, M. ; Rohozkova, J. ; Schmidt, V. ; Rülicke, T. ; Rathkolb, B. ; Hans, W. ; Bohla, A. ; Eickelberg, O. ; Stöger, T. ; Wolf, E. ; Yildirim, A.Ö. ; Gailus-Durner, V. ; Fuchs, H. ; Hrabé de Angelis, M. ; Hozak, P.   +72 more
core   +2 more sources