Results 11 to 20 of about 151,960 (222)

Fragile X–Related Protein 1 Regulates Nucleoporin Localization in a Cell Cycle–Dependent Manner

Frontiers in Cell and Developmental Biology, 2021
Nuclear pore complexes (NPCs) are embedded in the nuclear envelope (NE) where they ensure the transport of macromolecules between the nucleus and the cytoplasm.
Arantxa Agote-Arán, Arantxa Agote-Arán, Arantxa Agote-Arán, Arantxa Agote-Arán, Junyan Lin, Junyan Lin, Junyan Lin, Junyan Lin, Izabela Sumara, Izabela Sumara, Izabela Sumara, Izabela Sumara   +11 more
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A Begomovirus Nuclear Shuttle Protein-Interacting Immune Hub: Hijacking Host Transport Activities and Suppressing Incompatible Functions

Frontiers in Plant Science, 2020
Begomoviruses (Geminiviridae family) represent a severe constraint to agriculture worldwide. As ssDNA viruses that replicate in the nuclei of infected cells, the nascent viral DNA has to move to the cytoplasm and then to the adjacent cell to cause ...
Laura G. C. Martins, Gabriel A. S. Raimundo, Nathalia G. A. Ribeiro, Jose Cleydson F. Silva, Nívea C. Euclydes, Virgilio A. P. Loriato, Christiane E. M. Duarte, Elizabeth P. B. Fontes   +7 more
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Nucleocytoplasmic distribution and dynamics of the autophagosome marker EGFP-LC3. [PDF]

PLoS ONE, 2010
The process of autophagy involves the formation of autophagosomes, double-membrane structures that encapsulate cytosol. Microtubule-associated protein light chain 3 (LC3) was the first protein shown to specifically label autophagosomal membranes in ...
Kimberly R Drake, Minchul Kang, Anne K Kenworthy   +2 more
doaj   +1 more source

Nuclear Export of Cyclin B Mediated by the Nup62 Complex Is Required for Meiotic Initiation in Drosophila Males

Cells, 2020
Background: The central channel of the nuclear pore complex plays an important role in the selective transport of proteins between the nucleus and cytoplasm.
Ryotaro Okazaki, Kanta Yamazoe, Yoshihiro H. Inoue   +2 more
doaj   +1 more source

Identification and characterization of the regions involved in the nuclear translocation of the heterodimeric leishmanial DNA topoisomerase IB. [PDF]

PLoS ONE, 2013
Leishmania donovani, the causative organism for visceral leishmaniasis, contains a unique heterodimeric DNA-topoisomerase IB (LdTopIB). LdTopIB is a heterodimer made up of a large subunit and a small subunit that must interact with each other to build an
Christopher F Prada, Raquel Álvarez-Velilla, Rosario Díaz-Gozález, Yolanda Pérez-Pertejo, Rafael Balaña-Fouce, Rosa M Reguera   +5 more
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Intracellular Localization of Blattella germanica Densovirus (BgDV1) Capsid Proteins

Viruses, 2018
Densovirus genome replication and capsid assembly take place in the nucleus of the infected cells. However, the mechanisms underlying such processes as the delivery of virus proteins to the nucleus and the export of progeny virus from the nucleus remain ...
Evgeny N. Kozlov, Elena U. Martynova, Vladimir I. Popenko, Coby Schal, Dmitry V. Mukha   +4 more
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Mapping eGFP oligomer mobility in living cell nuclei. [PDF]

PLoS ONE, 2009
Movement of particles in cell nuclei can be affected by viscosity, directed flows, active transport, or the presence of obstacles such as the chromatin network.
Nicolas Dross, Corentin Spriet, Monika Zwerger, Gabriele Müller, Waldemar Waldeck, Jörg Langowski   +5 more
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Axonal T3 uptake and transport can trigger thyroid hormone signaling in the brain

eLife, 2023
The development of the brain, as well as mood and cognitive functions, are affected by thyroid hormone (TH) signaling. Neurons are the critical cellular target for TH action, with T3 regulating the expression of important neuronal gene sets. However, the
Federico Salas-Lucia, Csaba Fekete, Richárd Sinkó, Péter Egri, Kristóf Rada, Yvette Ruska, Balázs Gereben, Antonio C Bianco   +7 more
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Yeast karyopherin Kap95 is required for cell cycle progression at Start

BMC Cell Biology, 2010
Background The control of the subcellular localization of cell cycle regulators has emerged as a crucial mechanism in cell division regulation. The active transport of proteins between the nucleus and the cytoplasm is mediated by the transport receptors ...
Igual Juan, Taberner Francisco
doaj   +1 more source

SARS-CoV 9b protein diffuses into nucleus, undergoes active Crm1 mediated nucleocytoplasmic export and triggers apoptosis when retained in the nucleus.

PLoS ONE, 2011
Background9b is an accessory protein of the SARS-CoV. It is a small protein of 98 amino acids and its structure has been solved recently. 9b is known to localize in the extra-nuclear region and has been postulated to possess a nuclear export signal (NES),
Kulbhushan Sharma, Sara Åkerström, Anuj Kumar Sharma, Vincent T K Chow, Shumein Teow, Bernard Abrenica, Stephanie A Booth, Timothy F Booth, Ali Mirazimi, Sunil K Lal   +9 more
doaj   +1 more source