Results 21 to 30 of about 183 (174)

A Histological and an Immunohistochemical Study on the Effects of Iron Overdose on the Basal Ganglia of the Adult Albino Rat [PDF]

open access: yesThe Egyptian Journal of Histology, 2018
Background: Iron is the most abundant element on earth and an essential metal for life. It is used extensively by proteins involved in the electron transport chain, the active centers of many enzymes and oxygen transport. It is essential for the adequate
Mohamed Saleh   +3 more
doaj   +1 more source

Dye- and fluorescence-based assay to characterize symplastic and apoplastic trafficking in soybean (Glycime max L.) endosperm

open access: yesBotanical Studies, 2019
Background Endosperm is a triploid tissue in seed resulting from a sperm nucleus fused with the binucleate central cell after double fertilization. Endosperm may be involved in metabolite production, solute transport, nutrient storage, and germination ...
Ming-Der Shih   +4 more
doaj   +1 more source

Pigment epithelium-derived factor (PEDF) interacts with transportin SR2, and active nuclear import is facilitated by a novel nuclear localization motif.

open access: yesPLoS ONE, 2011
PEDF (Pigment epithelium-derived factor) is a non-inhibitory member of the serpin gene family (serpinF1) that displays neurotrophic and anti-angiogenic properties.
Sergio Anguissola   +5 more
doaj   +1 more source

Ran GTPase: A Key Player in Tumor Progression and Metastasis

open access: yesFrontiers in Cell and Developmental Biology, 2020
Ran (Ras-related nuclear protein) GTPase is a member of the Ras superfamily. Like all the GTPases, Ran cycles between an active (GTP-bound) and inactive (GDP-bound) state.
Zied Boudhraa   +9 more
doaj   +1 more source

Defining the subcellular interface of nanoparticles by live-cell imaging. [PDF]

open access: yesPLoS ONE, 2013
Understanding of nanoparticle-bio-interactions within living cells requires knowledge about the dynamic behavior of nanomaterials during their cellular uptake, intracellular traffic and mutual reactions with cell organelles. Here, we introduce a protocol
Peter H Hemmerich, Anna H von Mikecz
doaj   +1 more source

Nucleocytoplasmic shuttling activity of ataxin-3. [PDF]

open access: yesPLoS ONE, 2009
Spinocerebellar ataxia type-3, also known as Machado-Joseph Disease (MJD), is one of many inherited neurodegenerative disorders caused by polyglutamine-encoding CAG repeat expansions in otherwise unrelated genes.
Sandra Macedo-Ribeiro   +3 more
doaj   +1 more source

Lactobacillus salivarius Promotion of Intestinal Stem Cell Activity in Hens Is Associated with Succinate-Induced Mitochondrial Energy Metabolism

open access: yesmSystems, 2022
Currently, the regulation of Lactobacillus on intestinal stem cells (ISCs) attracts broad attention, but their active ingredients and the underlying mechanism are worthy of further study.
Zhou Zhou   +10 more
doaj   +1 more source

Size-dependent steady state saturation limit in biomolecular transport through nuclear membranes.

open access: yesPLoS ONE
The nucleus preserves the genomic DNA of eukaryotic organisms and maintains the integrity of the cell by regulating the transport of molecules across the nuclear membrane.
P K Shakhi   +5 more
doaj   +1 more source

The key role of microtubules in hypoxia preconditioning-induced nuclear translocation of HIF-1α in rat cardiomyocytes [PDF]

open access: yesPeerJ, 2017
Background Hypoxia-inducible factor (HIF)-1 is involved in the regulation of hypoxic preconditioning in cardiomyocytes. Under hypoxic conditions, HIF-1α accumulates and is translocated to the nucleus, where it forms an active complex with HIF-1β and ...
Hai Guo   +5 more
doaj   +2 more sources

Protoparvovirus Knocking at the Nuclear Door

open access: yesViruses, 2017
Protoparvoviruses target the nucleus due to their dependence on the cellular reproduction machinery during the replication and expression of their single-stranded DNA genome.
Elina Mäntylä   +2 more
doaj   +1 more source

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