Results 141 to 150 of about 5,391 (252)

A Murinized Bimagrumab Analogue Increases Skeletal Muscle Mass and Improves Cardiometabolic Remodelling in Experimental Hypertrophic Cardiomyopathy

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 6, December 2026.
ABSTRACT Background Hypertrophic cardiomyopathy (HCM) involves left ventricular hypertrophy and metabolic dysfunction. Given the role of skeletal muscle in systemic metabolism, we investigated whether activin type II receptor inhibition with CDD866, a murinized bimagrumab analogue that induces skeletal muscle hypertrophy, improves physical performance ...
Tomas Baka, Sophia M. Mirrione, Fuzhong Qin, Adam C. Gower, Huamei He, Connor Haney, Kuan Ming Su, Simon T. Dillon, Towia A. Libermann, Kylie Heitman, Andrew P. Ryan, Joseph T. Brozinick, Francesca Seta, David R. Pimentel, Flora Sam, Ivan Luptak   +15 more
wiley   +1 more source

Reframing Natural Killer Cell Biology for Cancer: From Cytotoxic Potential to Context‐Matched Immune States

MedComm – Oncology, Volume 5, Issue 4, December 2026.
Natural killer (NK) cells in cancer occupy context‐dependent states shaped by exposure history, tissue adaptation, and tumor ecology. Therapeutic success requires matching NK‐cell products to dominant ecological constraints rather than relying on cytotoxicity alone.
Jinyi Dong, Yibo Zhang, Zhe Ma, Yang Liu, Yufeng Wang   +4 more
wiley   +1 more source

Benchmarking commercial large language models for gene–disease–phenotype extraction from full‐text human genetics literature

Quantitative Biology, Volume 14, Issue 4, December 2026.
Abstract Manual curation of gene–disease–phenotype relationships from the human genetics literature is a persistent bottleneck for maintaining its bioinformatics databases. Whereas large language models (LLMs) offer a promising alternative, there is currently no systematic benchmark that evaluates whether state‐of‐the‐art commercial LLMs can perform ...
Danqing Yin, Matthew Ka Siu Leung, Darren Wan Ho Pun, Fiona Haixin Chen, Julie Yujin Kwon, Xinyi Lin, Joshua W. K. Ho   +6 more
wiley   +1 more source

Associations Between Weight Loss Prior to Knee and Hip Arthroplasty and Peri‐ and Post‐Operative Outcomes: A Systematic Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 12, December 2026.
ABSTRACT Background In some of the existing literature, obesity is associated with increased complications in those who undergo lower limb arthroplasty. We conducted a systematic review and meta‐analysis to assess if pre‐arthroplasty weight loss mitigates increased post‐operative risks. Methods This systematic review and meta‐analysis was registered on
Moneet Gill, Tim Lindsay, Daniel Kevin Llanera, Tricia M.‐M. Tan, Alex Liddle, Chioma Izzi‐Engbeaya   +5 more
wiley   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, Volume 600, Issue 21, Page 3186-3200, November 2026.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Hereditary Hemorrhagic Telangiectasia of the Tongue: A Rare Case Report

Clinical Case Reports, Volume 14, Issue 11, November 2026.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT) is a rare autosomal dominant vascular disorder that may involve the oral mucosa, providing important diagnostic clues for dental practitioners. This report describes a 54‐year‐old female presenting with recurrent bleeding from multiple red‐purple telangiectatic papules on the dorsal surface of the ...
Saede Atarbashi‐Moghadam, Ali Lotfi, Fazele Atarbashi‐Moghadam, Mostafa Alam, Milad Baseri, Mohammadreza Kashefi Baher   +5 more
wiley   +1 more source

Müller Glia Subtypes Define Neuro‐Glial Associations and Spatial Morphogen Axes in the Zebrafish Retina

Glia, Volume 74, Issue 11, November 2026.
Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Samuel S. Storey, Carrie L. Hehr, Shaelene Standing, Sarah McFarlane   +3 more
wiley   +1 more source

Activin A [PDF]

Science-Business eXchange, 2010
openaire   +1 more source

AOSNP‐ADAPTR resource level‐based recommendations on practical diagnostic strategies for ependymomas

Brain Pathology, Volume 36, Issue 6, November 2026.
Adapting Diagnostic Approaches for Practical Taxonomy in Resource‐Restrained Regions (ADAPTR) recommendations for ependymomas in resource‐restrained settings (RL = resource level; created in BioRender). Abstract Ependymomas are uncommon primary tumors of the central nervous system (CNS) that affect both children and adults.
Laveniya Satgunaseelan, Michael E. Buckland, Geeta Chacko, Kenta Masui, Junji Shibahara, Vani Santosh, Maysa Al‐Hussaini, Sung‐Hye Park, Tarik Tihan, Ho‐Keung Ng, Pieter Wesseling, David N. Louis, Chitra Sarkar, Takashi Komori   +13 more
wiley   +1 more source

The crystal structure of the activin B:Fst288 complex and computational insights into the broad antagonistic activity and specificity of follistatin. [PDF]

J Biol Chem
Hok L, Walker RG, Howard JA, Gouge MM, Mast EM, Kattamuri C, Goebel EJ, Thompson TB.   +7 more
europepmc   +1 more source