Results 161 to 170 of about 4,991 (262)
Identification of novel genes regulating the development of the palate
Developmental Dynamics, Volume 255, Issue 8, Page 808-823, August 2026.Abstract Background The International Mouse Phenotyping Consortium (IMPC) has generated thousands of knockout mouse lines, many of which exhibit embryonic or perinatal lethality. Using micro‐computed tomography (micro‐CT), the IMPC has created and publicly released three‐dimensional image data sets of embryos from these lethal and subviable lines.
Ashwin Bhaskar, Sophie Astrof
wiley +1 more source
Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 4, August 2026.ABSTRACT Background A loss of muscle mass and strength is a marker of poor outcomes following surgery. Changes in muscle gene expression following surgery are likely to contribute to postsurgical muscle loss, but the mechanisms controlling these changes are not known. We have previously shown that miRNAs associate with muscle loss in disease, including
Narmin Akhundova +5 more
wiley +1 more source
CryoEM structure of ALK2:BMP6 reveals distinct mechanism that allow ALK2 to interact with both BMP and activin ligands. [PDF]
Proc Natl Acad Sci U S AGoebel EJ +6 more
europepmc +1 more source
Journal of Neuroscience Research, Volume 104, Issue 8, August 2026.Laboratory studies show KS has electroconductive properties with the ability to trap and transport protons in neurotransductive processes (Grotthuss proton shuttling). This maintains electrochemical gradients and fluxes at the neuronal cell surface in neural activation. Such processes are central to neuronal cell signaling and communication.
James Melrose
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Cell Proliferation, Volume 59, Issue 8, August 2026.The hfPSC‐LCs could be established from naïve hESCs, conventional hESCs, hiPSCs, and human blastocysts. The hfPSC‐LCs hold robust capacity for three germ layers, hPGCLCs, and hALPCs. ABSTRACT Human embryos undergo pivotal morphogenetic remodelling shortly after implantation. The understanding of this crucial stage is severely impeded by the scarcity of
Xiaoxiao Wang +11 more
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Clinical and Translational Science, Volume 19, Issue 8, August 2026.ABSTRACT Pulmonary hypertension (PH) is a complex disorder associated with significant morbidity and mortality. PH is characterized by an elevated pulmonary vascular load, leading to right ventricular dysfunction and remodeling, with right heart failure and premature death if left untreated.
Surya Ayalasomayajula +8 more
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Sotatercept: A Crosstalk Between Pathways and Activities in the Pulmonary Circulation and Blood. [PDF]
Int J Mol SciMadonna R, Ghelardoni S.
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Revisiting Pluripotency Acquisition: A Unified Framework for Reprogramming Strategies
Development, Growth &Differentiation, Volume 68, Issue 6, August 2026.ABSTRACT The traditional hierarchical view of totipotent cells generating diverse lineages of terminally differentiated cells was challenged by the discovery of induced pluripotent stem cells (iPSCs). This breakthrough demonstrated that the ectopic expression of four transcription factors, Oct4, Sox2, Klf4, and c‐Myc (OSKM), can reprogram somatic cells
Anamika Datta, Kunimasa Ohta
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Gastrointestinal pharmacology activins in liver health and disease. [PDF]
Biochem Pharmacol, 2023 Hamang M, Yaden B, Dai G.
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Journal of Cellular and Molecular Medicine, Volume 30, Issue 15, August 2026.ABSTRACT We investigated the potential of miR‐640 to downregulate CDK4/6 inhibitor resistance‐associated genes and evaluated its apoptotic, anti‐metastatic and anti‐proliferative effects, both alone and in combination with abemaciclib in breast cancer cells. miR‐640 was identified via GSE126125 dataset analysis.
Ismail Mert Alkac, Cigir Biray Avci
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