Results 91 to 100 of about 10,673,510 (116)

Sex-Specific ADNP/NAP (Davunetide) Regulation of Cocaine-Induced Plasticity. [PDF]

open access: yesJ Mol Neurosci
Toren Y   +6 more
europepmc   +1 more source

Disruption of ADNP-KDM1A-GTF2I complex drives neural differentiation imbalance in Helsmoortel-Van der Aa syndrome

open access: yes
Rizzuti L   +25 more
europepmc   +1 more source

Activity-Dependent Neuroprotective Protein (ADNP) Expression in the Amyloid Precursor Protein/Presenilin 1 Mouse Model of Alzheimer’s Disease

open access: yesJournal of Molecular Neuroscience, 2009
A major determinant in the pathogenesis of Alzheimer's disease (AD) is the deposition of beta-amyloid (Abeta) peptides in specific areas of the central nervous system. Therefore, animal models of Alzheimer amyloidosis are excellent tools to identify candidates to facilitate drug screening and to understand the molecular pathology of AD.
Fernández-Montesinos, Rafael   +6 more
openaire   +5 more sources
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Identification of the Activity‐Dependent Neuroprotective Protein (ADNP) as a Novel Effector of Gα i1

The FASEB Journal, 2022
The G i family of G protein‐coupled receptors (GPCRs) drives various cellular processes to regulate physiological functions that encompass neuronal, immune, and endocrine health. Agonist‐bound GPCRS result in the activation of the heterotrimeric G protein, leading to the dissociation of the ...
Nathalie L. Momplaisir   +3 more
openaire   +1 more source

Vasoactive Intestinal Peptide (VIP) Regulates Activity-Dependent Neuroprotective Protein (ADNP) Expression In Vivo

Journal of Molecular Neuroscience, 2007
Vasoactive intestinal peptide (VIP) is an important mediator of development during the neural tube closure period of embryogenesis and may regulate, in part, the expression of activity-dependent neuroprotective protein (ADNP), which is essential for neural tube closure and embryogenesis.
Eliezer, Giladi   +4 more
openaire   +2 more sources

Activity-dependent neuroprotective protein (ADNP) expression level is correlated with the expression of the sister protein ADNP2: Deregulation in schizophrenia

European Neuropsychopharmacology, 2011
Activity-dependent neuroprotective protein (ADNP) and the homologous protein ADNP2 provide cell protection. ADNP is essential for brain formation, proper brain development and neuronal plasticity, all reported to be impaired in the schizophrenia patient brains.
Efrat, Dresner   +2 more
openaire   +2 more sources

From Vasoactive Intestinal Peptide (VIP) Through Activity-Dependent Neuroprotective Protein (ADNP) to NAP: A View of Neuroprotection and Cell Division

Journal of Molecular Neuroscience, 2003
Accelerated neuronal death brings about cognitive as well as motor and other dysfunctions. A major neuropeptide, vasoactive intestinal peptide (VIP), has been shown to be neuroprotective. However, VIP-based drug design is hampered by the instability of the peptide and its limited bioavailability.
Illana, Gozes   +5 more
openaire   +2 more sources

Activity-dependent neuroprotective protein (ADNP)-end-binding protein (EB) interactions regulate microtubule dynamics toward protection against tauopathy

2021
The 1102-amino-acid activity-dependent neuroprotective protein (ADNP) was originally discovered by expression cloning through the immunological identification of its 8-amino-acid sequence NAPVSIPQ (NAP), constituting the smallest active neuroprotective fragment of the protein.
Yanina, Ivashko-Pachima, Illana, Gozes
openaire   +2 more sources

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