Results 101 to 110 of about 10,673,510 (116)
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The Journal of Pharmacology and Experimental Therapeutics, 2001
Brain injury induces disruption of the blood-brain barrier, edema, and release of autodestructive factors that produce delayed neuronal damage. NAPSVIPQ (NAP), a femtomolar-acting peptide, is shown to be neuroprotective in a mouse model of closed head injury.
L, Beni-Adani +8 more
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Brain injury induces disruption of the blood-brain barrier, edema, and release of autodestructive factors that produce delayed neuronal damage. NAPSVIPQ (NAP), a femtomolar-acting peptide, is shown to be neuroprotective in a mouse model of closed head injury.
L, Beni-Adani +8 more
openaire +2 more sources
Current Alzheimer Research, 2005
NAP is a short octapeptide sequence (single letter code, NAPVSIPQ) that protects neurons against a wide variety of insults. The NAP sequence was identified by peptide structure/function scanning of activity-dependent neuroprotective protein (ADNP), a gene product essential for brain formation.
Illana, Gozes +5 more
openaire +2 more sources
NAP is a short octapeptide sequence (single letter code, NAPVSIPQ) that protects neurons against a wide variety of insults. The NAP sequence was identified by peptide structure/function scanning of activity-dependent neuroprotective protein (ADNP), a gene product essential for brain formation.
Illana, Gozes +5 more
openaire +2 more sources
Localization of activity-dependent neuroprotective protein (ADNP) in neurospheres
Molecular Psychiatry, 2023Sarah A, Bennison +9 more
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Journal of Molecular Neuroscience, 2009
The dentate gyrus (DG) of the normal rat brain contains activity-dependent neuroprotective protein (ADNP) which is widely distributed in the cytoplasm of neurons and astrocytes. Treatment with nitric oxide (NO) synthase (NOS) inhibitor N(G)-nitro-L: -arginine methyl ester (L: -NAME) caused a decrease in ADNP expression in granule cells which persisted ...
Anna S, Cosgrave +4 more
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The dentate gyrus (DG) of the normal rat brain contains activity-dependent neuroprotective protein (ADNP) which is widely distributed in the cytoplasm of neurons and astrocytes. Treatment with nitric oxide (NO) synthase (NOS) inhibitor N(G)-nitro-L: -arginine methyl ester (L: -NAME) caused a decrease in ADNP expression in granule cells which persisted ...
Anna S, Cosgrave +4 more
openaire +2 more sources
Peptides, 2011
Hypobaric hypoxia is a socio-economic problem affecting cognitive, memory and behavior functions. Severe oxidative stress caused by hypobaric hypoxia adversely affects brain areas like cortex, hippocampus, basal ganglia, and cerebellum. In the present study, we have investigated the antioxidant and memory protection efficacy of the synthetic NAP ...
Narendra K, Sharma +5 more
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Hypobaric hypoxia is a socio-economic problem affecting cognitive, memory and behavior functions. Severe oxidative stress caused by hypobaric hypoxia adversely affects brain areas like cortex, hippocampus, basal ganglia, and cerebellum. In the present study, we have investigated the antioxidant and memory protection efficacy of the synthetic NAP ...
Narendra K, Sharma +5 more
openaire +2 more sources
Journal of Alzheimer's Disease, 2015
The recent finding of activity-dependent neuroprotective protein (ADNP) as a protein decreased in serum of patients with Alzheimer's disease (AD) compared to controls, alongside with the discovery of ADNP mutations in autism and coupled with the original description of cancer mutations, ignited an interest for a comparative analysis of ADNP with other ...
Illana, Gozes +2 more
openaire +2 more sources
The recent finding of activity-dependent neuroprotective protein (ADNP) as a protein decreased in serum of patients with Alzheimer's disease (AD) compared to controls, alongside with the discovery of ADNP mutations in autism and coupled with the original description of cancer mutations, ignited an interest for a comparative analysis of ADNP with other ...
Illana, Gozes +2 more
openaire +2 more sources
The Journal of Pharmacology and Experimental Therapeutics, 2023
Nathalie Momplaisir +2 more
openaire +1 more source
Nathalie Momplaisir +2 more
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A femtomolar-acting activity-dependent neuroprotective protein (ADNP)
Neuroscience Letters, 1997I. Gozes +10 more
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Activity-Dependent Neuroprotective Protein (ADNP) and Davunetide (NAP)
2013I. Gozes, P.W. Baas
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