Results 121 to 130 of about 5,846,751 (315)
The job challenges faced by healthcare unit personnel are psychological, temporal and physically demanding. Studies on psychological stress on nurses are available but unfortunately studies on physiological load or temporal anal ysis of tasks of ...
Subhashis Sahu +3 more
doaj
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Solar Power and the Electric Grid, Energy Analysis
In today’s electricity generation system, different resources make different contributions to the electricity grid. This fact sheet illustrates the roles of distributed and centralized renewable energy technologies, particularly solar power, and how they
NREL Energy Analysis
core
Background: Physical activity referral schemes (PARS) are composed of various components, such as a written prescription or a person-centered approach. The role of these components in their effectiveness is yet to be understood.
Pfeifer, Klaus +29 more
core +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
In this work we report the results of the mathematical modelling of NO◦ -release by neurons considering a series of Gaussian bursts, together with its transport in the brain by diffusion. Our analysis relies on the NO◦ -release from a&
Oleinick, A. +3 more
core +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
OBJECTIVE: To determine the effect of interventions on physical activity levels of patients awaiting abdominal resection surgery using self-reported as well as device-measured outcome measures.
Krijnen, Wim P +6 more
core
Mothers to bombers: the evolution of Indonesian women extremists
Introduction The arrest of two female would-be suicide bombers in Jakarta in December 2016 shows the desire of Indonesian women for a more active role in violent extremism. It may be a reflection of the pro-ISIS movement’s weakness that male leaders are
Institute for Policy Analysis of Conflict
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