Results 161 to 170 of about 5,846,751 (315)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Separating Overlapping Birdsongs Enhances the Reliability of Avian Vocal Activity Analysis. [PDF]

Ecol Evol
Wang J, Lai Y, Wang X, Li J, Wang Y, Shao S, Yuan M.   +6 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Biological activity, quantitative structure–activity relationship analysis, and molecular docking of xanthone derivatives as anticancer drugs

, 2018
Isnatin Miladiyah,1,2 Jumina Jumina,3 Sofia Mubarika Haryana,4 Mustofa Mustofa5 1Pharmacology Department, Faculty of Medicine, Islamic University of Indonesia, 2Doctorate Program of Medical Science and Health, Faculty of Medicine, 3Chemistry Department,
Mustofa M, Haryana SM, Miladiyah I, Jumina J   +3 more
core  

Psoriasis Triggers and Disease Activity: Analysis of Survey Data from the PSODEEP1 Study. [PDF]

Acta Derm Venereol
Duvetorp A, Reek JVD, Wikström J, Petersen MB, Zheng W, Lysell J, Skov L, Valenzuela F, Dyring-Andersen B, Eidsmo L.   +9 more
europepmc   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

REACTOR: REgulon Activity analysis and Comparison Tool for single-cell transcriptOmics Research. [PDF]

Bioinformatics
Lindén M, Zúñiga Norman SI, Välikangas T, Junttila S, Suomi T, Rytkönen KT, Elo LL.   +6 more
europepmc   +1 more source

Activation analysis with charged particles [PDF]

Acta Radiologica, 1956
openaire   +2 more sources

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Crystal Structure and Activity Analysis of <i>Chlamydophila pneumoniae</i> AP Endonuclease IV. [PDF]

Biomolecules
Jin J, Zhang Y, Guo S, Yang L, Liu H, Liu L, Gao W.   +6 more
europepmc   +1 more source