Results 171 to 180 of about 11,761,461 (345)

Correction: Auxin-mediated biosynthesis of silver nanoparticles: comprehensive characterisation and antibacterial activity analysis. [PDF]

Front Cell Infect Microbiol
Sahil, Chaudhary AA, Sorout S, Yadav K, Ali MAM, Boufahja F, Kumar V, Kothari SL, Jain D, Verma KS.   +9 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Auxin-mediated biosynthesis of silver nanoparticles: comprehensive characterisation and antibacterial activity analysis. [PDF]

Front Cell Infect Microbiol
Sahil, Chaudhary AA, Sorout S, Yadav K, Ali MAM, Boufahja F, Kumar V, Kothari SL, Jain D, Verma KS.   +9 more
europepmc   +1 more source

Tumor mutational burden as a determinant of metastatic dissemination patterns

Molecular Oncology, EarlyView.
This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal, Andrea Moreno‐Manuel, Miguel Salvadó‐Pertierra, Cristina Santos‐Vivas, Rebeca Sanz‐Pamplona   +4 more
wiley   +1 more source

Nanocarrier-Mediated Enhancement of Fusidic Acid’s Anti-Bacterial Activity: A Comparative Analysis of Its Niosomal and Liposomal Delivery Systems [PDF]

Mujeeb ur Rehman, Saima Inayat, Hafiza Arsala, Saadat Hussain, S. Noreen, Fakhar ud Din, Rukesh Maharjan   +6 more
openalex   +1 more source

A Mouse Cortex Video Segmentation Dataset for Intrinsic Optical Signal Tracking and Neural Activity Analysis. [PDF]

Sci Data
Zhang W, Zeng G, Zheng Z, Li H, Qin W, Lv J.   +5 more
europepmc   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Single-cell protein activity analysis reveals aberrant myogenesis and IGF2-PI3K pathway dependencies in <i>MYOD1</i>-mutant rhabdomyosarcoma. [PDF]

Sci Adv
Dermawan JK, Vanoli F, de Traux de Wardin H, Levi JN, Sanchez GI, Siddiquee A, Brosius S, You D, Tirode F, Sung P, Karanian M, Pissaloux D, Wexler LH, Kung A, Soragni A, Dela Cruz FS, Pavisic J, Antonescu CR.   +17 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Combining Ligand-Based Pharmacophore Modeling, Quantitative Structure−Activity Relationship Analysis and in Silico Screening for the Discovery of New Potent Hormone Sensitive Lipase Inhibitors

, 2008
Mutasem O. Taha, Lina A. Dahabiyeh, Yasser Bustanji, Hiba Zalloum, Suhair Saleh   +4 more
openalex   +1 more source