Results 171 to 180 of about 726,631 (184)

Dynamics of actomyosin filaments in the contractile ring revealed by ultrastructural analysis

Genes to Cells, 2023
AbstractCytokinesis, the final process of cell division, involves the accumulation of actin and myosin II filaments at the cell's equator, forming a contractile ring that facilitates the division into two daughter cells. While light microscopy has provided valuable insights into the molecular mechanism of this process, it has limitations in examining ...
Takeru Arima, Keisuke Okita, Shigehiko Yumura   +2 more
openaire   +2 more sources

Radial Contractility of Actomyosin Rings Facilitates Axonal Trafficking and Structural Stability

Journal of Cell Biology, 2020
Most mammalian neurons have a narrow axon, which constrains the passage of large cargoes such as autophagosomes that can be larger than the axon diameter. Radial axonal expansion must therefore occur to ensure efficient axonal trafficking. In this study, we reveal that the speed of various large cargoes undergoing axonal transport is significantly ...
Pranesh Padmanabhan, Frederic A Meunier, Rumelo Amor   +2 more
exaly   +6 more sources

Modeling Cytokinesis of Eukaryotic Cells Driven by the Actomyosin Contractile Ring

International Journal for Numerical Methods in Biomedical Engineering, 2016
SummaryA three‐dimensional (3D) hydrodynamic model for cytokinesis of eukaryotic cells is developed, in which we model dynamics of actomyosins in the cell cortex, in particular, along the cytokinetic ring formed in the cortex and in the neighborhood of the cell's division plane explicitly.
Jia Zhao, Qi Wang
exaly   +4 more sources

Regulation and Assembly of Actomyosin Contractile Rings in Cytokinesis and Cell Repair [PDF]

Anatomical Record, 2018
ABSTRACT Cytokinesis and single‐cell wound repair both involve contractile assemblies of filamentous actin (F‐actin) and myosin II organized into characteristic ring‐like arrays. The assembly of these actomyosin contractile rings (CRs) is specified spatially and temporally by small Rho GTPases, which trigger local
Craig A Mandato, Eric Boucher
exaly   +3 more sources

Cardiomyocyte Binucleation Is Associated With Aberrant Mitotic Microtubule Distribution, Mislocalization of RhoA and IQGAP3, as Well as Defective Actomyosin Ring Anchorage and Cleavage Furrow Ingression

Cardiovascular Research, 2018
AimsAfter birth mammalian cardiomyocytes initiate a last cell cycle which results in binucleation due to cytokinesis failure. Despite its importance for cardiac regenerative therapies, this process is poorly understood.
Marina Leone, Felix B. Engel
exaly   +2 more sources

Assembly of Normal Actomyosin Rings in the Absence of Mid1p and Cortical Nodes in Fission Yeast [PDF]

Journal of Cell Biology, 2008
Cytokinesis in many eukaryotes depends on the function of an actomyosin contractile ring. The mechanisms regulating assembly and positioning of this ring are not fully understood. The fission yeast Schizosaccharomyces pombe divides using an actomyosin ring and is an attractive organism for the study of cytokinesis. Recent studies in S. pombe (Wu, J.Q.,
Mohan K. Balasubramanian, Yinyi Huang
exaly   +3 more sources

Actomyosin Ring

2013
Sebastian Mana-Capelli, Dannel McCollum
openaire   +1 more source

Distinct roles of cell wall glucans and actomyosin ring in cytokinesis

2020
Peer ...
openaire   +1 more source

Grading the Severity of Damage to the Perijunctional Actomyosin Ring and Zonula Occludens-1 of the Corneal Endothelium by Ensemble Learning Methods

Journal of Ocular Pharmacology and Therapeutics, 2023
Sangly P Srinivas, Sudhir H Ranganath
exaly  

Contractile Actomyosin Ring (CAR)

2013
openaire   +1 more source