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Acute-on-chronic liver failure [PDF]
Clinical and Molecular Hepatology, 2013 Acute-on-chronic liver failure (ACLF) is an increasingly recognized distinct disease entity encompassing an acute deterioration of liver function in patients with chronic liver disease.
Tae Yeob Kim, Dong Joon Kim
doaj +5 more sources
Acute-on-Chronic Liver Failure. [PDF]
New England Journal of Medicine, 2020 Acute-on-chronic liver failure (ACLF) is a recently recognised and defined syndrome seen in patients with liver cirrhosis and carries a high short-term mortality in excess of 15% at 28 days.
V. Arroyo, R. Moreau, R. Jalan
semanticscholar +17 more sources
Acute-on-Chronic Liver Failure. [PDF]
Clinical Gastroenterology and Hepatology, 2015 Over the past 2 decades, the concept of acute-on-chronic liver failure (ACLF) has been proposed as an alternate path in the natural history of decompensated cirrhosis. ACLF thus is characterized by the presence of a precipitating event (identified or unidentified) in subjects with underlying chronic liver disease leading to rapid progression of liver ...
S. Asrani +2 more
semanticscholar +9 more sources
Acute-on chronic liver failure.
Journal of Hepatology, 2012 Acute-on-chronic liver failure (ACLF) is an increasingly recognised entity encompassing an acute deterioration of liver function in patients with cirrhosis, which is usually associated with a precipitating event and results in the failure of one or more organs and high short term mortality.
R. Jalan +7 more
semanticscholar +4 more sources
Acute-on-chronic liver failure. [PDF]
Clinics in Liver Disease, 2014 The Model for End-Stage Liver Disease (MELD) has been the single best predictor of outcome of the progression of cirrhosis. Acute-on-chronic liver failure (ACLF) has been proposed as an alternative path in the natural history of cirrhosis. ACLF occurs in patients with chronic liver disease and is characterized by a precipitating event, resulting in ...
S. Asrani, J. O’Leary
semanticscholar +4 more sources
Acute-on-Chronic Liver Failure—Current Management and Future Perspectives [PDF]
BiomedicinesAcute-on-chronic liver failure (ACLF) is a distinct clinical syndrome characterized by an acute decompensation of chronic liver disease in association with extrahepatic organ failure(s) and a high short-term mortality.
Benedict Allhoff +2 more
doaj +2 more sources
Acute-on-chronic liver failure in cirrhosis [PDF]
Nature Reviews Disease Primers, 2016 The definition of acute-on-chronic liver failure (ACLF) remains contested. In Europe and North America, the term is generally applied according to the European Association for the Study of the Liver-Chronic Liver Failure (EASL-CLIF) Consortium guidelines,
Arroyo, V +9 more
core +7 more sources
Acute-on-chronic liver failure: an update [PDF]
Gut, 2017 Acute-on-chronic liver failure (ACLF) is a syndrome characterised by acute decompensation of chronic liver disease associated with organ failures and high short-term mortality.
Ruben Hernaez +3 more
semanticscholar +4 more sources
Acute-on-Chronic Liver Failure: Steps Towards Consensus [PDF]
DiagnosticsAcute-on-chronic liver failure (ACLF) is a clinical syndrome characterized by organ failure and high short-term mortality. Since its first definition in 2013, many international organizations have defined this syndrome and, till now, there has been no ...
Loredana Gabriela Goran +2 more
doaj +2 more sources
Effect of cirrhosis on prognosis in patients with acute-on-chronic liver failure: a systematic review and meta-analysis [PDF]
PeerJBackground Acute-on-chronic liver failure (ACLF) is a prevalent complication among cirrhosis patients, whose high mortality is linked to cirrhosis combined with ACLF. Nevertheless, there is a paucity of systematic reviews.
Chunyang Dong +3 more
doaj +3 more sources