Results 21 to 30 of about 985,450 (353)
Scientific Reports, 2021 Hereditary transthyretin-mediated (hATTR) amyloidosis is an underdiagnosed, progressively debilitating disease caused by mutations in the transthyretin (TTR) gene.
Margaret M. Parker +21 more
doaj +1 more source
Acute Phase Protein Response in Goats [PDF]
Journal of Veterinary Diagnostic Investigation, 2008 Acute phase proteins (APPs) are important diagnostic indicators of inflammatory disturbances in animals. The objectives of the current study were to validate analytical methods for measuring haptoglobin (Hp), serum amyloid A (SAA), acid soluble glycoprotein (ASG), fibrinogen, and albumin concentrations in goats and to evaluate their response to an ...
Laura Soler +5 more
openaire +3 more sources
Acute-phase protein synthesis: a key feature of innate immune functions of the liver
Biological chemistry, 2021 The expression of acute-phase proteins (APP’s) maintains homeostasis and tissue repair, but also represents a central component of the organism’s defense strategy, especially in the context of innate immunity.
C. Ehlting, S. Wolf, J. Bode
semanticscholar +1 more source
C. elegans feed yolk to their young in a form of primitive lactation
Nature Communications, 2021 It is unclear why C. elegans continues to produce large quantities of yolk after reproduction. Here the authors show that post-reproductive C. elegans mothers vent yolk which supports their offspring’s growth, serving as a form of primitive lactation.
Carina C. Kern +8 more
doaj +1 more source
Acute-phase proteins during inflammatory reaction by bacterial infection: Fish-model
Scientific Reports, 2019 Acute-phase protein (APPs) serum levels have been studied in many human diseases, and their components contribute to host defense during the evolution of infectious diseases by acting as part of the innate immune system.
I. Charlie-Silva +13 more
semanticscholar +1 more source
The importance of acute-phase proteins as markers in cancers
Studia Medyczne, 2021 Acute-phase proteins (APPs) form a group of heterogeneous proteins whose synthesis takes place in the liver. This involves mediators such as cytokines and constitutes a response to acute inflammations, bacterial infections, tumours, and autoimmune ...
Paulina Zegarska +2 more
doaj +1 more source
Renal Amyloidosis Associated With 5 Novel Variants in the Fibrinogen A Alpha Chain Protein
Kidney International Reports, 2017 Fibrinogen A alpha chain amyloidosis is an autosomal dominant disease associated with mutations in the fibrinogen A alpha chain (FGA) gene, and it is the most common cause of hereditary renal amyloidosis in the UK.
Dorota Rowczenio +18 more
doaj +1 more source
Scientific Reports, 2017 Dissociation of the native transthyretin (TTR) tetramer is widely accepted as the critical step in TTR amyloid fibrillogenesis. It is modelled by exposure of the protein to non-physiological low pH in vitro and is inhibited by small molecule compounds ...
Guglielmo Verona +11 more
doaj +1 more source
Acute phase proteins in sheep and goats – function, reference ranges and assessment methods: An overview [PDF]
Bulgarian Journal of Veterinary Medicine, 2018 Acute phase response (APR) is activated by disorders in systemic homeostasis. The main purpose of APR is to prevent further tissue damage by isolation and destruction of causative agent, removing the toxic products and providing conditions for tissue ...
P. Iliev, T. Mircheva-Georgieva
doaj +1 more source
Molecular Biosystems, 2016 Acute phase proteins and a group of 77 peptides in a biomarker panel increase in milk during bovine mastitis caused by a Streptococcus uberis infection of mammary glands.
F. Thomas +8 more
semanticscholar +1 more source