Results 71 to 80 of about 6,613 (193)

What makes gouty inflammation so variable?

BMC Medicine, 2017
Acute gout arthritis flares contribute dominantly to gout-specific impaired health-related quality of life, representing a progressively increasing public health problem.
Robert Terkeltaub
doaj   +1 more source

Impact of COVID‐19 Restrictions on Estimating Causal Effects: Fluoroquinolones and Tendon Rupture

Pharmacoepidemiology and Drug Safety, Volume 35, Issue 11, November 2026.
ABSTRACT Purpose The COVID‐19 pandemic disrupted healthcare services, potentially affecting causal effect estimation using real‐world data. As a case study, we replicated a cohort study using Clinical Practice Research Datalink Aurum to evaluate whether pandemic‐related disruptions influenced the measured association between fluoroquinolone use and ...
Angel Y. S. Wong, Jeremy P. Brown, John Tazare, Marleen Bokern, Elizabeth Williamson, Jonathan Bartlett, Charlotte Warren‐Gash, Ian Douglas   +7 more
wiley   +1 more source

Inhibition of Monosodium Urate Crystal-Induced Inflammation by Withaferin A

Journal of Pharmacy & Pharmaceutical Sciences, 2009
Purpose. Gouty arthritis is a characteristically intense acute inflammatory reaction resulting from the formation of sodium urate crystals in the joint cavity.
Mahaboobkhan Rasool, Sonal Chandal, Evan Prince Sabina   +2 more
doaj   +1 more source

Indoprofen for Acute Gouty Arthritis [PDF]

Arthritis & Rheumatism, 1977
I, Caruso, M, Fumagalli, R, Marcolongo, G, Sacchetti   +3 more
openaire   +2 more sources

Continuous Intravenous Acyclovir as Outpatient Parenteral Antimicrobial Therapy for HSV and VZV Neurological Infections: A Case Series With Pharmacokinetic and Cost Evaluation, and Review of Literature

Reviews in Medical Virology, Volume 36, Issue 6, November 2026.
ABSTRACT Varicella zoster virus (VZV) and herpes simplex virus (HSV) are major causes of viral meningitis and encephalitis. Standard intermittent intravenous acyclovir requires hospitalisation, reducing patient comfort and prolonging admissions. Continuous infusion may maintain therapeutic plasma and cerebrospinal fluid (CSF) concentrations while ...
Irene G. Manders, Eline L. van Tuinen, Martijn Weisfelt, Marco Goeijenbier, Jayant S. Kalpoe, Steven F. L. van Lelyveld, Eric C. M. van Gorp, Ken Ho Hua   +7 more
wiley   +1 more source

The Lupus Damage Index Revision Program: Results From the Item Generation and Reduction Phases

Arthritis Care &Research, Volume 78, Issue 10, Page 1449-1466, October 2026.
Objective A data‐driven and expert/patient consensus‐based project to develop a revised Systemic Lupus International Collaborating Clinics (SLICC)/American College of Rheumatology (ACR) Damage Index (SDI) is under way supported by SLICC, ACR, and the Lupus Foundation of America. Our objective is to report the item generation and reduction phase results
Burak Kundakci, Megan R. W. Barber, Ann E. Clarke, Sindhu R. Johnson, Anselm Mak, Hermine I. Brunner, Murat Inanc, Rosalind Ramsey‐Goldman, Guillermo Ruiz‐Irastorza, Ellen M. Ginzler, John G. Hanly, Alexandra Legge, Cynthia Aranow, Laurent Arnaud, Nathalie Costedoat‐Chalumeau, Dafna D. Gladman, Søren Jacobsen, Michelle Petri, Clovis A. Silva, Évelyne Vinet, Alexandre E. Voskuyl, SDI Revision Literature Review Groups, SDI Revision Delphi Panel, SDI Revision Item Reduction Committee, SDI Revision Clinical Domain Groups, Ian N. Bruce   +25 more
wiley   +1 more source

N-Butyrylated hyaluronic acid ameliorates gout and hyperuricemia in animal models

Pharmaceutical Biology, 2019
Context: Hyaluronic acid (HA) plays critical roles in the structural skeleton, joint lubrication, renal function and cell signaling. We previously showed that partially N-butyrylated, low molecular weight, hyaluronic acid (BHA) exhibited an anti ...
Lanzhou Li, Di Wang, Xueju Wang, Ruifeng Bai, Chunyu Wang, Yin Gao, Tassos Anastassiades   +6 more
doaj   +1 more source

Association of Clonal Hematopoiesis With Incident, Late‐Onset, Seropositive Rheumatoid Arthritis

Arthritis &Rheumatology, Volume 78, Issue 10, Page 2063-2073, October 2026.
Objective Clonal hematopoiesis (CH), defined by acquired driver mutations in hematopoietic stem cells, is associated with many inflammatory diseases of aging. We investigated whether CH and its subtypes, CH of indeterminate potential (CHIP) and mosaic chromosomal alteration (mCA), are associated with incident rheumatoid arthritis (RA) and whether ...
Kun Zhao, Yash Pershad, J. Brett Heimlich, Michelle Ormseth, C. Michael Stein, Brian Sharber, Caitlyn Vlasschaert, Alexander G. Bick, Robert W. Corty   +8 more
wiley   +1 more source

Gout: An old disease in new perspective – A review

Journal of Advanced Research, 2017
Gout is a picturesque presentation of uric acid disturbance. It is the most well understood and described type of arthritis. Its epidemiology is studied.
Gaafar Ragab, Mohsen Elshahaly, Thomas Bardin   +2 more
doaj   +1 more source

tris‐Schiff Base Derivatives Containing Flurbiprofen as Potential Tyrosinase Inhibitors: Synthesis, In Vitro Evaluation, Molecular Docking, DFT and Dynamics Simulations

Chemistry &Biodiversity, Volume 23, Issue 10, October 2026.
New tris‐Schiff base derivatives of marketed accessible flurbiprofen were synthesised in better yields through multi‐step reactions. Structures of these compounds were deduced through 13C‐NMR and 1H‐NMR spectroscopic methods and finally screened for their in vitro tyrosinase inhibitory potential.
Aftab Alam, Muhammad Ayaz, Zainab, Majid Khan, Ahmed A. Elhenawy, Najeeb Ur Rehman, Sajjad Ur Rahman, Mumtaz Ali, Ahmed Al‐Harrasi, Manzoor Ahmad   +9 more
wiley   +1 more source