Results 151 to 160 of about 664,442 (399)

EETs Reduction Contributes to Granulosa Cell Senescence and Endometriosis‐Associated Infertility via the PI3K/AKT/mTOR Signaling Pathway

Advanced Science, EarlyView.
1) 14, 15‐EET levels were decreased in ovarian granulosa cells, follicular fluid, peritoneal fluid from endometriosis patients. 2) EETs reduction in endometriosis follicular fluid aggravated granulosa cell senescence. 3) ROS reduced 14, 15‐EET levels by upregulating EPHX2 through a mechanism involving histone methylation modification.
Xiang Lin, Weijia Gu, Xiaomei Tong, Mengru Lai, Yi Zhang, Na Liu, Xiaoying Jin, Chao Li, Dong Huang, Feng Zhou, Yongdong Dai, Songying Zhang   +11 more
wiley   +1 more source

Adjusted hypervolemic hemodilution in acute ischemic stroke. [PDF]

, 1990
M Koller, P. Haenny, Klaus Hess, Dorothea Weniger, P. Zangger   +4 more
openalex   +1 more source

Cluster-randomized, crossover trial of head positioning in acute stroke [PDF]

, 2013
The role of supine positioning after acute stroke in improving cerebral blood flow and the countervailing risk of aspiration pneumonia have led to variation in head positioning in clinical practice.
Anderson, Craig, Arima, Hisatomi, Lavados, Pablo, Billot, Laurent, Hackett, Maree, Olavarria, Veronica, Munoz-Venturelli, Paula, Brunser, Alejandro, Peng, Bin, Cui, Liying, Song, Lily, Rogers, Kerrylee, Middleton, Sandy, Lim, Joyce Y., Forshaw, Denise, Lighbody, C. Elizabeth, Woodward, Mark, Pontes-Neto, Octavio, de Silva, H. Asita, Ruey-Tay, Lin, Lee, Tay H., Pandian, Jeyaraj, Mead, Gillian, Robinson, Thompson, Watkins, Caroline Leigh   +24 more
core   +5 more sources

Human Brain Cell‐Type‐Specific Aging Clocks Based on Single‐Nuclei Transcriptomics

Advanced Science, EarlyView.
Muralidharan and colleagues develop cell‐type‐specific transcriptomic aging clocks using single‐nucleus RNA sequencing of human post mortem prefrontal cortex samples. These clocks accurately predict age and identify distinct aging trajectories in specific brain cell types.
Chandramouli Muralidharan, Enikő Zakar‐Polyák, Anita Adami, Anna A. Abbas, Yogita Sharma, Raquel Garza, Jenny G. Johansson, Diahann A. M. Atacho, Éva Renner, Miklós Palkovits, Csaba Kerepesi, Johan Jakobsson, Karolina Pircs   +12 more
wiley   +1 more source

A case of ischemic stroke in the basal ganglia presenting with fecal and urinary incontinence as initial clinical manifestations

BMC Neurology
Limb disorders and slurred speech are common clinical symptoms associated with acute ischemic stroke. Although urinary incontinence is a known symptom in many cases of acute ischemic stroke, the simultaneous impairment of both bowel and bladder function ...
Houde Li, Jiaxin Dai
doaj   +1 more source

“New Frontiers on Acute Ischemic Stroke: An Update” [PDF]

, 1991

openalex   +1 more source

Shear Stress Targeted Delivery of Nitroglycerin to Brain Collaterals Improves Ischaemic Stroke Outcome

Advanced Science, EarlyView.
Shear‐activated nanoparticles carrying nitroglycerin selectively target high‐shear stress collateral vessels during ischaemic stroke, enhancing blood flow to at‐risk brain without systemic side effects. This novel approach significantly improves outcomes in animal models, outperforming conventional nitroglycerin delivery.
Magdalena Litman, Sara Azarpeykan, Rebecca J Hood, Kristy Martin, Debbie Pepperall, Daniel Omileke, Fern Williams, Oktay Uzun, Deen Bhatta, Yuen K Yong, Alex Chan, Nicholas Hough, Sarah Johnson, Pablo Garcia Bermejo, Ferdinand Miteff, Carlos Garcia Esperon, Yvonne Couch, Alastair M Buchan, Neil J Spratt, Netanel Korin, Donald E Ingber, Daniel J Beard   +21 more
wiley   +1 more source

Ischemic stroke and inflammatory markers: a case–control study

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery
Background Ischemic stroke is a leading cause of disability and death among the elderly. The pathophysiology of stroke is complex, with oxidative stress and inflammation being key mechanisms underlying neuronal damage.
Yasmein Khaled Ahmed Mohammed, Mohamed A. Ahmed, Khaled Mohamed Hassanein, Ragaa Sedeik Rashwan   +3 more
doaj   +1 more source

Guidelines for the Early Management of Patients With Acute Ischemic Stroke: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association

Stroke, 2013
W. Powers, A. Rabinstein, Teri Ackerson, O. Adeoye, N. Bambakidis, K. Becker, J. Biller, Michael Brown, B. Demaerschalk, B. Hoh, E. Jauch, C. Kidwell, T. Leslie‐Mazwi, B. Ovbiagele, P. Scott, K. Sheth, A. Southerland, D. Summers, D. Tirschwell   +18 more
semanticscholar   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source