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Phase I and Phase II Therapies for Acute Ischemic Stroke: An Update on Currently Studied Drugs in Clinical Research. [PDF]
Acute ischemic stroke is a devastating cause of death and disability, consequences of which depend on the time from ischemia onset to treatment, the affected brain region, and its size.
Akyol, Onat+6 more
core +7 more sources
Statins for acute ischemic stroke [PDF]
Statins have been claimed to be effective in the acute phase of ischemic stroke. The potential positive actions of statins during an acute cerebrovascular ischemic event are two-fold: a neuroprotective effect, limiting damage and improving recovery; and a preventative effect on early recurrence.To quantify the potential benefits and harms of statins in
SQUIZZATO, ALESSANDRO+3 more
openaire +7 more sources
Thrombolysis for acute ischemic stroke [PDF]
Thrombolysis with intravenous alteplase is the primary therapy for acute ischemic stroke, and is approved in most countries. Early administration improves functional outcome though benefit and risk depend on the time elapsed between stroke onset and initiation of treatment. Randomized controlled trials demonstrated benefit from intravenous thrombolysis
Kennedy R. Lees+2 more
openaire +3 more sources
Review of Perfusion Imaging in Acute Ischemic Stroke: From Time to Tissue.
Perfusion imaging uses an intravascular tracer and serial imaging to quantify blood flow through the brain parenchyma. In acute ischemic stroke, perfusion imaging may increase diagnostic accuracy, aid treatment target identification, and provide ...
J. Demeestere+4 more
semanticscholar +1 more source
Acute Ischemic Stroke in Pregnancy [PDF]
Stroke is an uncommon but serious potential complication of pregnancy. The management of acute ischemic stroke in pregnant women remains a complex challenge that extends beyond the limits of clinical trial evidence. Patient 1 was a 29-year-old woman 27 weeks into her first pregnancy, without remarkable past medical history or vascular risk factors. She
Luís Fontão+4 more
openaire +4 more sources
背景和目的 本指南旨在在单个文件中为治疗急性动脉性缺血性卒中患者的临床医生提供最新的全面系列推荐意见。目标读者为院前急救人员、医生、综合医疗保健人员以及医院管理人员。本指南将取代2013年版急性缺血性卒中(acute ischemic stroke, AIS)指南,同时也是对2018年版AIS指南的更新。 方法 写作组成员由美国心脏协会(American Heart Association, AHA)卒中委员会的科学声明监督委员会任命,代表各领域的医学专家 ...
John J Warner+3 more
semanticscholar +1 more source
Treatment of Acute Ischemic Stroke due to Large Vessel Occlusion With COVID-19
Background and Purpose: Higher rates of strokes have been observed in patients with coronavirus disease 2019 (COVID-19), but data regarding the outcomes of COVID-19 patients suffering from acute ischemic stroke due to large vessel occlusion (LVO) are ...
S. Escalard+10 more
semanticscholar +1 more source
microRNA expression in peripheral blood cells following acute ischemic stroke and their predicted gene targets. [PDF]
BackgroundmicroRNA (miRNA) are important regulators of gene expression. In patients with ischemic stroke we have previously shown that differences in immune cell gene expression are present.
Ander, Bradley P+5 more
core +3 more sources
Objective To explore the expression of CD4+ effector memory T cells (CD4+ TEM) in peripheral blood of acute ischemic stroke patients with pulmonary infection, and to analyze the value of CD4+ TEM combined with interleukin⁃6 (IL⁃6) and hypersensitive C ...
HUANG Xiao⁃yu+5 more
doaj +1 more source
Background and Purpose— The purpose of these guidelines is to provide an up-to-date comprehensive set of recommendations for clinicians caring for adult patients with acute arterial ischemic stroke in a single document.
W. Powers+18 more
semanticscholar +1 more source