Results 31 to 40 of about 2,149,646 (301)

Additional outcomes and subgroup analyses of NXY-059 for acute ischemic stroke in the SAINT I trial [PDF]

, 2006
<p><b>Background and Purpose:</b> NXY-059 is a free radical-trapping neuroprotectant demonstrated to reduce disability from ischemic stroke. We conducted analyses on additional end points and sensitivity analyses to confirm our findings.
Lees, K.R., Diener, H.-C., Shuaib, A., Zivin, J.A., Davis, S.M., Wasiewski, W., Lyden, P., Emeribe, U., Ashwood, T., Hardemark, H.G., Davalos, A., Grotta, J.   +11 more
core   +1 more source

Non-coding RNAs in acute ischemic stroke: from brain to periphery

Neural Regeneration Research
Acute ischemic stroke is a clinical emergency and a condition with high morbidity, mortality, and disability. Accurate predictive, diagnostic, and prognostic biomarkers and effective therapeutic targets for acute ischemic stroke remain undetermined. With
Shuo Li, Zhaohan Xu, Shiyao Zhang, Huiling Sun, Xiaodan Qin, Lin Zhu, Teng Jiang, Junshan Zhou, Fuling Yan, Qiwen Deng   +9 more
doaj   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Lees, K.R., Hacke, W.l, Sachara, C., Rowley, H.A., Furlan, A.J., Al, R.Y., Eyding, D., Albers, G.W., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration [PDF]

, 2009
Background and Purpose—High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period.
Bath, P.M.B., M. Ali, Sare, Gillian M., Bath, Philip M.W., P. M.W. Bath, Sare, G.M., Ali, M., Shuaib, A., Ali, Myzoon, null null, Shuaib, Ashfaq, A. Shuaib, G. M. Sare   +12 more
core   +1 more source

Cerebral computed tomography perfusion pattern in Todd’s paralysis: A case series, unraveling diagnostic challenges and clinical implications

Radiology Case Reports
Acute neurological deficits following seizures can be mistaken for an acute stroke. Computed Tomography Perfusion (CTP) reveals distinct patterns in acute ischemic stroke.
Salim Al-Busaidi, MD, Tahira H Sididqui, MD, Eiman Al-Ajmi, MD, Ahmed Al-Qassabi, MD   +3 more
doaj   +1 more source

The relationship between oxidative stress and acute ischemic stroke severity and functional outcome

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020
Background Cerebral ischemia initiates an oxidative stress response in the brain which is a composite process that involves many oxidative stress biomarkers. High levels of malondialdehyde (MDA) in patients with acute ischemic stroke had been found.
Wael M. Elsayed, El-Hady A. Abdel-Gawad, Dalia I. A. Mesallam, Tamer S. El-Serafy   +3 more
doaj   +1 more source

Correlation between MMP-9 and extracellular cytokine HMGB1 in prediction of human ischemic stroke outcome [PDF]

, 2014
Ischemic stroke (IS) outcome predictors include clinical features, biochemical parameters and some risk factors. The relations between two main players in the ischemic brain, MMPs and HMGB1, were estimated in the plasma of ischemic stroke patients ...
Kalandadze, Iagor, Gugutsidze, Darejan, Shakarishvili, Roman, Sapojnikova, Nelly, Kartvelishvili, Tamar, Zinkevich, Vitaly, Tsiskaridze, Alexander, Asatiani, Nino   +7 more
core   +1 more source

Characteristic of Acute Ischemic Stroke Patients Based on TOAST Classification During COVID-19 Pandemic Era: A Single Centre Study

International Journal of General Medicine, 2023
Lisda Amalia Department of Neurology, Medical Faculty, Universitas Padjadjaran/RSUP Dr. Hasan Sadikin, Bandung, IndonesiaCorrespondence: Lisda Amalia, Jl.
Amalia L
doaj  

Associations of proinflammatory cytokines with the risk of recurrent stroke [PDF]

, 2008
<p><b>Background and Purpose:</b> There are few reports on proinflammatory cytokines and risk of primary or recurrent stroke. We studied the association of interleukin (IL)-6, IL-18, and tumor necrosis factor-α (TNF-α) with recurrent ...
Welsh, P., Chalmers, J., Lowe, G.D., Welsh, P, Woodward, M, Lowe, GD, MacMahon, SW, Neal, B.C., Campbell, DJ, Neal, BC, MacMahon, S.W., Rumley, A., Campbell, D., Chalmers, J, MacMahon, Stephen, Rumley, A, Woodward, M.   +16 more
core   +1 more source

Allopurinol use yields potentially beneficial effects on inflammatory indices in those with recent ischemic stroke: a randomized, double-blind, placebo-controlled trial [PDF]

, 2008
<p><b>Background and Purpose</b>: Elevated serum uric acid level is associated with poor outcome and increased risk of recurrent events after stroke.
Lees, K.R., Walters, M.R., Weir, C.J., Dawson, J., Muir, S.W., Sattar, N., Harrow, C.   +6 more
core   +1 more source