Results 21 to 30 of about 2,793,940 (302)

Elevated pulse pressure during the acute period of ischemic stroke is associated with poor stroke outcome [PDF]

, 2004
<p><b>Background:</b> It is controversial which component of blood pressure (BP) during acute period of stroke best predicts outcome.
Lees, K.R., Aslanyan, S., Weir, C.J., ASLANYAN S, WEIR C. J, CAROLEI, ANTONIO, LEES K. R. FOR THE GAIN INTERNATIONAL STEERING COMMITTEE AND INVESTIGATORS   +6 more
core   +1 more source

D-dimer predicts early clinical progression in ischemic stroke: confirmation using routine clinical assays [PDF]

, 2006
<p><b>Background and Purpose:</b> Plasma D-dimer levels, measured using a research laboratory assay, independently predict progressing ischemic stroke.
Lowe, G.D.O., D. J. Stott, Rumley, A., Langhorne, P., M. Barber, A. Rumley, P. Langhorne, Barber, M., Stott, D.J., G. D.O. Lowe   +9 more
core   +1 more source

The Desmoteplase In Acute Ischemic Stroke Trial (DIAS): a phase II MRI-based 9-hour window acute stroke thrombolysis trial with intravenous desmoteplase [PDF]

, 2005
<p><b>Background and Purpose:</b> Most acute ischemic stroke patients arrive after the 3-hour time window for recombinant tissue plasminogen activator (rtPA) administration.
Fischer, M., Eliasziw, M., Lees, K.R., Kaste, M., Albers, G., Al, R.Y., Hacke, W., Furlan, A., Soehngen, M., Warach, S., Warach, Steven, Lees, Kennedy R., Furlan, Anthony, Hacke, Werner, Bogousslavsky, Julien, Al-Rawi, Yasir, Albers, Greg, Fischer, Michael, Davalos, Antonio, Eliasziw, Michael, Soehngen, Mariola, Kaste, Markku   +21 more
core   +1 more source

Comparative effects of dexmedetomidine and propofol on brain and lung damage in experimental acute ischemic stroke

Scientific Reports, 2021
Acute ischemic stroke is associated with pulmonary complications, and often dexmedetomidine and propofol are used to decrease cerebral metabolic rate. However, it is unknown the immunomodulatory actions of dexmedetomidine and propofol on brain and lungs ...
Giselle C. Sousa, Marcos Vinicius Fernandes, Fernanda F. Cruz, Mariana A. Antunes, Carla M. da Silva, Christina Takyia, Denise Battaglini, Cynthia S. Samary, Chiara Robba, Paolo Pelosi, Patricia R. M. Rocco, Pedro L. Silva   +11 more
doaj   +1 more source

Thrombolysis for acute ischemic stroke [PDF]

Journal of Vascular Surgery, 2011
Thrombolysis with intravenous alteplase is the primary therapy for acute ischemic stroke, and is approved in most countries. Early administration improves functional outcome though benefit and risk depend on the time elapsed between stroke onset and initiation of treatment. Randomized controlled trials demonstrated benefit from intravenous thrombolysis
Hajjar, Karim, Kerr, Daniel M., Lees, Kennedy R.   +2 more
openaire   +2 more sources

Statistical analysis of the primary outcome in acute stroke trials [PDF]

, 2012
Common outcome scales in acute stroke trials are ordered categorical or pseudocontinuous in structure but most have been analyzed as binary measures. The use of fixed dichotomous analysis of ordered categorical outcomes after stroke (such as the modified
Lees, K.R., Saver, J.L., Howard, G., TONI, Danilo, Altman, H., Schellinger, P.D., Bland, M., Hogg, C., Bath, P.M.W., European Stroke Organisation Outcomes Working Group   +9 more
core   +1 more source

Factors associated with intracerebral hemorrhage after thrombolytic therapy for ischemic stroke pooled analysis of placebo data from the Stroke-Acute Ischemic NXY Treatment (SAINT) I and SAINT II trials [PDF]

, 2009
<p><b>Background and Purpose:</b> A number of factors have been associated with postthrombolysis intracerebral hemorrhage, but these have varied across studies.</p> <p><b>Methods:</b> We examined patients with
Demchuk, A., Lees, K.R., Kasner, S.E., Messe, S.R., Cucchiara, B., Levine, S.R., Lyden, P., Sansing, L., Tanne, D.   +8 more
core   +1 more source

Current status of stroke in hemodialysis patients on a remote island.

PLoS ONE, 2023
ObjectivesHemodialysis patients have a higher incidence of stroke than healthy individuals. Hemodialysis patients living on remote islands are subject to additional distance and transportation difficulties.
Hikaru Nakamura, Takeshi Hiu, Yasuhito Yamamoto, Shinya Oda, Tsuyoshi Izumo, Takayuki Matsuo   +5 more
doaj   +1 more source

Dose escalation of desmoteplase for acute ischemic stroke (DEDAS): evidence of safety and efficacy 3 to 9 hours after stroke onset [PDF]

, 2006
<p><b>Background and Purpose:</b> Desmoteplase is a novel plasminogen activator with favorable features in vitro compared with available agents.
Lees, K.R., Hacke, W.l, Sachara, C., Rowley, H.A., Furlan, A.J., Al, R.Y., Eyding, D., Albers, G.W., Soehngen, M., Warach, S.   +9 more
core   +1 more source

Imaging of Acute Ischemic Stroke [PDF]

European Neurology, 2014
<b><i>Background:</i></b> Over 80% of strokes result from ischemic damage to the brain due to an acute reduction in the blood supply. Around 25-35% of strokes present with large vessel occlusion, and the patients in this category often present with severe neurological deficits.
El-Koussy M, Schroth G, Brekenfeld C, Arnold M   +3 more
openaire   +3 more sources