Results 21 to 30 of about 215,645 (266)

Thrombolysis in Acute Ischemic Stroke [PDF]

The Journal of the American Board of Family Medicine, 1998
The administration of rt-PA to patients with acute ischemic stroke can result in improved functional outcomes. The safe and effective use of rt-PA in routine medical practice requires that patients seek help early, have a well-defined onset of their symptoms, be carefully examined for contraindications to rt-PA, receive a CT scan and interpretation to ...
A, Luisi, A L, Hume
openaire   +2 more sources

The relationship between oxidative stress and acute ischemic stroke severity and functional outcome

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2020
Background Cerebral ischemia initiates an oxidative stress response in the brain which is a composite process that involves many oxidative stress biomarkers. High levels of malondialdehyde (MDA) in patients with acute ischemic stroke had been found.
Wael M. Elsayed, El-Hady A. Abdel-Gawad, Dalia I. A. Mesallam, Tamer S. El-Serafy   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

The association between vitamin D and restless legs syndrome following acute ischemic stroke

Scientific Reports
Restless legs syndrome (RLS) and acute ischemic stroke are prevalent conditions in neurology. Several studies have indicated a relationship between RLS, acute ischemic stroke, and vitamin D levels.
Tianyang An, Lu Yuan, Xiuling Wu, Yiming Ma, Haiyang Sun, Baoquan Lu   +5 more
doaj   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Circulating miR-155 and JAK2/STAT3 Axis in Acute Ischemic Stroke Patients and Its Relation to Post-Ischemic Inflammation and Associated Ischemic Stroke Risk Factors

International Journal of General Medicine, 2021
Noha Adly Sadik,1 Laila Ahmed Rashed,2 Mai Ahmed Abd-El Mawla3 1Department of Internal Medicine, Faculty of Medicine, Cairo University, Cairo, Egypt; 2Department of Biochemistry and Molecular Biology, Faculty of Medicine, Cairo University, Cairo, Egypt ...
Adly Sadik N, Ahmed Rashed L, Ahmed Abd-El Mawla M   +2 more
doaj  

Validation of A2DS2 Score as Predictor of Pneumonia among Patients Hospitalized for Acute Ischemic Stroke

Jurnal Penyakit Dalam Indonesia, 2018
Introduction. Pneumonia is the leading cause of morbidity and mortality in acute ischemic stroke patients admitted to hospital. Thus required a valid scoring system which is easy to apply, to predict and stratify the risk of pneumonia in patients with ...
Toman Nababan, Ceva Wicaksono Pitoyo, Salim Harris, Cleopas Martin Rumende   +3 more
doaj   +1 more source

Overview of Acute Ischemic Stroke Evaluation and Management

Biomedicines, 2021
Stroke is a major contributor to death and disability worldwide. Prior to modern therapy, post-stroke mortality was approximately 10% in the acute period, with nearly one-half of the patients developing moderate-to-severe disability. The most fundamental
Tasneem F. Hasan, Hunaid Hasan, Roger E. Kelley   +2 more
doaj   +1 more source

Neuropsychological and neuroimaging assessments of early cognitive impairment in patients after mild ischemic stroke and transient ischemic attack [PDF]

Journal of Integrative Neuroscience, 2020
This study aimed to identify markers of early cognitive impairment after acute mild ischemic cerebrovascular disease. To further explore the relationship between neuroimaging markers of vascular and neurodegenerative injuries and post-stroke cognitive ...
Yingxia Yang, Lichao Ye, Ruoting Lin, Huasong Lin, Ting Tang, Yafang Chen, Jinying Zhang, Lingxing Wang
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source