Results 21 to 30 of about 707,511 (342)

Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury

Critical Care, 2007
IntroductionAcute kidney injury (AKI) is a complex disorder for which currently there is no accepted definition. Having a uniform standard for diagnosing and classifying AKI would enhance our ability to manage these patients.
R. Mehta, J. Kellum, Sudhir V. Shah, B. Molitoris, C. Ronco, D. Warnock, A. Levin   +6 more
semanticscholar   +1 more source

COVID-19-associated acute kidney injury: consensus report of the 25th Acute Disease Quality Initiative (ADQI) Workgroup

Nature Reviews Nephrology, 2020
Kidney involvement in patients with coronavirus disease 2019 (COVID-19) is common, and can range from the presence of proteinuria and haematuria to acute kidney injury (AKI) requiring renal replacement therapy (RRT; also known as kidney replacement ...
M. Nadim, L. Forni, R. Mehta, M. Connor, Kathleen D. Liu, M. Ostermann, T. Rimmele, A. Zarbock, S. Bell, A. Bihorac, V. Cantaluppi, E. Hoste, F. Husain‐Syed, M. Germain, S. Goldstein, Shruti Gupta, M. Joannidis, K. Kashani, J. Koyner, M. Legrand, Nuttha Lumlertgul, S. Mohan, N. Pannu, Z. Peng, X. Perez-Fernandez, P. Pickkers, J. Prowle, Thiago Reis, N. Srisawat, A. Tolwani, A. Vijayan, G. Villa, Li Yang, C. Ronco, J. Kellum   +34 more
semanticscholar   +1 more source

Protective effects of mefunidone on ischemia-reperfusion injury/Folic acid-induced acute kidney injury

Frontiers in Pharmacology, 2022
Renal ischemia-reperfusion injury (IRI) is one of the most common causes of acute kidney injury (AKI). It poses a significant threat to public health, and effective therapeutic drugs are lacking.
Jiajia Li, Jiajia Li, Jiajia Li, Yupeng Jiang, Yupeng Jiang, Yupeng Jiang, Yupeng Jiang, Qin Dai, Yue Yu, Xin Lv, Yan Zhang, Xiaohua Liao, Liyun Ao, Gaoyun Hu, Jie Meng, Jie Meng, Zhangzhe Peng, Zhangzhe Peng, Zhangzhe Peng, Lijian Tao, Lijian Tao, Lijian Tao, Yanyun Xie, Yanyun Xie, Yanyun Xie   +24 more
doaj   +1 more source

Pathophysiology of COVID-19-associated acute kidney injury

Nature Reviews Nephrology, 2021
Although respiratory failure and hypoxaemia are the main manifestations of COVID-19, kidney involvement is also common. Available evidence supports a number of potential pathophysiological pathways through which acute kidney injury (AKI) can develop in ...
M. Legrand, S. Bell, L. Forni, M. Joannidis, J. Koyner, Kathleen D. Liu, V. Cantaluppi   +6 more
semanticscholar   +1 more source

Acute kidney injury in the critically ill: an updated review on pathophysiology and management

Intensive Care Medicine, 2021
Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient’s long-term prognosis.
P. Pickkers, M. Darmon, E. Hoste, M. Joannidis, M. Legrand, M. Ostermann, J. Prowle, A. Schneider, M. Schetz   +8 more
semanticscholar   +1 more source

Acute kidney injury in critically ill patients with COVID-19

Intensive Care Medicine, 2020
Acute kidney injury (AKI) has been reported in up to 25% of critically-ill patients with SARS-CoV-2 infection, especially in those with underlying comorbidities.
P. Gabarre, G. Dumas, Thibault Dupont, M. Darmon, É. Azoulay, L. Zafrani   +5 more
semanticscholar   +1 more source

Targeting ferroptosis in acute kidney injury

Cell Death and Disease, 2022
Acute kidney injury (AKI) is a major public health problem with high incidence and mortality. As a form of programmed cell death (PCD), ferroptosis could be considered as a process of iron accumulation and enhanced lipid peroxidation.
Lihua Ni, C. Yuan, Xiaoyan Wu
semanticscholar   +1 more source

Preadmission kidney function and risk of acute kidney injury in patients hospitalized with acute pyelonephritis: A Danish population-based cohort study.

PLoS ONE, 2021
Background and objectivesOnly few smaller studies have examined if impaired kidney function increases the risk of acute kidney injury in patients with acute pyelonephritis. Therefore, we estimated 30-day risk of acute kidney injury by preadmission kidney
Henriette Vendelbo Graversen, Mette Nørgaard, Dorothea Nitsch, Christian Fynbo Christiansen   +3 more
doaj   +1 more source

Diagnosis, evaluation, and management of acute kidney injury: a KDIGO summary (Part 1)

Critical Care, 2013
Acute kidney injury (AKI) is a common and serious problem affecting millions and causing death and disability for many. In 2012, Kidney Disease: Improving Global Outcomes completed the first ever, international, multidisciplinary, clinical practice ...
J. Kellum, N. Lameire
semanticscholar   +1 more source

Mechanisms of Cisplatin-Induced Acute Kidney Injury: Pathological Mechanisms, Pharmacological Interventions, and Genetic Mitigations

Cancers, 2021
Simple Summary Nephrotoxicity is the dose-limiting factor of cisplatin treatment. Nephrotoxicity is characterized by reduced kidney function. Although an often-reversible condition, effects are notably seen years after treatment with cisplatin has ceased.
K. R. McSweeney, L. Gadanec, T. Qaradakhi, B. Ali, A. Zulli, V. Apostolopoulos   +5 more
semanticscholar   +1 more source