Results 11 to 20 of about 542,420 (309)
The role of macrophages polarization in sepsis-induced acute lung injury
Frontiers in Immunology, 2023 Sepsis presents as a severe infectious disease frequently documented in clinical settings. Characterized by its systemic inflammatory response syndrome, sepsis has the potential to trigger multi-organ dysfunction and can escalate to becoming life ...
Z. Wang, Zhong Wang
semanticscholar +1 more source
Journal of Translational Medicine, 2021 Background Acute lung injury (ALI)/acute respiratory distress syndrome (ARDS) induces uncontrolled and self-amplified pulmonary inflammation, and has high morbidity and mortality rates in critically ill patients.
Jiucui Li +9 more
semanticscholar +1 more source
American Journal of Respiratory Cell and Molecular Biology, 2022 Advancements in methods, technology, and our understanding of the pathobiology of lung injury have created the need to update the definition of experimental acute lung injury (ALI).
H. Kulkarni +49 more
semanticscholar +1 more source
Pathogenesis of pneumonia and acute lung injury.
Clinical science, 2022 Pneumonia and its sequelae, acute lung injury, present unique challenges for pulmonary and critical care healthcare professionals, and these challenges have recently garnered global attention due to the ongoing Sars-CoV-2 pandemic.
Matthew E. Long +2 more
semanticscholar +1 more source
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury [PDF]
, 2005 Acute respiratory distress syndrome (ARDS) usually requires symptomatic supportive therapy by intubation and mechanical ventilation with the supplemental use of high oxygen concentrations.
+62 more
core +8 more sources
STAT6 inhibits ferroptosis and alleviates acute lung injury via regulating P53/SLC7A11 pathway
Cell Death and Disease, 2022 Compelling evidences have revealed the emerging role of ferroptosis in the pathophysiological process of acute lung injury (ALI), but its modulation is not clear.
Youjing Yang +7 more
semanticscholar +1 more source
The role of neutrophil extracellular traps in acute lung injury
Frontiers in Immunology, 2022 Acute lung injury (ALI) is a heterogeneous inflammatory condition associated with high morbidity and mortality. Neutrophils play a key role in the development of different forms of ALI, and the release of neutrophil extracellular traps (NETs) is emerging
D. Scozzi +4 more
semanticscholar +1 more source
A Mouse-Adapted SARS-CoV-2 Induces Acute Lung Injury and Mortality in Standard Laboratory Mice
Cell, 2020 The SARS-CoV-2 pandemic has caused extreme human suffering and economic harm. We generated and characterized a new mouse-adapted SARS-CoV-2 virus that captures multiple aspects of severe COVID-19 disease in standard laboratory mice.
S. Leist +18 more
semanticscholar +1 more source
A human lung alveolus-on-a-chip model of acute radiation-induced lung injury
Nature Communications, 2023 Acute exposure to high-dose gamma radiation due to radiological disasters or cancer radiotherapy can result in radiation-induced lung injury (RILI), characterized by acute pneumonitis and subsequent lung fibrosis.
Q. Dasgupta +7 more
semanticscholar +1 more source
Guanylyl cyclase activation reverses resistive breathing–induced lung injury and inflammation [PDF]
, 2015 Inspiratory resistive breathing (RB), encountered in obstructive lung diseases, induces lung injury. The soluble guanylyl cyclase (sGC)/cyclic guanosine monophosphate (cGMP) pathway is down-regulated in chronic and acute animal models of RB, such as ...
Brouckaert, Peter +15 more
core +2 more sources