Results 41 to 50 of about 325,916 (299)

Predictive value of plasma cytokines for acute kidney injury following lung resection surgery: prospective observational study [PDF]

Revista Brasileira de Anestesiologia
Background and objectives: Patients undergoing lung resection surgery are at risk of developing postoperative acute kidney injury. Determination of cytokine levels allows the detection of an early inflammatory response.
Cristina Monteserín Matesanz, Francisco de la Gala, Lisa Rancan, Patricia Piñeiro, Carlos Simón, Alberto Tejedor, Elena Vara, Jorge L. Gonzalez-Cantero, Ignacio Garutti   +8 more
doaj   +3 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Experimental Models of Acute Lung Injury: their Advantages and Limitations

Acta Medica Martiniana, 2020
Acute damage to the lung may originate from various direct and indirect reasons. Direct lung injury may be caused by pneumonia, near-drowning, aspiration, inhalation of toxic gases etc., while indirect lung injury is secondary, following any severe extra-
Mokra D, Mikolka P, Kosutova P, Calkovska A.   +3 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source

Balanced multi-electrolyte solution versus normal saline for fluid therapy in aneurysmal subarachnoid hemorrhage: an influence on fluid and electrolytes balance and outcome

Frontiers in Medicine
IntroductionIsotonic crystalloids are commonly used for maintaining fluid balance and cerebral perfusion pressure in critical care patients with aneurysmal subarachnoid hemorrhage (aSAH).
Yu-Qing Duan, Ying Tian, Shuya Wang, Shan-Shan Xu, Ming-Yue Miao, Ran Gao, Rui Su, Mengxue Hou, Yuqing Chen, Zimeng Xu, Linlin Zhang, Jian-Xin Zhou   +11 more
doaj   +1 more source

Effect of hypertonic saline treatment on the inflammatory response after hydrochloric acid-induced lung injury in pigs

Clinics, 2015
OBJECTIVES:Hypertonic saline has been proposed to modulate the inflammatory cascade in certain experimental conditions, including pulmonary inflammation caused by inhaled gastric contents. The present study aimed to assess the potential anti-inflammatory
Carla Augusto Holms, Denise Aya Otsuki, Marcia Kahvegian, Cristina Oliveira Massoco, Denise Tabacchi Fantoni, Paulo Sampaio Gutierrez, Jose Otavio Costa Auler Junior   +6 more
doaj   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

A cluster randomized trial on inspiratory effort-targeted pressure support adjustment strategy in patients undergoing assisted mechanical ventilation: protocol for the IT-PSV study

Frontiers in Medicine
BackgroundPressure support ventilation (PSV) is one of the most frequently used ventilator modes in the intensive care unit (ICU). The successful implementation of PSV depends on matching the patient’s inspiratory effort with the ventilator support.
Wen-Yi Lu, Wen-Yi Lu, Ming-Yue Miao, Ran Gao, Yan-Lin Yang, Linlin Zhang, Li Weng, Feng-Xue Zhu, Lei Liu, Jian-Xin Zhou   +9 more
doaj   +1 more source

Tofacitinib reduces acute lung injury and improves survival in a rat model of sepsis by inhibiting the JAK-STAT/NF-κB pathway

Journal of Inflammation, 2023
Acute lung injury is a major cause of death in sepsis. Tofacitinib (TOFA), a JAK inhibitor, has anti-inflammatory activity in autoimmune diseases, but its role in acute lung injury in sepsis remains unclear.
Xinxin Zhang, Xingsheng Wang, Li Sun, Guangsheng Gao, Yun Li   +4 more
doaj   +1 more source

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source