Results 121 to 130 of about 1,516,904 (247)

Lenalidomide maintenance after initial immunochemotherapy in chronic lymphocytic leukaemia—Final analysis of the international phase III CLL6 RESIDUUM study of the ALLG and FILO groups

British Journal of Haematology, EarlyView.
Summary Most patients treated for chronic lymphocytic leukaemia (CLL) fail to achieve measurable residual disease (MRD) negativity. The role of maintenance with the immunomodulatory drug lenalidomide in these patients is unclear. A randomised multicentre phase III trial (ACTRN12610000060044) was conducted in Australia and France to assess the effect of
Thérèse Aurran‐Schleinitz, Rémi Letestu, Mary Sartor, Stephen Mulligan, Marie C. Béné, Gavin Cull, Dennis Carney, William Renwick, Andrew Grigg, Cecily Forsyth, Gregory Hapgood, Emma Verner, Rosemary Harrup, Pauline Warburton, Kylie Mason, Richard Eek, Wojciech Janowski, Jean Pierre Vilque, Maya Latimer, Laurent Voillat, Sophie De Guibert, Bernard Drenou, Robert Blum, Caroline Dartigeas, Lachlan Hayes, Nicolas Daguindau, Mourad Tiab, Véronique Leblond, Andrew Shearer, Masa Lasica, Pierre Morel, Bohrane Slama, Anne Banos, Annie Brion, Emmanuelle Ferrant, Jessica Michel, Cécile Tomowiak, Edward Morris, Hanlon Sia, Kelly Kratzing, Belinda E. Butcher, Abdelmalek Dahmani, Stephen Robert Larsen, Piers Blombery, Florence Cymbalista, David J. Gottlieb   +45 more
wiley   +1 more source

Targeting KRAS for cancer therapy

British Journal of Pharmacology, EarlyView.
In recent years, therapeutics targeted against KRAS proto‐oncogene GTPase (KRAS)‐mutant cancers have seen significant progress. Herein we outline the biology and epidemiology of KRAS alterations at the lineage and allele levels, reviewing the clinical evidence for KRASG12C inhibition from the discovery of the recessive switch pocket to sotorasib ...
Jianlong Jia, Ruonan Liu, Tonia A. Adamide, Isis E. Fernandez, Georgios T. Stathopoulos   +4 more
wiley   +1 more source

Editorial: Pediatric acute lymphoblastic leukemia: what's next?

Frontiers in Pediatrics
J. V. Gil, J. Ribera, M. Llop
doaj   +1 more source

Heart failure medication to prevent cancer therapy–related cardiac dysfunction: A narrative review

British Journal of Pharmacology, EarlyView.
Advances in oncological therapies have improved cancer survival but also have increased the clinical incidence of cancer therapy–related cardiac dysfunction (CTRCD), a spectrum of conditions ranging from subclinical biomarker or strain abnormalities to progressive heart failure and cardiogenic shock.
Fabian Voß, Paul Goerke, Malte Kelm, Amin Polzin   +3 more
wiley   +1 more source

How Hot Is Too Hot? Fever Thresholds for Initiating Antibiotics in Children With Haematological Malignancies

Acta Paediatrica, EarlyView.
C. S. V. Henriksen, U. Nygaard, G. Petersen, J. Brok, L. L. Hjalgrim, N. V. Vissing, M. B. Mønster   +6 more
wiley   +1 more source

Optimising Haematopoietic Stem Cell Transplantation: Enhancing Myeloablation Sensitivity and Alleviating Anaemia Using Roxadustat (FG‐4592)

Cell Proliferation, EarlyView.
The use of FG‐4592 in the process of myeloablation can promote haematopoietic cell apoptosis for more effective myeloablation, maintain the number of RBC and may create a pluripotent microenvironment suitable for donor cells, so as to enable more effective haematopoietic reconstruction of donor cells in vivo.
Guanheng Yang, Jiahui Wu, Xinbing Guo, Wenchen Shen, Xiao Sang, Xiuli Gong, Shu‐Zhen Huang, Jingzhi Zhang, Fanyi Zeng   +8 more
wiley   +1 more source

Primary Nodal Poroid Hidradenocarcinoma With YAP1::NUTM1 Fusion: Report of a Rare Case

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Poroid hidradenocarcinoma is a rare malignant sweat gland neoplasm. Although primary nodal hidradenoma has been reported, primary nodal poroid hidradenocarcinoma has not been described. We report a case of a 56‐year‐old man presenting with a nontender 5.5 cm mass within the axillary lymph node, and no identifiable primary cutaneous lesion on ...
Niloufar Hosseini, Omar Sbeanaty, William J. Phillips, Bryan Lo, Sandeep Sehdev, Thomas Brenn   +5 more
wiley   +1 more source

Acute Lymphoblastic Leukaemia

Apollo Medicine, 2007
Amita Mahajan
doaj   +1 more source

Venous Thromboembolism in Hematologic Malignancies: Incidence, Risk Factors, and the Role of Direct Oral Anticoagulants

European Journal of Haematology, EarlyView.
ABSTRACT Thrombotic events, particularly venous thromboembolism (VTE), are a significant source of morbidity and mortality among patients with hematologic malignancies. These patients face unique challenges due to treatment‐related complications such as thrombocytopenia, coagulopathy, and heightened bleeding risk.
Mario Biglietto, Silvia Sorella, Erminia Baldacci, Massimo Breccia, Sabina Chiaretti, Marcello Capriata, Livia Donzelli, Gianna Maria D'Elia, Salvatore Giacomo Morano, Ilaria Del Giudice, Maurizio Martelli, Cristina Santoro, Antonio Chistolini   +12 more
wiley   +1 more source

Total body irradiation is associated with increased burden of cerebral microbleeds in haematopoietic stem cell transplant recipients

British Journal of Haematology, EarlyView.
Jure Hederih, Asad Charania, Camelia Vladescu, Ira Lacej, Richard Szydlo, Jiri Pavlu, Renuka Palanicawandar, Jose Ros‐Soto, Andrew Innes, Dragana Milojkovic, Eduardo Olavarria, Jane Apperley, Adam Waldman, Nichola Cooper   +13 more
wiley   +1 more source