Cutaneous involvement by myeloid leukaemias: challenging cases with important implications
Myeloid leukaemias and precursors involving the skin are often challenging to diagnose with varied and overlapping clinical and histopathologic features. Nonetheless, they are critical for pathologists to recognize and accurately classify. This review discusses the clinical, histopathological and genetic features of myelodysplasia cutis (A) and ...
Alexandra C. Hristov
wiley +1 more source
BCL-2 and MCL1 co-inhibition enhances glucocorticoid therapy in preclinical models of infant KMT2A-rearranged acute lymphoblastic leukaemia. [PDF]
Karsa M +19 more
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ICSH Guidance on Bone Marrow Examination and Reporting
ABSTRACT Examination of the bone marrow (BM) remains fundamental to the diagnosis, classification, prognostication, and monitoring of hematolymphoid and other disorders affecting blood cell production. Since publication of the International Council for Standardization in Haematology (ICSH) guideline in 2008, advances in diagnostic technologies, disease
Wendy N. Erber +6 more
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Multiscale connectivity framework for working memory network in paediatric acute lymphoblastic leukaemia survivors. [PDF]
Raja R +6 more
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Abstract Chimeric antigen receptor (CAR) T‐cell therapies directed against cluster of differentiation 19 (CD19) are a standard of care for relapsed or refractory B‐cell lymphomas. Infection is the leading cause of non‐relapse mortality, and this risk may persist for years after CAR T‐cell receipt.
Aine Hurley +15 more
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Salivary Secretory Immunoglobulin A as a Candidate Biomarker of Oral Mucosal Vulnerability in Paediatric Acute Lymphoblastic Leukaemia: A Prospective Pilot Cohort Study. [PDF]
Serbanica IV +13 more
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ABSTRACT Aims This systematic review assesses current evidence on the management of non‐plaque (dental biofilm)‐induced gingival diseases and conditions (NPIGDs), including (i) inflammatory and immune conditions, (ii) neoplasms and (iii) gingival pigmentations.
Maria Clotilde Carra +5 more
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Chemotherapy-driven expression of WNT ligands in bone marrow stromal cells contributes to chemoresistance in acute lymphoblastic leukaemia. [PDF]
Kalampalika F +4 more
europepmc +1 more source
ABSTRACT Background Asparaginase is a critical component of modern multi‐agent chemotherapy regimens for paediatric acute lymphoblastic leukaemia and lymphoblastic lymphoma, with inadequate exposure leading to inferior patient outcomes. Objectives To develop a clinical practice guideline for the use of asparaginase products in the Australasian context.
Matthew J. O'Connor +15 more
wiley +1 more source
Prolonged molecular control during intermittent reduced-intensity blinatumomab maintenance in a transplant-ineligible patient with Philadelphia chromosome-positive acute lymphoblastic leukaemia and <i>IKZF1</i> deletion. [PDF]
Duan X, Yang J, Yang Y, Guo S, Wu Y.
europepmc +1 more source

