Results 61 to 70 of about 1,433,358 (364)
In this study, we present the structure of AcrIE8.1, a previously uncharacterized anti‐CRISPR protein that inhibits the type I‐E CRISPR‐Cas system. Through a combination of structural and biochemical analyses, we demonstrate that AcrIE8.1 directly binds to the Cas11 subunit of the Cascade complex to inhibit the CRISPR‐Cas system.
Young Woo Kang, Hyun Ho Park
wiley +1 more source
Randomized trial of polychromatic blue-enriched light for circadian phase shifting, melatonin suppression, and alerting responses. [PDF]
Wavelength comparisons have indicated that circadian phase-shifting and enhancement of subjective and EEG-correlates of alertness have a higher sensitivity to short wavelength visible light.
Ayers, M. +12 more
core +2 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Inhibition of the activity of pro-inflammatory secretory phospholipase A2 by acute phase proteins
Pro-Inflammatory non-pancreatic phospholipase A2 (sPLA2) is markedly over-expressed in acute systemic and chronic local inflammatory processes. Since in acute phase reaction sPLA2 is often over-expressed simultaneously with acute phase proteins (APP), it
W. Pruzanski, E. Stefanski, P. Vadas
doaj +1 more source
Complex training: The effect of exercise selection and training status on postactivation potentiation in rugby league players [PDF]
This study compared the postactivation potentiation (PAP) response of the hex bar deadlift (HBD) and back squat (BS) exercises. The PAP response between different levels of athletes was also compared.
Ditroilo, Massimiliano +2 more
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Hepatitis C virus core antigen assay: can we think beyond convention in resource limited settings?
Hepatitis C virus infects over 15 million patients from India and 2.86 million from Brazil. Detection of anti-hepatitis C virus antibodies has limited sensitivity during acute phase: the pre-seroconversion window period.
Anita Chakravarti +3 more
doaj +3 more sources
Effects of 48-hour feed deprivation on acute-phase response in horses
The objective of this study was to evaluate the effect of feed restriction on acute-phase response in horses. Twenty horses were deprived of food for 48 h and others 12 animals (control) had free access to water and hay.
Paula Alessandra Di Filippo +5 more
doaj
This research characterizes the acute and chronic phases of Chagas ' disease in hamster through parasitological and histopathological studies.
Luis Eduardo Ramirez +3 more
doaj +1 more source
Acute phase reaction to gadolinium-DTPA in dialysis patients [PDF]
Several late sequelae of the administration of gadolinium (Gd)-containing MRI contrast agents have been described in patients with advanced renal failure. In an observational series, we found a remarkable frequency of peracute reactions after administration of Gd-DTPA used for cardiovascular evaluation before renal transplantation.In a 26-month ...
Henning, Steen +10 more
openaire +2 more sources

