Results 61 to 70 of about 1,012,363 (342)
Identification of novel small molecule inhibitors of ETS transcription factors
FEBS Letters, EarlyView.ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla +9 more
wiley +1 more source
Inhibition of the activity of pro-inflammatory secretory phospholipase A2 by acute phase proteins
Mediators of Inflammation, 1996 Pro-Inflammatory non-pancreatic phospholipase A2 (sPLA2) is markedly over-expressed in acute systemic and chronic local inflammatory processes. Since in acute phase reaction sPLA2 is often over-expressed simultaneously with acute phase proteins (APP), it
W. Pruzanski, E. Stefanski, P. Vadas
doaj +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
Effects of 48-hour feed deprivation on acute-phase response in horses
Ciência Animal Brasileira, 2022 The objective of this study was to evaluate the effect of feed restriction on acute-phase response in horses. Twenty horses were deprived of food for 48 h and others 12 animals (control) had free access to water and hay.
Paula Alessandra Di Filippo +5 more
doaj
Revista da Sociedade Brasileira de Medicina Tropical, 1994 This research characterizes the acute and chronic phases of Chagas ' disease in hamster through parasitological and histopathological studies.
Luis Eduardo Ramirez +3 more
doaj +1 more source
Data-driven dynamic treatment planning for chronic diseases [PDF]
arXiv, 2022 In order to deliver effective care, health management must consider the distinctive trajectories of chronic diseases. These diseases recurrently undergo acute, unstable, and stable phases, each of which requires a different treatment regimen. However, the correct identification of trajectory phases, and thus treatment regimens, is challenging.
arxiv
Evolution of replication efficiency following infection with a molecularly cloned feline immunodeficiency virus of low virulence [PDF]
, 2002 The development of an effective vaccine against human immunodeficiency virus is considered to be the most practicable means of controlling the advancing global AIDS epidemic.
Cannon, C. +7 more
core +2 more sources
Social context prevents heat hormetic effects against mutagens during fish development
FEBS Letters, EarlyView.This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere +5 more
wiley +1 more source
ACUTE-PHASE REACTIONS, INCLUDING CYTOKINES, IN PATIENTS BITTEN BY BOTHROPS AND CROTALUS SNAKES IN BRAZIL [PDF]
, 1995 Benedito Barraviera +4 more
+4 more sources
miRNA‐29 regulates epidermal and mesenchymal functions in skin repair
FEBS Letters, EarlyView.miRNA‐29 inhibits cell‐to‐cell and cell‐to‐matrix adhesion by silencing mRNA targets. Adhesion is controlled by complex interactions between many types of molecules coded by mRNAs. This is crucial for keeping together the layers of the skin and for regenerating the skin after wounding.
Lalitha Thiagarajan +10 more
wiley +1 more source