Results 91 to 100 of about 507,051 (317)

Using historical lesion volume data in the design of a new phase II clinical trial in acute stroke [PDF]

, 2009
<p><b>Background and Purpose:</b> Clinical research into the treatment of acute stroke is complicated, is costly, and has often been unsuccessful.
Bolland, Kim, Lees, Kennedy J., Lihic, A., Bolland, K., Lihic, A., Lees, Kennedy, Ali, M., Lihic, Anela, Lees, K.R., Valdes-Marquez, E., Bolland, K., Whitehead, J., Ali, Myzoon, Valdes-Marquez, E., Whitehead, J., Ali, M., Whitehead, John, Lees, K., Valdés-Márquez, Elsa   +18 more
core   +1 more source

Reperfusion‐Dependent Outcomes After Endovascular Thrombectomy Stratified by NIHSS‐ASPECTS Clinical‐Core Mismatch

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective This analysis evaluates the effect of successful reperfusion on functional outcomes after MT, stratified by admission National Institutes of Health Stroke Scale (NIHSS) and Alberta Stroke Program Early CT Score (ASPECTS) as surrogates for clinical‐core mismatch, using multicenter registry data.
Felix Schlicht, Lukas Meyer, Gabriel Broocks, Matthias Bechstein, Christian Thaler, Christian Heitkamp, Laurens Winkelmeier, Vincent Geest, Alexander Heitkamp, Maximilian Jungnitz, Gregor Peter, Luca Meucci, Tobias Faizy, Jawed Nawabi, Caspar Brekenfeld, Fabian Flottmann, Maximilian Schell, Alexandros Hadjilaou, Uta Hanning, Götz Thomalla, Jens Fiehler, Susanne Gellißen, Helge C. Kniep, for the German Stroke Registry Endovascular Treatment, (GSR‐ET) Alexander Nave, Anna Alegiani, Annerose Mengel, Arno Reich, Bernd Eckert, Charlotte Pietrock, Christian Nolte, Eberhard Siebert, Fabian Flottmann, Fee Keil, Franziska Dorn, Gabor Petzold, Götz Thomalla, Hanna Zimmermann, Jan Borggrefe, Jan Hendrik Schäfer, Jens Fiehler, Joachim Röther, Klaus Gröschel, Lars Kellert, Mario Abruscato, Maximilian Schell, Omid Nikoubashman, Peter Schellinger, Silke Wunderlich, Steffen Tiedt, Sven Thonke, Timo Uphaus, Tobias Boeckh‐Behrens, Ulrike Ernemann   +53 more
wiley   +1 more source

Relationship between hyperacute blood pressure and outcome after ischemic stroke: data from the VISTA Collaboration [PDF]

, 2009
Background and Purpose—High blood pressure (BP) is associated independently with poor outcome after acute ischemic stroke, although in most analyses “baseline” BP was measured 24 hours or more postictus, and not during the hyperacute period.
Bath, P.M.B., M. Ali, Sare, Gillian M., Bath, Philip M.W., P. M.W. Bath, Sare, G.M., Ali, M., Shuaib, A., Ali, Myzoon, null null, Shuaib, Ashfaq, A. Shuaib, G. M. Sare   +12 more
core   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

Effects of music-based group exercise in patients with acquired brain injury—a randomized controlled trial

Frontiers in Psychology
BackgroundCognitive impairment following acquired brain injury (ABI) is common. In this study, we investigated whether music-based group exercise (MBGE) is superior to standard therapy (ST) in improving cognitive deficits.
Mareike Schrader, Mareike Schrader, Tobias Strank, Annette Sterr, Stephan Bamborschke, Stephan Bamborschke, Christian Dohle, Christian Dohle, Christian Dohle   +8 more
doaj   +1 more source

Impact on Clinical and Cost Outcomes of a Centralized Approach to Acute Stroke Care in London: A Comparative Effectiveness Before and After Model

, 2013
Background In July 2010 a new multiple hub-and-spoke model for acute stroke care was implemented across the whole of London, UK, with continuous specialist care during the first 72 hours provided at 8 hyper-acute stroke units (HASUs) compared to the ...
Rachael Maree Hunter (393680), Mountford, James, Davie, C, Stephen Morris (324510), Stephen Morris, Thompson, A, Hilary Walker, Quoraishi, S, Bikash Dewan (440513), Thompson, Alan, Sadik Quoraishi, Mountford, J, Charles Davie (440505), John Deanfield (256140), Deanfield, John, Lee Schwamm, Minesh Mistry (440514), Kerry Thompson (440512), Anthony Rudd (440506), Morris, Stephen, Dewan, Bikash, Neil Thomson, Walker, H, Walker, Hilary, John Deanfield, James Mountford (440510), James Mountford, Schwamm, L, Neil Thomson (440509), Lee Schwamm (440511), Hunter, Rachael Maree, Schwamm, Lee, Minesh Mistry, Davie, Charles, Quoraishi, Sadik, Rudd, A, Charles Davie, Anthony Rudd, Thomson, N, Bikash Dewan, Mistry, Minesh, Rachael Maree Hunter, Thomson, Neil, Hilary Walker (440508), Deanfield, J, Morris, S, Thompson, K, Hunter, Rachael M., Dewan, B, Thompson, Kerry, Sadik Quoraishi (440515), Rudd, Anthony, Hunter, RM, Mistry, M, Alan Thompson, Kerry Thompson, Alan Thompson (440507)   +56 more
core   +1 more source

IV Thrombolysis Facilitates Interventional Reperfusion in Non‐Cardioembolic but Not Cardioembolic Stroke

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intravenous thrombolysis (IVT) before thrombectomy for ischemic stroke may alter clot structure and procedural performance. We investigated how IVT relates to thrombectomy metrics across stroke etiologies. Methods We performed a time‐to‐event analysis of consecutive patients with anterior circulation large vessel occlusion (acLVO ...
Annahita Sedghi, Daniel P. O. Kaiser, Martin Arndt, Norma J. Diel, Erik Simon, Witold H. Polanski, Volker Puetz, Hagen B. Huttner, Timo Siepmann   +8 more
wiley   +1 more source

NXY-059 for the treatment of acute stroke: pooled analysis of the SAINT I and II trials [PDF]

, 2008
<p><b>Background and Purpose:</b> In animal models of acute ischemic stroke (AIS), the free radical-trapping agent NXY-059 showed promise as a neuroprotectant.
Lees, K.R., Shuaib, A., Diener, H.C., Alderfer, V., Davis, S.M., Wasiewski, W., Lyden, P., Rodichok, L., Ashwood, T., Hardemark, H.G., Davalos, A., Grotta, J.   +11 more
core   +1 more source

Effectiveness of rTMS on Working Memory and Inhibitory Impairments in Patients With Post‐Stroke Executive Deficits

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Considerable efforts have been dedicated to developing effective treatments for post‐stroke executive impairment (PSEI), among which repetitive transcranial magnetic stimulation (rTMS) has shown great potential. This study aimed to investigate the therapeutic effects of high‐frequency rTMS on working memory (WM) and response ...
Mengting Lao, Rongwei Du, Zhujun Wang, Yang Gao, Meiling Cheng, Xianglong Wang, Wen Wu   +6 more
wiley   +1 more source

Penetrating neck trauma: a comprehensive review

Trauma Surgery & Acute Care Open
Although the overall incidence is low, penetrating neck trauma can result in devastating injuries. The traditional zonal approach is being increasingly abandoned in favor of selective approaches, especially as mandatory exploration can result in non ...
Kenji Inaba, Martin Schreiber, Kazuhide Matsushima, Christopher Barrett, ANNA WHITE, Reynold Henry, Daniel Lammers, Lindsey Loss   +7 more
doaj   +1 more source