Results 81 to 90 of about 507,051 (317)

Hyperglycemia in Acute Stroke [PDF]

Stroke, 2004
Elevated blood glucose is common in the early phase of stroke. The prevalence of hyperglycemia, defined as blood glucose level >6.0 mmol/L (108 mg/dL), has been observed in two thirds of all ischemic stroke subtypes on admission and in at least 50% in each subtype including lacunar strokes.1 Extensive experimental evidence in stroke models supports ...
Perttu J, Lindsberg, Risto O, Roine
openaire   +2 more sources

Assessment of additional endpoints for trials in acute stroke - what, when, where, in who?

, 2012
Functional outcome in acute stroke trials among others is usually measured on the modified Rankin Scale. However, new onset of depression, cognitive decline, and communication deficits alone or in combination affect more than 25% of patients. This report
TONI, Danilo, European Stroke Organisation Outcomes Working Group   +1 more
core   +1 more source

Comparison of the National Institutes of Health Stroke Scale with disability outcome measures in acute stroke trials [PDF]

, 2005
<p><b>Background and Purpose:</b> Acute stroke trials typically use disability scales as their primary end point. Neurologic impairment scales such as the National Institutes of Health Stroke Scale (NIHSS) are possibly more sensitive to
Lees, K.R., Weir, C.J., Young, F.B.
core   +1 more source

Paramagnetic Rim Lesions Are Associated With Trans‐Synaptic Degeneration of the Visual Pathway in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Retrograde trans‐synaptic degeneration (rTSD) from posterior visual pathway lesions in multiple sclerosis (MS) is characterized by hemi‐macular ganglion cell‐inner plexiform layer (GCIPL) thinning and contralateral visual field loss.
Abdul Jaber Tayem, Angel Liu, Sargis Manukyan, Mustafa Subhi, Elaina Luskin, Bryan Quah, Sreekanth Madhusoodhanan Nair, Arzu C. Has Silemek, Gabriela Zabala, Yujie Cui, Laura Locke, Paula Barreras, Marwa Kaisey, Vinicius Calsavara, Daniel S. Reich, Nancy L. Sicotte, Pascal Sati, Omar Al‐Louzi   +17 more
wiley   +1 more source

The FHJ debate: There is no evidence for the drive towards virtual wards

Future Healthcare Journal
Virtual wards and hospital at home are rapidly growing models of care globally and in the UK. Evidence is growing around positive impact of specialist-led hospital at home care for frail, multimorbid patients in comparison to traditional hospital ...
Tim Cooksley, Kyaw Myat Thu
doaj   +1 more source

Normal‐Appearing White Matter Injury Mediates Chronic Deep Venous Hypoxia and Disease Progression in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To explore how cerebral hypoxia and Normal‐Appearing White Matter (NAWM) integrity affect MS lesion burden and clinical course. Methods Seventy‐nine MS patients, including 13 clinically isolated syndrome (CIS) patients and 66 relapsing–remitting multiple sclerosis (RRMS) patients, and 44 healthy controls (HCs) were recruited from ...
Xinli Wang, Huiying Wang, Zhizheng Zhuo, Ai Guo, Ke Lv, Decai Tian, Chao Chai, Yunyun Duan, Shuang Xia   +8 more
wiley   +1 more source

Navigating recovery: A qualitative interview study of patients’ experiences of a structured group-based educational programme after transient ischemic attack or minor stroke

Nordic Journal of Nursing Research
Patients with transient ischemic attack (TIA) and minor stroke often struggle with long-term cognitive and psychological difficulties that impact their reintegration into work and leisure activities.
Amanda Agnes Østervig Buus, Lene Kjærhauge Christiansen, Karin Bundgaard   +2 more
doaj   +1 more source

Demographic, clinical and radiological characteristics of patients with acute ischemic stroke and acute symptomatic seizures [PDF]

Medicinski Podmladak
Introduction: A growing number of stroke survivors face various stroke complications, including acute symptomatic seizures. Symptomatic seizures are associated with longer hospitalizations, negative functional outcomes, and lower quality of life for ...
Baljak Anja, Kovačević Maša
doaj   +1 more source

Sex Representation in US Stroke Clinical Trials: A Decade of Trends and Challenges

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Stroke remains a major cause of disability and mortality in the US, with significant sex‐based disparities, and females remain underrepresented in stroke clinical trials. We aimed to examine sex representation in US‐based stroke clinical trials, identify trial characteristics associated with higher female enrollment (≥ 50%), and ...
Chaitali Dagli, Mudasir Andrabi, Tova Cohen, Pranali G. Patel, Tapasya Katta, Chen Lin   +5 more
wiley   +1 more source

Extending mechanical thrombectomy service provision to 24/7: a break-even analysis

BMC Health Services Research
Background Comprehensive stroke centres across England have developed investment proposals, showing the estimated increases in mechanical thrombectomy (MT) treatment volume that would justify extending the standard hours to a 24/7 service provision ...
Joyce S. Balami, Gary A. Ford, Alastair M. Buchan, Alastair Gray, Andrea Francesconi, Paolo Collini, Paolo Candio   +6 more
doaj   +1 more source