Results 81 to 90 of about 4,781,689 (344)

Biomarkers of leukemia risk: benzene as a model. [PDF]

, 1998
Although relatively rare, leukemias place a considerable financial burden on society and cause psychologic trauma to many families. Leukemia is the most common cancer in children.
Smith, MT, Zhang, L
core   +3 more sources

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Phytochemistry and toxicological assessment of Bryonia dioica roots used in north-African alternative medicine

Open Chemistry, 2019
To investigate the phytochemical composition, acute and sub-acute toxicity of the aqueous extract of B. dioica roots. The phytochemical analysis was performed using gas chromatography-mass spectrometry (GC-MS).
Bourhia Mohammed, Bari Ahmed, Ali Syed Saeed, Benbacer Laila, khlil Naima   +4 more
doaj   +1 more source

Evaluation of the acute and sub-acute toxicity of the black caraway seed essential oil in Wistar rats

Toxicology Reports, 2019
The aim of the present study was to evaluate the acute toxicity as lethal dose 50% (LD50) and sub-acute toxicity of the black caraway Bunium persicum (Bioss) seed essential oil in male Wistar rats. The compounds of B.
Hadi Tabarraei, Jalal Hassan, Mohammad Reza Parvizi, Hannaneh Golshahi, Hossain keshavarz-Tarikhi   +4 more
doaj   +1 more source

Experimental evolution reveals high insecticide tolerance in Daphnia inhabiting farmland ponds [PDF]

, 2015
Exposure of nontarget populations to agricultural chemicals is an important aspect of global change. We quantified the capacity of natural Daphnia magna populations to locally adapt to insecticide exposure through a selection experiment involving ...
Agra, Agra, Angel, Barata, Carriere, Cerbin, Colbourne, Coors, Crawley, De Meester, Decaestecker, Declerck, Goussen, Hebert, Hoffman, Jansen, Kerr, Klüttgen, Lampert, Levinton, McCullagh, Medina, Messiaen, Miner, Muyssen, Naddy, Parker, Raymond, Saro, Sibly, Tanaka, Van Doorslaer, Van Doorslaer, Van Straalen, Walker, Waterfield, Wheeler   +36 more
core   +2 more sources

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Periodical assessment of genitourinary and gastrointestinal toxicity in patients who underwent prostate low-dose-rate brachytherapy

Radiation Oncology, 2013
Background To compare the periodical incidence rates of genitourinary (GU) and gastrointestinal (GI) toxicity in patients who underwent prostate low-dose-rate brachytherapy between the monotherapy group (seed implantation alone) and the boost group (in ...
Tanaka Nobumichi, Asakawa Isao, Anai Satoshi, Hirayama Akihide, Hasegawa Masatoshi, Konishi Noboru, Fujimoto Kiyohide   +6 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Acute and subchronic oral toxicity assessments of Combretum micranthum (Combretaceae) in Wistar rats

Toxicology Reports, 2020
Background: Combretum micranthum (CM) (Combretaceae) is widely used in traditional medicine throughout West Africa for the treatment of diabetes, hypertension, inflammation, malaria and liver ailments.
Mabozou Kpemissi, Kossi Metowogo, Mamatchi Melila, Veeresh P. Veerapur, Mihai Negru, Marian Taulescu, Adrian-Valentin Potârniche, Doddamavattur Shivalingaiah Suhas, Tumbadi Adinarayanashetty Puneeth, Sachidananda Vijayakumar, Kwashie Eklu-Gadegbeku, Kodjo Aklikokou   +11 more
doaj   +1 more source

Acute toxicity of Gammalin 20 to Chrysichthys nigrodigitatus (Lacepede) [PDF]

, 2003
The impact of acute exposure of Gammalin 20 (an organochlorine pesticide) was investigated in a static bioassay test over a 96-(4-day) period on the fingerlings of Chrysichthys nigrodigitatus (lacepede).
Oti, E.E.
core