Results 161 to 170 of about 7,648 (236)

Theoretical-Experimental Analysis to Elucidate the Mechanism of Action of Novel Anabolic Agents. [PDF]

Molecules
Quiroga I, Cardenas-Garcia M, Hernández-Linares MG, Guerrero-Luna G, Flores-Manuel F.   +4 more
europepmc   +1 more source

HG-67PRECLINICAL EFFICACY OF ALK2 INHIBITORS IN ACVR1 MUTANT DIPG [PDF]

Neuro-Oncology, 2016
Diana Carvalho, Kathryn Taylor, Nagore G. Olaciregui, Melanie Valenti, Ruth Ruddle, Alan Henley, Angela Hayes, Alexis De Haven Brandon, Albert Hallsworth, Alan Mackay, Valeria Molinari, Maria Vinci, Sergey Popov, Aicha Boudhar, Paul Brennan, Andrew Moore, Liam Hudson, Swen Hoelder, Alex Bullock, Florence Raynaud, Sue Eccles, Angel M. Carcaboso, Chris Jones   +22 more
openaire   +1 more source

A new BMP type 1 receptor kinase inhibitor for safe and efficient oral treatment to prevent genetically induced heterotopic ossification in mice. [PDF]

Bone
Yang J, Pan H, Sekimata K, Hwang C, Kulkarni A, Thomas H, Lindenau J, Duford T, Ueharu H, Tanaka A, Sakai N, Shirouzu M, Hashizume Y, Levi B, Koyama H, Mishina Y.   +15 more
europepmc   +1 more source

Inhibition of astrocyte BMP signaling alleviates neuroinflammation in experimental models of Parkinson's disease. [PDF]

Cell Death Discov
Li Y, Li Y, Hao J, Wang W, Su Z, Tian X, Wang H, Liu Q, Gao J, Geng D, Wang L.   +10 more
europepmc   +1 more source

An inducible knock-in mouse model of fibrodysplasia ossificans progressiva shows spontaneous formation of heterotopic ossification. [PDF]

JBMR Plus
Chakkalakal SA, Großmann NZ, Mejías Rivera L, Roberts DW, Pacifici M, Mourkioti F, Shore EM.   +6 more
europepmc   +1 more source

GNAS/PKA signaling promotes aberrant osteochondral differentiation of Gli1⁺ tendon sheath progenitors. [PDF]

EMBO J
Chen L, Peng C, Chai L, Zhang R, Zhu C, Wang H, Cheng Q, Yan Y, Shen C, Zheng H, Yang J, Fan H, Kan C.   +12 more
europepmc   +1 more source

PDTB-20. PRECLINICAL EFFICACY OF ALK2 INHIBITORS IN ACVR1 MUTANT DIPG [PDF]

Neuro-Oncology, 2016
Diana Carvalho, Kathryn Taylor, Nagore Gene Olaciregui, Melanie Valenti, Ruth Ruddle, Alan Henley, Angela Hayes, Alexis De Haven Brandon, Alan MacKay, Valeria Molinari, Maria Vinci, Sergey Popov, Paul Brennan, Andrew Moore, Liam Hudson, Swen Hoelder, Alex Bullock, Florence Raynaud, Sue Eccles, Angela Montero Carcaboso, Chris Jones   +20 more
openaire   +1 more source

Advancements in mechanisms and drug treatments for fibrodysplasia ossificans progressiva. [PDF]

J Zhejiang Univ Sci B
Zhou Y, Shi C, Sun H.
europepmc   +1 more source

PI3Kα inhibition blocks osteochondroprogenitor specification and the hyper-inflammatory response to prevent heterotopic ossification. [PDF]

Elife
Valer JA, Deber A, Wits M, Pimenta-Lope C, Goumans MJ, Rosa JL, Sánchez-Duffhues G, Ventura F.   +7 more
europepmc   +1 more source

ACVR1 mutations—a key piece in paediatric diffuse glioma [PDF]

Nature Reviews Clinical Oncology, 2014
openaire   +1 more source