Results 171 to 180 of about 5,020 (198)

ACVR1, A Therapeutic Target of Fibrodysplasia Ossificans Progressiva, Is Negatively Regulated by miR-148a

International Journal of Molecular Sciences, 2012
Fibrodysplasia ossificans progressiva (FOP) is a rare congenital disorder of skeletal malformations and progressive extraskeletal ossification. There is still no effective treatment for FOP.
Hao Song, De-Li Zhang, Xuesong Gao
exaly   +2 more sources

Some of the next articles are maybe not open access.

Related searches:

ACVR1 Is Essential for Periodontium Development and Promotes Alveolar Bone Formation

Archives of Oral Biology, 2018
To explore the role of a BMP type I receptor (ACVR1) in regulating periodontium development, Acvr1 was conditionally disrupted in Osterix-expressing cells.Mandibles from both control (Acvr1 fx/+; Osterix-Cre (+)/(-)) and cKO (Acvr1 fx/-; Osterix-Cre (+)/(-)) mice at postnatal day 21 (PN21) were scanned by micro-CT, followed by decalcification and ...
Yue Hu, Hongchen Sun, Guangxing Yan
exaly   +3 more sources

Functional Modeling of the ACVR1 (R206H) Mutation in FOP

Clinical Orthopaedics & Related Research, 2007
Individuals with fibrodysplasia ossificans progressiva are born with malformations of the great toes and develop a heterotopic skeleton during childhood because of an identical heterozygous mutation in the glycine-serine activation domain of ACVR1, a bone morphogenetic protein type I receptor.
Jay C, Groppe, Eileen M, Shore, Frederick S, Kaplan   +2 more
openaire   +2 more sources

ACVR1 Mutations—A Key Piece in Paediatric Diffuse Glioma [PDF]

Nature Reviews Clinical Oncology, 2014
M Teresa Villanueva
exaly   +2 more sources

ACVR1 mutations and the genomic landscape of pediatric diffuse glioma

Nature Genetics, 2014
Pediatric diffuse gliomas are rare but aggressive brain tumors for which effective therapies are unavailable. New studies identify recurrent mutations of the ACVR1 gene in these tumors, identify molecular subtypes and highlight differences between gliomas affecting children and adults.
Gelareh Zadeh, Kenneth Aldape
openaire   +1 more source

Monoallelic variants in ACVR1 in a cohort of Egyptian individuals with fibrodysplasia ossificans progressiva

Clinical Dysmorphology
Objectives Fibrodysplasia ossificans progressiva (FOP) is a rare ectopic ossification disorder of connective tissue deposited in the muscles, fascia, tendons, and ligaments. The disease is an autosomal dominant pattern caused by pathogenic variants of ACVR1.
Rasha M, Elhossini, Hala T, El-Bassyouni, Engy A, Ashaat, Adel M, Ashour, Khaled, Hamed, Doaa R, Soliman, Ibrahim, Hegazy, Sawsan, Abdel-Hadi, Hasnaa M, Elbendary, Mennat, Mehrez, Nehal F, Hassib, Mohamed A, Al Kersh, Amal I, Othman, Ghada M H, Abdel-Salam, Mohamed S, Abdel-Hamid, Mona S, Aglan   +15 more
openaire   +2 more sources

ACVR1 Gene

2020
openaire   +1 more source

ANTI-ACVR1 ANTIBODIES AND USES THEREOF

2021
IDONE VINCENT J, HATSELL SARAH J, ECONOMIDES ARIS N   +2 more
openaire   +4 more sources

ACVR1 and Fibrodysplasia Ossificans Progressiva

2016
Frederick S. Kaplan, O. W. Towler, Eileen M. Shore   +2 more
openaire   +1 more source

Faculty Opinions recommendation of ACVR1 antibodies exacerbate heterotopic ossification in fibrodysplasia ossificans progressiva (FOP) by activating FOP-mutant ACVR1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature, 2022
openaire   +1 more source