Results 161 to 170 of about 5,020 (198)
Immunogenomic profiling reveals targets for gene therapy in pediatric brain tumors. [PDF]
Neurooncol AdvRovesti G +13 more
europepmc +1 more source
Rechallenge of ruxolitinib after momelotinib-related toxicity in a 74-yo woman with secondary myelofibrosis: a case report. [PDF]
Front Med (Lausanne)Torregrosa Diaz JM +4 more
europepmc +1 more source
Neofunction of ACVR1 in fibrodysplasia ossificans progressiva
Neofunction of ACVR1 in fibrodysplasia ossificans progressivaopenaire +1 more source
Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas [PDF]
Cancer Cell, 2020 Diffuse intrinsic pontine gliomas (DIPGs) are aggressive pediatric brain tumors for which there is currently no effective treatment. Some of these tumors combine gain-of-function mutations in ACVR1, PIK3CA, and histone H3-encoding genes.
Alex N Bullock +2 more
exaly +2 more sources
The Type I BMP Receptor ACVR1/ALK2 Is Required for Chondrogenesis During Development [PDF]
Journal of Bone and Mineral Research, 2015 Bone morphogenetic proteins (BMPs) are crucial regulators of chondrogenesis. BMPs transduce their signals through three type I receptors: BMPR1A, BMPR1B, and ACVR1/ALK2.
Karen Lyons +2 more
exaly +2 more sources
Investigative Ophthalmology and Visual Science, 2008 PURPOSE: Bone morphogenetic protein (BMP) signaling is essential for the induction and subsequent development of the lens. The purpose of this study was to analyze the function(s) of the type 1 BMP receptor, Acvr1, in lens development. METHODS: Acvr1 was
Erwin P Bottinger +2 more
exaly +2 more sources