Results 11 to 20 of about 48,268 (218)

The Role of Metabolites in Acyclovir-Induced Neurotoxicity and Nephrotoxicity [PDF]

open access: yesMedicines
Acyclovir is an antiviral drug effective against infections caused by herpes simplex and varicella zoster viruses. It is given intravenously to treat serious infections such as herpes encephalitis.
Asma Aboelezz, Sherif Hanafy Mahmoud
doaj   +2 more sources

Two cases of a pharmacokinetic interaction between (val)acyclovir and mycophenolate mofetil

open access: yesClinical Infection in Practice, 2023
Background: Administration of (val)acyclovir in combination with mycophenolate mofetil (MMF) can result in increased acyclovir plasma levels due to competition with acyclovir for renal tubular secretion.
F.A. Berger   +2 more
doaj   +1 more source

Effectiveness of acyclovir in the treatment of pityriasis rosea. A systematic review and meta-analysis [PDF]

open access: yesAnais Brasileiros de Dermatologia, 2018
: Background: There is a lack of evidence to support acyclovir administration in pityriasis rosea. Objective: To determine the efficacy of acyclovir in patients with typical pityriasis rosea.
Milton Rodriguez-Zuniga   +2 more
doaj   +1 more source

Acyclovir-induced glomerulonephritis in a 40-year-old woman without medical history: a case report

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Well-known side effects of acyclovir are nephrotoxicity and neurotoxicity. We present a 49-year-old woman without pre-existing renal failure, with an acute kidney injury and encephalopathy. Since there was a clear correlation with the intake of acyclovir
Marie-Justine Desrumaux   +2 more
doaj   +1 more source

Incidence, patterns, risk factors and clinical outcomes of intravenous acyclovir induced nephrotoxicity

open access: yesSaudi Pharmaceutical Journal, 2022
Objectives: Acyclovir is approved to treat herpes simplex virus (HSV) type 1, type 2 and varicella-zoster virus. It is mainly eliminated via the kidneys, for which drug crystals accumulation might lead to nephrotoxicity. This study aimed to determine the
Abdullah M. Al-Alawi   +4 more
doaj   +1 more source

Acyclovir crystalluria: The utility of bedside urine routine microscopic examination

open access: yesJournal of Pediatric Critical Care, 2020
Acyclovir, an acyclic nucleoside, is commonly used for the treatment of viral infections. Acyclovir is well tolerated in children. However, severe nephrotoxicity has been shown to occur in some children.
Puneet Jain   +3 more
doaj   +1 more source

Neonates with acute liver failure have higher overall mortality but similar posttransplant outcomes as older infants

open access: yesLiver Transplantation, EarlyView., 2022
Abstract Neonatal acute liver failure (ALF) carries a high mortality rate; however, little data exist on its peritransplant hospital course. This project aimed to identify factors associated with outcomes in neonates with ALF using large multicenter databases.
Swati Antala   +6 more
wiley   +1 more source

IN VITRO COMPARATIVE OF DIFFERENT ACYCLOVIR TABLET [PDF]

open access: yesBasrah Journal of Veterinary Research, 2012
The aim of the study was to compare the in vitro performance of different acyclovir tablets of the same strength from different companies under different trade names: Acyclovir actavis 400mg tab ,Acic 400mg tab ,and Veramide 400mg tab., and compare with ...
Nadheerah Falih Neamah
doaj   +1 more source

Shedding a Light on Acyclovir Pharmacodynamics: A Retrospective Analysis on Pharmacokinetic/Pharmacodynamic Modelling of Acyclovir for the Treatment of Varicella Zoster Virus Infection in Immunocompromised Patients: A Pilot Study

open access: yesPharmaceutics, 2022
Background: Acyclovir and valacyclovir are used for the treatment and prophylaxis of infections with herpes simplex virus (HSV) and varicella zoster virus (VZV). The aim of this study is to provide insight into the pharmacodynamics (PD) of (val)acyclovir.
Geeske F. Grit   +4 more
doaj   +1 more source

Acyclovir induced hypokalemia [PDF]

open access: yesJournal of Clinical Virology, 2013
Intravenous (IV) acyclovir, a mainstay antiviral for herpesviruses, may cause crystalluria and lead to acute kidney injury.1 Acyclovir has been associated with lower levels of potassium in canines but acyclovir induced hypokalemia has been reported only once in humans as part of a large adverse drug reaction monitoring program.2,3 A patient with a ...
Paul E, Drawz   +2 more
openaire   +2 more sources

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