Results 31 to 40 of about 28,279 (174)

Acute renal and neurotoxicity due to weight-based dosing of intravenous acyclovir: How to dose in obese patients?

Clinical Infection in Practice, 2020
Background: Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing.
Bastiaan TGM Sallevelt, Erin H Smeijsters, Toine CG Egberts, Kim CM van der Elst, Tania Mudrikova   +4 more
doaj   +1 more source

Synthesis, Characterization and Safety Evaluation of Sericin-Based Hydrogels for Controlled Delivery of Acyclovir

Pharmaceuticals, 2021
Conventional formulations of antiviral drug acyclovir have various limitations such as low bioavailability. The current study was aimed at developing polymeric matrices for the controlled delivery of acyclovir using sericin as polymer and acrylic acid ...
Moawia M. Al-Tabakha, Shujaat Ali Khan, Akram Ashames, Hamid Ullah, Kaleem Ullah, Ghulam Murtaza, Nageeb Hassan   +6 more
doaj   +1 more source

Do consumers and healthcare professionals report the same adverse event differently? A paired analysis of duplicate vaccine safety reports in Norway

British Journal of Clinical Pharmacology, EarlyView.
Aim This study aimed to compare how Norwegian healthcare professionals (HCPs) and consumers reported the same adverse event (AE) following immunization with vaccines against COVID‐19 during the COVID‐19 pandemic. Specifically, we aimed to compare the extent to which HCPs and consumers reported information relevant for assessing the causal relationship ...
Tommy Emil Dzus, Johaina Sarrage, Hilde Samdal, François Montastruc, Elena Rocca   +4 more
wiley   +1 more source

Acyclovir in bipolar disorder: A mismatched combination?

Indian Journal of Psychological Medicine, 2011
Acyclovir, a commonly used antiviral drug can rarely result in neuropsychiatric complications especially in elderly. We for the first time report acyclovir associated hypomania in an elderly woman.
Naveen Jayaram, Naren P Rao, Ganesan Venkatasubramanian, S Sanmuganathan, Rishikesh V Behere, Shivaram Varambally, Bangalore N Gangadhar   +6 more
doaj   +1 more source

Recent Advances in Pickering Emulsion Templated Phase Change Material Microcapsules: Design, Fabrication, and Multifunctional Applications

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
Fabrication process of phase change microcapsules using a Pickering emulsion template method and their subsequent applications. The increasing demand for efficient thermal energy storage systems has driven the development of phase change material microcapsules (PCMMs), which provide high energy‐storage density, reversible phase change, and reduced ...
Ziyan Li, Jinsheng Sun, Kaihe Lv, Chaozheng Liu, Meichun Li   +4 more
wiley   +1 more source

Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct

Journal of Neuroinflammation, 2010
Regulatory T cells, Tregs, are a subset of lymphocytes that have immunosuppressive attributes. They are elevated in blood of glioblastoma patients and within this tumor's tissue itself. Indoleamine 2,3-dioxygenase, IDO, converts tryptophan to kynurenine.
Söderlund Johan, Erhardt Sophie, Kast Richard E   +2 more
doaj   +1 more source

Cenobamate use in super‐refractory status epilepticus: A report of three cases

Epileptic Disorders, EarlyView.
Abstract Objectives Super‐refractory status epilepticus (SRSE) is a neurological emergency with high morbidity and mortality. Cenobamate, a novel antiseizure medication, may be helpful in managing SRSE, but evidence is limited. Methods This retrospective case series reports the use of cenobamate as add‐on therapy in the management of three cases of ...
Marina Romozzi, Juan Luis Alcala‐Zermeno, Antonio Funcis, Federico Tosto, Marta Piccioli, Luigi Francesco Iannone, Riccardo Maviglia, Masahito Katsuki, Yasuhiko Matsumori, Paolo Calabresi, Raffaele Iorio, Catello Vollono   +11 more
wiley   +1 more source

Possible Protective Role of Quercetin on Acyclovir-Induced Renal Injury in Adult Male Albino Rats

Arcades of Medicine
Background: Acyclovir is an effective antiviral drug; however, its clinical use is limited by nephrotoxic side effects. This study explores the potential protective role of Quercetin against Acyclovir-induced renal injury in adult male albino rats, using
Nour Eldin Mohamed, Azza Abdou Hussein, Shereen Youssef, Gamal Elsayed   +3 more
doaj   +1 more source

Acute kidney injury, secondary to valacyclovir use during pregnancy for the prevention of fetal cytomegalovirus infection

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract High dose valacyclovir treatment of pregnant women has become a common treatment for primary CMV infection, to prevent vertical transmission to the fetus. We present a case of a healthy young pregnant female with primary CMV infection during the first trimester who was diagnosed with acute kidney injury secondary to valacyclovir treatment ...
Jason Brafman, Yechiel Schlesinger, Moshe Barg, Shmuel Benenson   +3 more
wiley   +1 more source

A simple method for the determination of acyclovir concentrations in human plasma using high-performance liquid chromatography

Future Journal of Pharmaceutical Sciences
Background Acyclovir is an anti-viral medication given to treat herpes simplex and herpes zoster infection. In some severe conditions such as herpes encephalitis, acyclovir is administered intravenously.
Asma Aboelezz, Maged Kharouba, Sherif Hanafy Mahmoud   +2 more
doaj   +1 more source