Results 31 to 40 of about 28,057 (98)

Acute renal and neurotoxicity due to weight-based dosing of intravenous acyclovir: How to dose in obese patients?

Clinical Infection in Practice, 2020
Background: Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing.
Bastiaan TGM Sallevelt, Erin H Smeijsters, Toine CG Egberts, Kim CM van der Elst, Tania Mudrikova   +4 more
doaj   +1 more source

A Randomized, Double-blind, Placebo-Controlled Study of Efficacy of Oral Acyclovir in the Treatment of Pityriasis Rosea [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Pityriasis rosea is an acute self-limiting skin disorder of unknown aetiology. Recently human herpes virus 6 and 7 has been hypothesized to be the cause of pityriasis rosea. Objective: To determine the efficacy of acyclovir, an anti-viral
Satyaki Ganguly
doaj   +1 more source

Sustained release of acyclovir from alginate-gellan gum and alginate-xanthan gum microbeads

JCIS Open
In the current research, acyclovir-loaded microbeads were formulated via ionotropic gelation using sodium alginate-gellan gum and sodium alginate-xanthan gum. In the preparation of these acyclovir-loaded microbeads, aluminium chloride and barium chloride
Sudipta Das, Arnab Samanta, Sawan Das, Amit Kumar Nayak   +3 more
doaj   +1 more source

Pharmacokinetic and Efficacy Study of Acyclovir Against Cyprinid Herpesvirus 3 in Cyprinus carpio

Frontiers in Veterinary Science, 2020
Cyprinid Herpesvirus 3 (CyHV-3), more commonly known as Koi Herpesvirus (KHV), is a re-emergent virus causing acute systemic infection with high mortality rates in koi fish (Cyprinus carpio).
Eva Marie Quijano Cardé, Zeinab Yazdi, Susan Yun, Ruixue Hu, Heather Knych, Denise M. Imai, Esteban Soto   +6 more
doaj   +1 more source

Pseudoboehmite as a drug delivery system for acyclovir

Scientific Reports, 2021
Herpes simplex virus is among the most prevalent sexually transmitted infections. Acyclovir is a potent, selective inhibitor of herpes viruses and it is indicated for the treatment and management of recurrent cold sores on the lips and face, genital ...
Renato Meneghetti Peres, Jéssica Maiara Leme Sousa, Mariana Oliva de Oliveira, Maura Vincenza Rossi, Rene Ramos de Oliveira, Nelson Batista de Lima, Ayrton Bernussi, Juliusz Warzywoda, Bruno Sarmento, Antonio Hortencio Munhoz   +9 more
doaj   +1 more source

Acyclovir in bipolar disorder: A mismatched combination?

Indian Journal of Psychological Medicine, 2011
Acyclovir, a commonly used antiviral drug can rarely result in neuropsychiatric complications especially in elderly. We for the first time report acyclovir associated hypomania in an elderly woman.
Naveen Jayaram, Naren P Rao, Ganesan Venkatasubramanian, S Sanmuganathan, Rishikesh V Behere, Shivaram Varambally, Bangalore N Gangadhar   +6 more
doaj   +1 more source

Synthesis, Characterization and Safety Evaluation of Sericin-Based Hydrogels for Controlled Delivery of Acyclovir

Pharmaceuticals, 2021
Conventional formulations of antiviral drug acyclovir have various limitations such as low bioavailability. The current study was aimed at developing polymeric matrices for the controlled delivery of acyclovir using sericin as polymer and acrylic acid ...
Moawia M. Al-Tabakha, Shujaat Ali Khan, Akram Ashames, Hamid Ullah, Kaleem Ullah, Ghulam Murtaza, Nageeb Hassan   +6 more
doaj   +1 more source

Possible Protective Role of Quercetin on Acyclovir-Induced Renal Injury in Adult Male Albino Rats

Arcades of Medicine
Background: Acyclovir is an effective antiviral drug; however, its clinical use is limited by nephrotoxic side effects. This study explores the potential protective role of Quercetin against Acyclovir-induced renal injury in adult male albino rats, using
Nour Eldin Mohamed, Azza Abdou Hussein, Shereen Youssef, Gamal Elsayed   +3 more
doaj   +1 more source

Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct

Journal of Neuroinflammation, 2010
Regulatory T cells, Tregs, are a subset of lymphocytes that have immunosuppressive attributes. They are elevated in blood of glioblastoma patients and within this tumor's tissue itself. Indoleamine 2,3-dioxygenase, IDO, converts tryptophan to kynurenine.
Söderlund Johan, Erhardt Sophie, Kast Richard E   +2 more
doaj   +1 more source

A simple method for the determination of acyclovir concentrations in human plasma using high-performance liquid chromatography

Future Journal of Pharmaceutical Sciences
Background Acyclovir is an anti-viral medication given to treat herpes simplex and herpes zoster infection. In some severe conditions such as herpes encephalitis, acyclovir is administered intravenously.
Asma Aboelezz, Maged Kharouba, Sherif Hanafy Mahmoud   +2 more
doaj   +1 more source