Results 31 to 40 of about 36,344 (217)

Electrospun Structural Hybrids of Acyclovir-Polyacrylonitrile at Acyclovir for Modifying Drug Release

open access: yes, 2021
In traditional pharmaceutics, drug–crystalline nanoparticles and drug–polymer composites are frequently explored for their ability to modify drug release profiles.
Yonghui Wu   +5 more
core   +1 more source

Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity. [PDF]

open access: yesPLoS ONE, 2015
Immune mediated adverse drug reactions (IM-ADRs) remain a significant source of patient morbidity that have more recently been shown to be associated with specific class I and/or II human leukocyte antigen (HLA) alleles. Abacavir-induced hypersensitivity
Imir G Metushi   +15 more
doaj   +1 more source

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

open access: yesFrontiers in Microbiology, 2019
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis   +5 more
doaj   +1 more source

Acyclovir-induced neurotoxicity with a positive cerebrospinal fluid varicella zoster PCR result creating a management dilemma: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Varicella zoster virus central nervous system infections can present as aseptic meningitis, encephalitis, myelitis, and vasculopathy.
Kelli M. Robertson   +2 more
doaj   +1 more source

Pharmacokinetics and analytical determination of acyclovir in Asian elephant calves (Elephas maximus)

open access: yesVeterinary and Animal Science, 2022
A therapeutic regimen that includes antiviral drugs is critical for the survival of Asian elephant (Elephas maximus) calves infected with elephant endotheliotropic herpesvirus hemorrhagic disease (EEHV-HD), with acyclovir showing considerable promise ...
Siripat Khammesri   +6 more
doaj   +1 more source

Comparison of some physical parameters of different brands of acyclovir tablets marketed in Iran: Quality control of acyclovir tablets

open access: yes, 2022
Acyclovir is the nucleoside analogue of guanosine, which is used as an antiviral drug. Since the quality requirements set for a higher quality product are necessary, the purpose of this study was to investigate the quality control characteristics of ...
Zarepishe, Naeime   +4 more
core   +1 more source

In vitro antiviral activity of thymoquinone and its synergistic effect with acyclovir against herpes simplex virus type 1 (HSV-1) [PDF]

open access: yesJournal of HerbMed Pharmacology
Introduction: Drug resistance has heightened the demand for natural antiviral agents. Thymoquinone (TQ), a major bioactive component of black seed oil, has demonstrated antiviral activity in numerous studies.
Maryam Shirian   +5 more
doaj   +1 more source

FLUOROMETRIC•DETERMINATION OF ACYCLOVIR IN SPIKED HUMAN PLASMA [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1993
A highly sensitive fluorometric method for determination of acyclovir  is described. The method depends  on the interaction between acyclovir .and 7-hydroxy-4-methylcoumarin where a fluorophore of high fluorogenic activity is formed which has wavelengths
M. Mabrouk, A. Habeeb
doaj   +1 more source

Bullous eruptions in a preschool child: A rare adverse effect of acyclovir

open access: yesIndian Journal of Paediatric Dermatology, 2020
Acyclovir in children is usually associated with minimal local adverse effects, with bullous eruptions being extremely rare in occurrence. A 5-year-old boy was admitted to the pediatric intensive care unit as a case of febrile encephalopathy with status ...
Nidhi Garg, K V Vinu Balraam
doaj   +1 more source

Pharmacokinetics of Stereoisomeric Dipeptide Prodrugs of Acyclovir Following Intravenous and Oral Administrations in Rats: A Study Involving In vivo Corneal Uptake of Acyclovir Following Oral Dosing

open access: yes, 2009
Objective: To delineate the plasma pharmacokinetics and determine the corneal uptake of valine based stereoisomeric dipeptide prodrugs of acyclovir (ACV) in rats. Methods: Male Sprague-Dawley rats were used for the study.
Ripal Gaudana   +4 more
core   +1 more source

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