Results 51 to 60 of about 28,057 (98)

The incidence, risk factors, and clinical outcomes of acute kidney injury (staged using the RIFLE classification) associated with intravenous acyclovir administration

Renal Failure, 2018
Intravenous (IV) acyclovir is commonly administered medication for viral infection but is well known for its nephrotoxicity. However, there was no study for incidence, risk factors, and clinical outcomes of acute kidney injury (AKI) associated with IV ...
Eun Ju Lee, Ha Nee Jang, Hyun Seop Cho, Eunjin Bae, Tae Won Lee, Se-Ho Chang, Dong Jun Park   +6 more
doaj   +1 more source

Employing a PLGA-TPGS based nanoparticle to improve the ocular delivery of Acyclovir

Saudi Pharmaceutical Journal, 2019
Delivering drugs via the ocular route has always been a challenge for poorly soluble drugs. The various anatomical and physiological barriers in the eye cavity hinder the residence of drugs within the corneal and precorneal regions.
Musaed Alkholief, Hammam Albasit, Adel Alhowyan, Sultan Alshehri, Mohammad Raish, Mohd Abul Kalam, Aws Alshamsan   +6 more
doaj   +1 more source

Antiviral-Resistant Fulminant Herpes Hepatitis in Pregnancy

American Journal of Perinatology Reports, 2013
Fulminant herpes hepatitis with disseminated extrahepatic involvement in pregnancy is rare and carries a high mortality risk. Although acyclovir remains standard first-line therapy, effective management of acyclovir-resistant disseminated herpes simplex ...
Christina A. Herrera, Kacey Y. Eichelberger, Nancy C. Chescheir   +2 more
doaj   +1 more source

Antiviral and virucidal activity of Chelidonium majus L. extract compared with Acyclovir against Herpes simplex virus type 1

Armaghane Danesh Bimonthly Journal, 2017
Background and aim: Herpes simplex virus is one of the most important human pathogenic viruses that may lead to oral herpes, keratoconjunctivitis and even encephalitis.
M Sadeghpour Natanzi, M Parsania, M Aminzadeh   +2 more
doaj  

Effects of aqueous leaf extract of Telfairia occidentalis on acyclovir induced renal damage in adult Wistar rat

Journal of Applied Sciences and Environmental Management
This study investigated the effects of aqueous leaf extract of Telfairia Occidentalis on acyclovir-induced renal damage in the kidneys of adult Wistar rats. A total of thirty adult Wistar rats weighing an average of 200g were used for this study.
A. R. O. Ehimigbai, D. T. Jayeola
doaj  

Exploring the Effectiveness of Acyclovir against Ranaviral Thymidine Kinases: Molecular Docking and Experimental Validation in a Fish Cell Line

Life
The effectiveness of acyclovir, a selective anti-herpesvirus agent, was tested both in silico and in vitro against two ranaviruses, namely the European catfish virus (ECV) and Frog virus 3 (FV3).
Richárd Rácz, Ákos Gellért, Tibor Papp, Andor Doszpoly   +3 more
doaj   +1 more source

Acyclovir-resistant herpetic keratitis in a solid-organ transplant recipient on systemic immunosuppression

Clinical Ophthalmology, 2013
Liam Daniel Turner,1 Peter Beckingsale1,2,31Princess Alexandra Hospital; 2Terrace Eye Centre; 3Laser Sight, Brisbane, Queensland, AustraliaPurpose: To report a case of acyclovir-resistant herpetic keratitis in a solid-organ lung transplant recipient that
Turner LD, Beckingsale P
doaj  

The efficacy of acyclovir in treatment of the pemphigus vulgaris

Journal of Research in Medical Sciences, 2013
Background: Pemphigus is a group of autoimmune blistering diseases of the skin and mucous membranes caused by the presence of antibodies against adhesion molecules on the cell surface of keratinocytes.
Fariba Iraji, Gita Faghihi, Amir Hossein Siadat   +2 more
doaj  

Neonatal Varicella-Zoster Virus Meningitis Without Pleocytosis: Diagnostic Value of Polymerase Chain Reaction. [PDF]

Cureus
Boulfouyoul A, Ettoini K, Oulmaati A.
europepmc   +1 more source

Repurposing Purine Analog Antivirals to Modulate Serum Uric Acid: Evidence From Real-World Data. [PDF]

Clin Transl Sci
Magagnoli J, Cummings TH, Wyatt MD, McInnes C, Ambati J, Sutton SS.   +5 more
europepmc   +1 more source