Results 51 to 60 of about 36,344 (217)

Acyclovir for treating varicella in otherwise healthy children and adolescents: a systematic review of randomised controlled trials. [PDF]

open access: yes, 2002
Background Acyclovir has the potential to shorten the course of chickenpox which may result in reduced costs and morbidity. We conducted a systematic review of randomised controlled trials that evaluated acyclovir for the treatment of chickenpox in ...
Hartling, L.   +3 more
core   +1 more source

Pharmacokinetic and Efficacy Study of Acyclovir Against Cyprinid Herpesvirus 3 in Cyprinus carpio

open access: yesFrontiers in Veterinary Science, 2020
Cyprinid Herpesvirus 3 (CyHV-3), more commonly known as Koi Herpesvirus (KHV), is a re-emergent virus causing acute systemic infection with high mortality rates in koi fish (Cyprinus carpio).
Eva Marie Quijano Cardé   +6 more
doaj   +1 more source

The safe and effective use of tofacitinib and ustekinumab combination therapy in infantile onset inflammatory bowel disease

open access: yesJPGN Reports, EarlyView.
Abstract Infantile‐onset inflammatory bowel disease (IOIBD) is a rare and severe subset of very‐early‐onset IBD, often associated with immune dysregulation and poor response to conventional therapies. Data regarding the use of Janus kinase inhibitors (JAKI) in this population is limited.
Smridhi Mahajan   +2 more
wiley   +1 more source

Acyclovir resistance in herpes simplex encephalitis.

open access: yes, 2010
Herpes simplex virus type 1 is a common cause of severe sporadic encephalitis. Treatment with acyclovir is highly effective in this disease. We report the case of a 27-year-old, immunocompetent woman with acyclovir-resistant herpes simplex encephalitis ...
Schulte, EC;Sauerbrei, A;Hoffmann, D;Zimmer, C;Hemmer, B;Muhlau, M
core   +1 more source

Synthesis, Characterization and Safety Evaluation of Sericin-Based Hydrogels for Controlled Delivery of Acyclovir

open access: yesPharmaceuticals, 2021
Conventional formulations of antiviral drug acyclovir have various limitations such as low bioavailability. The current study was aimed at developing polymeric matrices for the controlled delivery of acyclovir using sericin as polymer and acrylic acid ...
Moawia M. Al-Tabakha   +6 more
doaj   +1 more source

Bevacizumab‐Associated Eczema Herpeticum in Metastatic Ovarian Carcinoma: A Case Report

open access: yesJEADV Clinical Practice, EarlyView.
ABSTRACT Eczema herpeticum (EH) is a rare but potentially life‐threatening cutaneous infection caused by herpes simplex virus (HSV), classically associated with atopic dermatitis. Its occurrence in oncology patients receiving anti‐angiogenic targeted therapy and cytotoxic chemotherapy is exceedingly uncommon.
Mandeep Dutta Joshi   +6 more
wiley   +1 more source

Acyclovir and postherpetic neuralgia.

open access: yes, 2016
Studies have demonstrated the benefit of acyclovir, given intravenously or orally, on the acute illness in herpes zoster (HZ). Whether or not such treatment influences the subsequent development of postherpetic neuralgia (PHN) has been the subject of ...

core   +1 more source

Possible Protective Role of Quercetin on Acyclovir-Induced Renal Injury in Adult Male Albino Rats

open access: yesArcades of Medicine
Background: Acyclovir is an effective antiviral drug; however, its clinical use is limited by nephrotoxic side effects. This study explores the potential protective role of Quercetin against Acyclovir-induced renal injury in adult male albino rats, using
Nour Eldin Mohamed   +3 more
doaj   +1 more source

Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct

open access: yesJournal of Neuroinflammation, 2010
Regulatory T cells, Tregs, are a subset of lymphocytes that have immunosuppressive attributes. They are elevated in blood of glioblastoma patients and within this tumor's tissue itself. Indoleamine 2,3-dioxygenase, IDO, converts tryptophan to kynurenine.
Söderlund Johan   +2 more
doaj   +1 more source

Acute renal and neurotoxicity due to weight-based dosing of intravenous acyclovir: How to dose in obese patients?

open access: yesClinical Infection in Practice, 2020
Background: Acyclovir is a hydrophilic drug that is mainly distributed in the lean compartments of the body. Consequently, dosing on total body weight in obese patients may lead to drug overdosing.
Bastiaan TGM Sallevelt   +4 more
doaj   +1 more source

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