Results 41 to 50 of about 28,057 (98)

Herpes Simplex Virus Type 1 Clinical Isolates Respond to UL29-Targeted siRNA Swarm Treatment Independent of Their Acyclovir Sensitivity

Viruses, 2020
Acyclovir is the drug of choice for the treatment of herpes simplex virus (HSV) infections. Acyclovir-resistant HSV strains may emerge, especially during long-term drug use, and subsequently cause difficult-to-treat exacerbations. Previously, we set up a
Kiira Kalke, Jenni Lehtinen, Jelena Gnjatovic, Liisa M. Lund, Marie C. Nyman, Henrik Paavilainen, Julius Orpana, Tuomas Lasanen, Fanny Frejborg, Alesia A. Levanova, Tytti Vuorinen, Minna M. Poranen, Veijo Hukkanen   +12 more
doaj   +1 more source

Acyclovir Nephrotoxicity: A Case Report Highlighting the Importance of Prevention, Detection, and Treatment of Acyclovir-Induced Nephropathy

Case Reports in Medicine, 2010
Acute kidney injury is an unfortunate complication of acyclovir therapy secondary to crystal-induced nephropathy. It is characterized by a decrease in renal function that develops within 24–48 hours of acyclovir administration indicated by a rapid rise ...
Raymond Fleischer, Michael Johnson
doaj   +1 more source

The effects of oral Acyclovir in the treatment of necrotizing Herpetic keratouveitis [PDF]

Acta Medica Iranica, 2000
This study was conducted to evaluate the effects of administering oral acyclovir in conjunction with topical acyclovir and steroids in the treatment of necrotizing herpetic keratouveitis.
"Hosseini Tehrani M;Poormostadam B;Vallaei N;Raiszadeh F "
doaj   +1 more source

A Comparative Study to Evaluate the Efficacy and Safety of Acyclovir and Famciclovir in the Management of Herpes Zoster [PDF]

Journal of Clinical and Diagnostic Research, 2013
Background: Over the years, acyclovir has been the oral antiviral agent approved for the treatment of patients with acute herpes zoster,Its effectiveness in lessening the acute signs and symptoms of herpes zoster has been established but the effects ...
M.G. GOPAL, SHANNOMA, SHARATH KUMAR B.C., RAMESH M., NANDINI A.S., NAMRATA C. MANJUNATH   +5 more
doaj   +1 more source

Improvement of physicochemical parameters of acyclovir using cocrystallization approach

Brazilian Journal of Pharmaceutical Sciences
Acyclovir is an antiviral drug having potent activity against the virus of herpes family and varicella zoster. Unfortunately, drug suffers very poor oral bioavailability (15-30%).
Jignasa Ketan Savjani, Chirag Pathak
doaj   +1 more source

The use of nerve growth factor in herpetic keratitis: a case report

Journal of Medical Case Reports, 2007
Background We evaluate the role of nerve growth factor (NGF) eye drops to treat a herpetic corneal ulcer resistant to systemic and local acyclovir treatment in an HIV-positive patient.
Cellini Mauro, Leonetti Pietro, Campos Emilio C   +2 more
doaj   +1 more source

Crystal structure and supramolecular assembly of the ionic liquid-like salt tributylmethylammonium acyclovir ([N4,4,4,1][Acy])

Journal of Ionic Liquids
In search of low melting, ionic liquid-like forms of the active pharmaceutical ingredient (API), acyclovir, we isolated tributylmethylammonium acyclovir ([N4,4,4,1][Acy]) and structurally characterized it by single crystal X-ray diffraction.
Sophia L. Sagala, Julia L. Shamshina, Robin D. Rogers   +2 more
doaj   +1 more source

Acyclovir-induced sinus bradycardia: a case report and literature review [PDF]

Encephalitis
In this report, we describe the case of a 51-year-old female who presented to our emergency department with varicella zoster infection. Her relevant medical history included rheumatoid arthritis which was treated with risankizumab.
Gregory Mikerov, Ilyse Darwish, Gail Goldman   +2 more
doaj   +1 more source

Empirical treatment with parenteral acyclovir in a child with herpes simplex virus hepatitis and acute lymphoblastic leukemia

IDCases, 2018
Introduction: Hepatitis secondary to Herpes Simplex Virus (HSV) infection is a complication that often leads to fatal hepatic failure. Early treatment with the anti-viral drug, acyclovir, is life-saving.
Nesreen A. Faqih, Mahmoud A. Alfaqih, Khadra Salami, Brian Herron, Iyad Sultan, Maysa Al-Hussaini   +5 more
doaj   +1 more source

Low-Dose Acyclovir Prophylaxis for Varicella zoster Reactivation in Autologous Hematopoietic Cell Transplantation Recipients

Clinical Hematology International, 2019
Varicella zoster virus (VZV) reactivation after autologous hematopoietic cell transplantation (auto-HCT) may be observed in a quarter of patients.
Naomi Fei, Nilay Shah, Aaron Cumpston, Sijin Wen, Kelly G. Ross, Michael Craig, Abraham S. Kanate   +6 more
doaj   +1 more source