Results 41 to 50 of about 36,344 (217)

The Role of Metabolites in Acyclovir-Induced Neurotoxicity and Nephrotoxicity

Medicines
Acyclovir is an antiviral drug effective against infections caused by herpes simplex and varicella zoster viruses. It is given intravenously to treat serious infections such as herpes encephalitis.
Asma Aboelezz, Sherif Hanafy Mahmoud
doaj   +1 more source

Effects of Acyclovir on the Cerebellar Cortex of Adult Male Albino Rats And The Protective Effect Of Zinc Sulfate (Histological and Immunohistochemical Study)

SVU - International Journal of Medical Sciences
Background: Acyclovir is an antiviral drug. for the treatment of systemic herpes infections and central nervous system infections. Zinc is a vital mineral that found in foods and consumed as a dietary supplement.
Asmaa Sabry Bassit , Bothina Zakria Elsayed , Ahlam Wagih Mohamed   +2 more
doaj   +1 more source

Circulating Exosomes Drive Persistent Neuronal Dysfunction in Post‐Herpetic Neuralgia Patients

Annals of Neurology, EarlyView.
Proposed model of exosome‐mediated neuronal dysfunction in post‐herpetic neuralgia (PHN). (1) Circulating, non‐pathogenic exosomes maintain homeostatic processes in healthy skin, where sensory nerve fibers innervate the epidermis and dermis. (2) During acute zoster, reactivating varicella zoster virus (VZV) travels down neurites to the skin causing ...
Christy S. Niemeyer, Seth Frietze, Serena W.R. Lewis, Emily C. Artman, Christina Coughlan, Safa I. Vaseemuddin, Arianna Gentile Polese, Maria A. Nagel, Stephen K. Tyring, Fyona Okundia, Anthony J. Saviola, Gary C. Curhan, Sharon G. Curhan, Diego Restrepo, Andrew N. Bubak   +14 more
wiley   +1 more source

Acyclovir induced nephropathy : a case report [PDF]

, 2013
Acyclovir is frequently used in the management of suspected or proven serious viral infections in children. Despite its good safety profile serious side effects are known to occur.
Vella, Cecil
core  

A Randomized, Double-blind, Placebo-Controlled Study of Efficacy of Oral Acyclovir in the Treatment of Pityriasis Rosea [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Pityriasis rosea is an acute self-limiting skin disorder of unknown aetiology. Recently human herpes virus 6 and 7 has been hypothesized to be the cause of pityriasis rosea. Objective: To determine the efficacy of acyclovir, an anti-viral
Satyaki Ganguly
doaj   +1 more source

Current practice and guideline adherence in renal dose adjustment for patients with chronic kidney disease: A systematic review and meta‐analysis

British Journal of Clinical Pharmacology, EarlyView.
Aims To quantify prescribing adherence to renal dosing recommendations in adults with chronic kidney disease (CKD; Stage 3 and above) and to evaluate the clinical consequences of non‐adherence. Methods This systematic review and meta‐analysis was conducted in accordance with PRISMA 2020 guidelines and registered in PROSPERO (CRD42025620883).
Hager ElGeed, Ahmed Tehemar, Mohamed Gasimelseed, Ahmed Gharaibeh, Muhammad Abdul Hadi, Kazeem Yusuff, Amani Zidan, Ahmed Awaisu   +7 more
wiley   +1 more source

Acyclovir-induced neurotoxicity: concentration-side effect relationship in acyclovir overdose.

, 1993
PURPOSE To investigate the concentration-side effect relationship in a patient with severe acyclovir-induced neurotoxicity and to summarize the information available in the literature about central nervous system side effects due to acyclovir.
Ritz RF, Haefeli WE, Schoenenberger RA, Weiss P   +3 more
core   +1 more source

Sustained release of acyclovir from alginate-gellan gum and alginate-xanthan gum microbeads

JCIS Open
In the current research, acyclovir-loaded microbeads were formulated via ionotropic gelation using sodium alginate-gellan gum and sodium alginate-xanthan gum. In the preparation of these acyclovir-loaded microbeads, aluminium chloride and barium chloride
Sudipta Das, Arnab Samanta, Sawan Das, Amit Kumar Nayak   +3 more
doaj   +1 more source

A case series of necrotizing periodontal diseases in hospitalized patients: What hasn't been said yet?

Clinical Advances in Periodontics, EarlyView.
Abstract Background Necrotizing periodontal diseases (NPDs) are uncommon and severe inflammatory conditions characterized by tissue necrosis, painful ulceration, and rapid clinical progression, frequently associated with systemic immunosuppression. Limited data exist regarding their clinical presentation and management in hospital settings.
Osmaria Letthycia Carvalho Leal, Fernanda Bortolotto, Mariana Cristina Manoel, Gabriela Silveira de Araújo, Ana Carolina Fragoso Motta, Leandro Dorigan de Macedo, Lara Maria Alencar Ramos Innocentini, Joab Cabral Ramos, Isabel Schausltz Pereira Faustino   +8 more
wiley   +1 more source

Chemical Stability of New Acyclovir Analogues with Peptidomimetics

, 2011
In the search for new and effective prodrugs against the herpes simplex virus, a series of acyclovir analogues with a thiazole ring containing amino acids (glycine, alanine, valine, leucine) has been investigated.
Ivanka STANKOVA, Georgi HRISTOV
core   +1 more source