Results 21 to 30 of about 28,057 (98)

Vitreous pharmacokinetics and electroretinographic findings after intravitreal injection of acyclovir in rabbits

open access: yesClinics, 2012
OBJECTIVES: Acute retinal necrosis is a rapidly progressive and devastating viral retinitis caused by the herpesvirus family. Systemic acyclovir is the treatment of choice; however, the progression of retinal lesions ceases approximately 2 days after ...
Francisco Max Damico   +8 more
doaj   +1 more source

Acyclovir Has Low but Detectable Influence on HLA-B*57:01 Specificity without Inducing Hypersensitivity. [PDF]

open access: yesPLoS ONE, 2015
Immune mediated adverse drug reactions (IM-ADRs) remain a significant source of patient morbidity that have more recently been shown to be associated with specific class I and/or II human leukocyte antigen (HLA) alleles. Abacavir-induced hypersensitivity
Imir G Metushi   +15 more
doaj   +1 more source

Omeprazole Increases the Efficacy of Acyclovir Against Herpes Simplex Virus Type 1 and 2

open access: yesFrontiers in Microbiology, 2019
Omeprazole was shown to improve the anti-cancer effects of the nucleoside analogue 5-fluorouracil. Here, we combined omeprazole with the antiviral nucleoside analogues ribavirin and acyclovir.
Martin Michaelis   +5 more
doaj   +1 more source

Acyclovir-induced neurotoxicity with a positive cerebrospinal fluid varicella zoster PCR result creating a management dilemma: a case report

open access: yesJournal of Medical Case Reports, 2020
Background Varicella zoster virus central nervous system infections can present as aseptic meningitis, encephalitis, myelitis, and vasculopathy.
Kelli M. Robertson   +2 more
doaj   +1 more source

Pharmacokinetics and analytical determination of acyclovir in Asian elephant calves (Elephas maximus)

open access: yesVeterinary and Animal Science, 2022
A therapeutic regimen that includes antiviral drugs is critical for the survival of Asian elephant (Elephas maximus) calves infected with elephant endotheliotropic herpesvirus hemorrhagic disease (EEHV-HD), with acyclovir showing considerable promise ...
Siripat Khammesri   +6 more
doaj   +1 more source

FLUOROMETRIC•DETERMINATION OF ACYCLOVIR IN SPIKED HUMAN PLASMA [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1993
A highly sensitive fluorometric method for determination of acyclovir  is described. The method depends  on the interaction between acyclovir .and 7-hydroxy-4-methylcoumarin where a fluorophore of high fluorogenic activity is formed which has wavelengths
M. Mabrouk, A. Habeeb
doaj   +1 more source

Acyclovir-Loaded Chitosan Nanospheres from Nano-Emulsion Templating for the Topical Treatment of Herpesviruses Infections

open access: yesPharmaceutics, 2018
Acyclovir is not a good candidate for passive permeation since its polarity and solubility limit is partitioning into the stratum corneum. This work aims to develop a new topical formulation for the acyclovir delivery.
Manuela Donalisio   +6 more
doaj   +1 more source

Bullous eruptions in a preschool child: A rare adverse effect of acyclovir

open access: yesIndian Journal of Paediatric Dermatology, 2020
Acyclovir in children is usually associated with minimal local adverse effects, with bullous eruptions being extremely rare in occurrence. A 5-year-old boy was admitted to the pediatric intensive care unit as a case of febrile encephalopathy with status ...
Nidhi Garg, K V Vinu Balraam
doaj   +1 more source

Effects of Acyclovir on the Cerebellar Cortex of Adult Male Albino Rats And The Protective Effect Of Zinc Sulfate (Histological and Immunohistochemical Study)

open access: yesSVU - International Journal of Medical Sciences
Background: Acyclovir is an antiviral drug. for the treatment of systemic herpes infections and central nervous system infections. Zinc is a vital mineral that found in foods and consumed as a dietary supplement.
Asmaa Sabry Bassit   +2 more
doaj   +1 more source

Therapeutic effects of acyclovir and acyclovir-clobetasol nanofibers vs. cream formulation for recurrent herpes labialis

open access: yesBMC Oral Health
Objectives This study aims to compare the therapeutic effects of acyclovir nanofiber and acyclovir-clobetasol nanofiber formulations with their non-nano formulations (cream formulation) on recurrent labial herpes.
Shahla Mirzaei   +4 more
doaj   +1 more source

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