Results 41 to 50 of about 6,940 (174)

Acyl homoserine lactone-based quorum sensing in a methanogenic archaeon [PDF]

The ISME Journal, 2012
Abstract Acyl homoserine lactone (AHL)-based quorum sensing commonly refers to cell density-dependent regulatory mechanisms found in bacteria. However, beyond bacteria, this cell-to-cell communication mechanism is poorly understood. Here we show that a methanogenic archaeon, Methanosaeta harundinacea 6Ac, encodes an active quorum sensing
Guishan, Zhang, Fan, Zhang, Gang, Ding, Jie, Li, Xiaopeng, Guo, Jinxing, Zhu, Liguang, Zhou, Shichun, Cai, Xiaoli, Liu, Yuanming, Luo, Guifeng, Zhang, Wenyuan, Shi, Xiuzhu, Dong   +12 more
openaire   +2 more sources

Quorum Quenching in a Novel Acinetobacter sp. XN-10 Bacterial Strain against Pectobacterium carotovorum subsp. carotovorum

Microorganisms, 2020
Quorum sensing (QS) is a cell density-dependent mechanism that regulates the expression of specific genes in microbial cells. Quorum quenching (QQ) is a promising strategy for attenuating pathogenicity by interfering with the QS system of pathogens.
Wenping Zhang, Qingqing Luo, Yiyin Zhang, Xinghui Fan, Tian Ye, Sandhya Mishra, Pankaj Bhatt, Lianhui Zhang, Shaohua Chen   +8 more
doaj   +1 more source

A Rhodococcal Transcriptional Regulatory Mechanism Detects the Common Lactone Ring of AHL Quorum-Sensing Signals and Triggers the Quorum-Quenching Response

Frontiers in Microbiology, 2018
The biocontrol agent Rhodococcus erythropolis disrupts virulence of plant and human Gram-negative pathogens by catabolizing their N-acyl-homoserine lactones.
Corinne Barbey, Corinne Barbey, Corinne Barbey, Corinne Barbey, Andrea Chane, Andrea Chane, Jean-François Burini, Jean-François Burini, Olivier Maillot, Olivier Maillot, Annabelle Merieau, Annabelle Merieau, Mathias Gallique, Mathias Gallique, Amélie Beury-Cirou, Amélie Beury-Cirou, Amélie Beury-Cirou, Yoan Konto-Ghiorghi, Yoan Konto-Ghiorghi, Marc Feuilloley, Marc Feuilloley, Virginie Gobert, Virginie Gobert, Virginie Gobert, Xavier Latour, Xavier Latour   +25 more
doaj   +1 more source

Specificity of Acyl-Homoserine Lactone Synthases Examined by Mass Spectrometry [PDF]

Journal of Bacteriology, 2006
ABSTRACT Many gram-negative bacteria produce a specific set of N -acyl- l -homoserine-lactone (AHL) signaling molecules for the purpose of quorum sensing, which is a means of regulating coordinated gene expression in a cell-density-dependent manner.
Ty A, Gould, Jake, Herman, Jessica, Krank, Robert C, Murphy, Mair E A, Churchill   +4 more
openaire   +2 more sources

A novel metagenomic short-chain dehydrogenase/reductase attenuates Pseudomonas aeruginosa biofilm formation and virulence on Caenorhabditis elegans. [PDF]

PLoS ONE, 2011
In Pseudomonas aeruginosa, the expression of a number of virulence factors, as well as biofilm formation, are controlled by quorum sensing (QS). N-Acylhomoserine lactones (AHLs) are an important class of signaling molecules involved in bacterial QS and ...
Patrick Bijtenhoorn, Hubert Mayerhofer, Jochen Müller-Dieckmann, Christian Utpatel, Christina Schipper, Claudia Hornung, Matthias Szesny, Stephanie Grond, Andrea Thürmer, Elzbieta Brzuszkiewicz, Rolf Daniel, Katja Dierking, Hinrich Schulenburg, Wolfgang R Streit   +13 more
doaj   +1 more source

A New Acyl-homoserine Lactone Molecule Generated by Nitrobacter winogradskyi [PDF]

Scientific Reports, 2016
AbstractIt is crucial to reveal the regulatory mechanism of nitrification to understand nitrogen conversion in agricultural systems and wastewater treatment. In this study, the nwiI gene of Nitrobacter winogradskyi was confirmed to be a homoserine lactone synthase by heterologous expression in Escherichia coli that synthesized several acyl-homoserine ...
Shen, Qiuxuan, Gao, Jie, Liu, Jun, Liu, Shuangjiang, Liu, Zijun, Wang, Yinghuan, Guo, Baoyuan, Zhuang, Xuliang, Zhuang, Guoqiang   +8 more
openaire   +3 more sources

Exploration of the Quorum-Quenching Mechanism in Pseudomonas nitroreducens W-7 and Its Potential to Attenuate the Virulence of Dickeya zeae EC1

Frontiers in Microbiology, 2021
Quorum quenching (QQ) is a novel, promising strategy that opens up a new perspective for controlling quorum-sensing (QS)-mediated bacterial pathogens.
Wenping Zhang, Wenping Zhang, Xinghui Fan, Xinghui Fan, Jiayi Li, Jiayi Li, Tian Ye, Tian Ye, Sandhya Mishra, Sandhya Mishra, Lianhui Zhang, Lianhui Zhang, Shaohua Chen, Shaohua Chen   +13 more
doaj   +1 more source

A novel plasmid for detection of N-acyl homoserine lactones [PDF]

Plasmid, 2009
Many bacteria utilize acyl-homoserine lactones as cell to cell signals that can regulate the expression of numerous genes. Structural differences in acyl-homoserine lactones produced by different bacteria, such as acyl side chain length and the presence or absence of an oxy group, make many of the commonly used detection bioassays impractical for broad
Elizabeth A, Ling, Matthew L, Ellison, Everett C, Pesci   +2 more
openaire   +2 more sources

The Pseudomonas aeruginosa Orphan Quorum Sensing Signal Receptor QscR Regulates Global Quorum Sensing Gene Expression by Activating a Single Linked Operon

mBio, 2018
Pseudomonas aeruginosa uses two acyl-homoserine lactone signals and two quorum sensing (QS) transcription factors, LasR and RhlR, to activate dozens of genes.
Fengming Ding, Ken-Ichi Oinuma, Nicole E. Smalley, Amy L. Schaefer, Omar Hamwy, E. Peter Greenberg, Ajai A. Dandekar   +6 more
doaj   +1 more source

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source