Results 121 to 130 of about 106,658 (300)

Effects of detergents on activity, thermostability and aggregation of immobilized lipases [PDF]

open access: yes, 2014
Predmetom tejto diplomovej práce bolo štúdium vplyvu detergentov na aktivitu, termostabilitu a agregáciu voľnej a imobilizovanej formy komerčného preparátu lipázy izolovanej z mikroskopickej huby Rhizopus arrhizus. Teoretická časť obsahuje ucelenú rešerš
Bančáková, Anna
core  

Coexistence of Wolbachia with Buchnera aphidicola and a secondary symbiont in the aphid Cinara cedri.

open access: yes, 2004
Intracellular symbiosis is very common in the insect world. For the aphid Cinara cedri, we have identified by electron microscopy three symbiotic bacteria that can be characterized by their different sizes, morphologies, and electrodensities.
García-Verdugo, José Manuel   +6 more
core   +2 more sources

High-Throughput Screening of Acyl-CoA Thioesterase I Mutants Using a Fluid Array Platform [PDF]

open access: yes, 2019
Screening target microorganisms from a mutated recombinant library plays a crucial role in advancing synthetic biology and metabolic engineering. However, conventional screening tools have several limitations regarding throughput, cost, and labor.
Kim, Taesung   +5 more
core   +1 more source

High Sugar Induced RCC2 Lactylation Drives Breast Cancer Tumorigenicity Through Upregulating MAD2L1

open access: yesAdvanced Science, EarlyView.
This study finds that KAT2A mediates the lactylation modification of the non‐histone protein RCC2 at K124, facilitating the recruitment of free SERBP1 and aiding in the formation of the initial SERBP1‐MAD2L1 complex. SERBP1 enhances the stability of MAD2L1 mRNA and promotes cellular proliferation.
Bowen Zheng   +11 more
wiley   +1 more source

Dynamics of Hydrogen Bonds Coupling on the Specific DNA-Protein Interactions [PDF]

open access: yesarXiv, 2016
We propose a dynamical model depicting the interactions between DNA and a specific binding protein involving long range transmissions. The dynamics rely on the coupling between Hydrogen bonds formed between DNA and protein and between the base pairs because they account for site specificity of the binding.
arxiv  

Comparison of aldehyde-producing activities of cyanobacterial acyl-(acyl carrier protein) reductases [PDF]

open access: yes, 2016
Additional file 1: Table S1. Cyanobacterial AARs found by the BLAST search. The group number in the phylogenetic tree is shown in the first column. In each group, the cyanobacterial strains are listed in the same order as in Fig. 1.
Hisashi Kudo   +3 more
core   +2 more sources

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

open access: yesAdvanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang   +10 more
wiley   +1 more source

Dissecting how modular polyketide synthase ketoreductases interact with acyl carrier protein-attached substrates [PDF]

open access: yes, 2018
Interaction studies using fragments excised from the modular mycolactone polyketide synthase show that ketoreductase domains possess a generic binding site for acyl carrier protein domains and provide evidence that the pendant 5′-phosphopantetheine ...
Broadhurst, RW   +3 more
core   +1 more source

Glycolysis‐Derived Lactate Induces ACSL4 Expression and Lactylation to Activate Ferroptosis during Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
Glycolysis‐derived lactate activates nucleus pulposus cell ferroptosis via Histon H3K18la‐mediated ACSL4 transcription and ACSL4 lactylation and aggravate intervertebral disc degeneration. Inhibiting glycolysis via gene silencing or chemical intervention reduces the production of lactate and ameliorates ferroptosis activation and nucleus pulposus ...
Kaiqiang Sun   +10 more
wiley   +1 more source

A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage

open access: yesAngewandte Chemie, EarlyView.
This work advances methodology by addressing challenges in mimicking the complex in vivo spatial relationships of histone acetylation and DNA damage. The combination of an abiotic/enzymatic hybrid catalyst system (ABEHCS) and the plug‐and‐play method has constituted a versatile platform to construct nucleosome arrays with precise histone acetylation ...
Ziyun Liu   +6 more
wiley   +2 more sources

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