Results 51 to 60 of about 80,359 (315)

Crystal structure of Pseudomonas aeruginosa FabB C161A, a template for structure-based design for new antibiotics [version 2; peer review: 2 approved]

open access: yesF1000Research, 2022
Background: FabB (3-oxoacyl-[acyl-carrier-protein] synthase 1) is part of the fatty acid synthesis II pathway found in bacteria and a potential target for antibiotics.
Vladyslav Yadrykhins'ky   +2 more
doaj  

Enzymatic Desaturation of Stearyl Acyl Carrier Protein [PDF]

open access: yesJournal of Biological Chemistry, 1966
Abstract Stearyl acyl carrier protein, chemically prepared from 1-14C stearic acid and Escherichia coli acyl carrier protein, is desaturated to oleic acid by extracts of photoauxotrophic Euglena gracilis and of spinach. The soluble stearyl acyl carrier protein desaturase system from Euglena has been separated into three components, a reduced ...
Konrad Bloch, J. Nagai
openaire   +3 more sources

Genes of ACYL CARRIER PROTEIN Family Show Different Expression Profiles and Overexpression of ACYL CARRIER PROTEIN 5 Modulates Fatty Acid Composition and Enhances Salt Stress Tolerance in Arabidopsis

open access: yesFrontiers in Plant Science, 2017
Acyl carrier proteins (ACPs) are a group of small acidic proteins functioning as important cofactors in the de novo synthesis of fatty acids. In Arabidopsis, ACPs are encoded by a small gene family comprising five plastid members, AtACP1 to AtACP5, and ...
Jiexue Huang   +9 more
doaj   +1 more source

Differential Effects of the Hormonal and Copper Intrauterine Device on the Endometrial Transcriptome. [PDF]

open access: yes, 2020
The contraceptive effectiveness of intrauterine devices (IUDs) has been attributed in part to a foreign body reaction in the endometrium. We performed this study to better understand mechanisms of action of contraceptives of by studying their effects on ...
Averbach, Sarah   +6 more
core  

A rhodanine agent active against non-replicating intracellular Mycobacterium avium subspecies paratuberculosis. [PDF]

open access: yes, 2009
BACKGROUND: Antibiotic therapy targeting chronic mycobacterial disease is often ineffective due to problems with the emergence of drug resistance and non-replicating persistent intracellular antibiotic resistant phenotypes.
Bull, TJ   +3 more
core   +3 more sources

2-Acylglycerolphosphoethanolamine acyltransferase/acyl-acyl carrier protein synthetase is a membrane-associated acyl carrier protein binding protein

open access: yesJournal of Biological Chemistry, 1989
Two enzymatic activities, 2-acylglycerolphosphoethanolamine (2-acyl-GPE) acyltransferase and acyl-acyl carrier protein (acyl-ACP) synthetase, were solubilized and purified from Escherichia coli membranes. Electrophoretic analysis of the final product of the purification procedure revealed a single protein species with an apparent molecular mass of 27 ...
Li Hsu   +3 more
openaire   +3 more sources

Evolutionary significance of self‐acylation property in acyl carrier proteins [PDF]

open access: yesIUBMB Life, 2009
AbstractAcyl carrier protein is an integral component of many cellular metabolic processes. A number of studies have reported self‐acylation behavior in acyl carrier proteins. Although ACPs exhibit high levels of similarity in their primary and tertiary structures, self‐acylation behavior is restricted to only some ACPs that can be classified into two ...
Misra, Ashish   +2 more
openaire   +3 more sources

Biosynthesis of thiocarboxylic acid-containing natural products. [PDF]

open access: yes, 2018
Thiocarboxylic acid-containing natural products are rare and their biosynthesis and biological significance remain unknown. Thioplatensimycin (thioPTM) and thioplatencin (thioPTN), thiocarboxylic acid congeners of the antibacterial natural products ...
Deng, Youchao   +9 more
core   +1 more source

A Soybean Acyl Carrier Protein, GmACP, Is Important for Root Nodule Symbiosis

open access: yesMolecular Plant-Microbe Interactions, 2014
Legumes (members of family Fabaceae) establish a symbiotic relationship with nitrogen-fixing soil bacteria (rhizobia) to overcome nitrogen source limitation.
Jun Wang   +10 more
doaj   +1 more source

A Receptor Component of the Chloroplast Protein Translocation Machinery [PDF]

open access: yes, 1994
The chloroplast outer envelope protein OEP86 functions as a receptor in precursor protein translocation into chloroplasts. Sequence analysis suggests that the precursor of OEP86 is directed to the chloroplast outer envelope by a cleavable, negatively ...
Heemeyer, Frank   +4 more
core   +1 more source

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