Results 101 to 110 of about 101,485 (290)

Radiation inactivation analysis of acyl-CoA:retinol acyltransferase and lecithin:retinol acyltransferase in rat liver

open access: yesJournal of Lipid Research, 1993
Microsomes from liver and several other tissues esterify retinol through both fatty acyl-CoA-dependent and -independent reactions. Two activities, acyl-CoA:retinol acyltransferase (ARAT) and lecithin:retinol acyltransferase (LRAT) activities, have been characterized enzymatically but neither has yet been purified and characterized biochemically.
A C Ross, E S Kempner
openaire   +4 more sources

Synthetic Biology: A Bridge between Artificial and Natural Cells. [PDF]

open access: yes, 2014
Artificial cells are simple cell-like entities that possess certain properties of natural cells. In general, artificial cells are constructed using three parts: (1) biological membranes that serve as protective barriers, while allowing communication ...
Ding, Yunfeng, Tan, Cheemeng, Wu, Fan
core   +2 more sources

Mining the active proteome of Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2011
Assigning functions to the >30.000 proteins encoded by the Arabidopsis genome is a challenging task of the Arabidopsis Functional Genomics Network.
Renier A. L. Van Der Hoorn   +5 more
doaj   +1 more source

Effects of mitochondrial NADP+-dependent isocitrate dehydrogenase deficiency on fructose-induced obesity in mice [PDF]

open access: yes, 2018
Obesity prevalence in the United States continues to increase and is associated with health consequences such as type 2 diabetes, hypertension, atherosclerosis, and hyperlipidemia.
Beane, Kaleigh Elizabeth   +1 more
core   +2 more sources

In Vivo and in Vitro Evidence for Biochemical Coupling of Reactions Catalyzed by Lysophosphatidylcholine Acyltransferase and Diacylglycerol Acyltransferase*

open access: yesJournal of Biological Chemistry, 2015
Background: Plant polyunsaturated fatty acids (PUFAs) are mainly synthesized on phosphatidylcholine (PC). Results: Diacylglycerol acyltransferase (DGAT) produced higher amount of PUFA-containing TAG in the presence of acyl-CoA:lysophosphatidylcholine ...
Xue Pan   +6 more
semanticscholar   +1 more source

Associations between the K232A polymorphism in the diacylglycerol-O-transferase 1 (DGAT1) gene and performance in Irish Holstein-Friesian dairy cattle [PDF]

open access: yes, 2010
peer-reviewedSelection based on genetic polymorphisms requires accurate quantification of the effect or association of the polymorphisms with all traits of economic importance. The objective of this study was to estimate, using progeny performance data
Berry, Donagh   +5 more
core  

Proliferative glioblastoma cancer cells exhibit persisting temporal control of metabolism and display differential temporal drug susceptibility in chemotherapy [PDF]

open access: yes, 2019
Even in immortalized cell lines, circadian clocks regulate physiological processes in a time-dependent manner, driving transcriptional and metabolic rhythms, the latter being able to persist without transcription.
Gaveglio, Virginia Lucía   +6 more
core   +1 more source

Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.

open access: yesCancer Research, 2013
Porcupine (PORCN) is a membrane bound O-acyltransferase that is required for Wnt palmitoylation, secretion, and biologic activity. All evaluable human Wnts require PORCN for their activity, suggesting that inhibition of PORCN could be an effective ...
K. Proffitt   +7 more
semanticscholar   +1 more source

Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis.

open access: yesProceedings of the National Academy of Sciences of the United States of America, 1998
Triacylglycerols are quantitatively the most important storage form of energy for eukaryotic cells. Acyl CoA:diacylglycerol acyltransferase (DGAT, EC 2.3.1.20) catalyzes the terminal and only committed step in triacylglycerol synthesis, by using ...
S. Cases   +11 more
semanticscholar   +1 more source

A novel pathway for lipid biosynthesis: the direct acylation of glycerol

open access: yesJournal of Lipid Research, 2001
The acylation of glycerol-3-phosphate by acyl-CoA is regarded as the first committed step for the synthesis of the lipoidal moiety in glycerolipids. The direct acylation of glycerol in mammalian tissues has not been demonstrated.
Douglas P. Lee   +6 more
doaj  

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