Results 111 to 120 of about 86,883 (336)

Involvement of a putative acyltransferase gene in sporangium formation in Actinoplanes missouriensis

open access: yesMicrobiology Spectrum
The actinomycete Actinoplanes missouriensis forms branched substrate mycelia during vegetative growth and produces terminal sporangia, each of which contains a few hundred spherical flagellated spores, from the substrate mycelia through short ...
Shixuan Hu   +3 more
doaj   +1 more source

Acylation of sn-glycerol 3-phosphate by cell fractions of rat liver

open access: yesJournal of Lipid Research, 1968
The esterification of sn-glycerol 3-(dihydrogen phosphate) with long-chain fatty acids by rat liver microsomal preparations has been studied. A newly modified spectrophotometric assay for glycerolphosphate acyltransferase (GP-cyltransferase) compared ...
Harold J. Fallon, Robert G. Lamb
doaj   +1 more source

Modulation of PGC-1α activity as a treatment for metabolic and muscle-related diseases [PDF]

open access: yes, 2014
Physical inactivity is a predisposing factor for various disease states including obesity, cardiovascular disease, as well as for certain types of cancer. Regular endurance exercise mediates several beneficial effects such as increased energy expenditure
Handschin, Christoph   +1 more
core   +1 more source

Development of a Promising Bivalent Vaccine Against Klebsiella pneumoniae Based on Glycoengineered GMMA (geGMMA)

open access: yesExploration, EarlyView.
Multidrug‐resistant Klebsiella pneumoniae poses a significant threat as a nosocomial pathogen, with no current licensed vaccines available. This study used a mutant E. coli strain expressing exogenous polysaccharides (from K. pneumoniae) to establish glycoengineered generalized modules for membrane antigens (geGMMA) vaccine platform, which demonstrated
Jingqin Ye   +13 more
wiley   +1 more source

Production of human recombinant proapolipoprotein A-I in Escherichia coli: purification and biochemical characterization [PDF]

open access: yes, 1989
A human liver cDNA library was used to isolate a clone coding for apolipoprotein A-I (Apo A-I). The clone carries the sequence for the prepeptide (18 amino acids), the propeptide (6 amino acids), and the mature protein (243 amino acids).
Bollen, A.   +12 more
core   +1 more source

Revisiting Cholesterol‐Lowering Nutraceuticals and Functional Foods: Mechanistic Insights Into Cholesterol Homeostasis and Gut Microbiota

open access: yesFood Chemistry International, EarlyView.
Mechanistic Insights into Cholesterol Homeostasis and Gut Microbiota. ABSTRACT The gut microbiota acts as a crucial intermediary between diets and human health. The accumulating evidence suggests that gut microbiota may play a significant role in cholesterol metabolism.
Xiaoxuan Zhang   +4 more
wiley   +1 more source

Mining the active proteome of Arabidopsis thaliana

open access: yesFrontiers in Plant Science, 2011
Assigning functions to the >30.000 proteins encoded by the Arabidopsis genome is a challenging task of the Arabidopsis Functional Genomics Network.
Renier A. L. Van Der Hoorn   +5 more
doaj   +1 more source

Dysregulated Choline, Methionine, and Aromatic Amino Acid Metabolism in Patients with Wilson Disease: Exploratory Metabolomic Profiling and Implications for Hepatic and Neurologic Phenotypes. [PDF]

open access: yes, 2019
Wilson disease (WD) is a genetic copper overload condition characterized by hepatic and neuropsychiatric symptoms with a not well-understood pathogenesis.
Czlonkowska, Anna   +6 more
core   +2 more sources

Synergistic Regulation of Mammary Gland Ferroptosis by Vitamin E and Selenium Under Environmental Heat Stress

open access: yesFood Frontiers, EarlyView.
Sodium selenite or vitamin E supplementation enhances antioxidant defenses in mouse mammary glands, reducing oxidative stress, lipid peroxidation, and iron accumulation. This boosts GPX4 activity, inhibits PTGS2, and activates mTORC1, improving milk fat droplet formation and protein synthesis, with the combined treatment showing the greatest benefit ...
Qianzi Zhang   +7 more
wiley   +1 more source

Silencing AT3 gene reduces the expression of pAmt, BCAT, Kas, and Acl genes involved in capsaicinoid biosynthesis in chili pepper fruits

open access: yesBiologia Plantarum, 2015
The effects of AT3-gene silencing on the expression of genes involved in capsaicinoid biosynthesis was investigated in chili pepper (Capsicum annuum L.) cv. Tampiqueño 74 fruits.
M. L. Arce-Rodríguez, N. Ochoa-Alejo
doaj   +1 more source

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