Results 111 to 120 of about 63,314 (347)

Radiation inactivation analysis of acyl-CoA:retinol acyltransferase and lecithin:retinol acyltransferase in rat liver

Journal of Lipid Research, 1993
Microsomes from liver and several other tissues esterify retinol through both fatty acyl-CoA-dependent and -independent reactions. Two activities, acyl-CoA:retinol acyltransferase (ARAT) and lecithin:retinol acyltransferase (LRAT) activities, have been characterized enzymatically but neither has yet been purified and characterized biochemically.
A C Ross, E S Kempner
openaire   +4 more sources

Revealing the contribution of GbPR10.5D1 to resistance against Verticillium dahliae and its regulation for structural defense and immune signaling

The Plant Genome, Volume 15, Issue 4, December 2022., 2022
Abstract As an important family of pathogenesis‐related (PR) proteins, the functional diversification and roles of PR10s in biotic stress have been well documented. However, the molecular basis of PR10s in plant defense responses against pathogens remains to be further understood.
Jin Guo, Peihua Cao, Leitian Yuan, Guixian Xia, Huanyang Zhang, Jing Li, Fuxin Wang   +6 more
wiley   +1 more source

In Vivo and in Vitro Evidence for Biochemical Coupling of Reactions Catalyzed by Lysophosphatidylcholine Acyltransferase and Diacylglycerol Acyltransferase*

Journal of Biological Chemistry, 2015
Background: Plant polyunsaturated fatty acids (PUFAs) are mainly synthesized on phosphatidylcholine (PC). Results: Diacylglycerol acyltransferase (DGAT) produced higher amount of PUFA-containing TAG in the presence of acyl-CoA:lysophosphatidylcholine ...
Xue Pan, Guanqun Chen, M. Kazachkov, M. Greer, K. M. Caldo, Jitao Zou, R. Weselake   +6 more
semanticscholar   +1 more source

Nanomaterials for enhanced X‐ray‐triggered cancer therapy: Progress and prospects

BMEMat, EarlyView.
This review summarizes the latest progress in nanomaterials for X‐ray‐triggered cancer therapy, highlighting their various advantages such as targeted delivery, reduced side effects, and enhanced therapeutic efficacy. Abstract X‐rays, a form of ionizing radiation with high energy and significant penetration capability, are commonly used in clinical ...
Yuanchun Chen, Shijie Shangguan, Zhongyu Lin, Xuemei Zeng, Siew Yin Chan, Xian Qin, Shuangqian Yan   +6 more
wiley   +1 more source

Alcohol‐free and low‐alcohol beers: Aroma chemistry and sensory characteristics

Comprehensive Reviews in Food Science and Food Safety, Volume 22, Issue 1, Page 233-259, January 2023., 2023
Abstract Alcohol‐free beers have gained popularity in the last few decades because they provide a healthier alternative to alcoholic beers and can be more widely consumed. Consumers are becoming more aware of the benefits of reducing their alcohol consumption, and this has increased the sales of nonalcoholic alternatives.
José A. Piornos, Elisabeth Koussissi, Dimitrios P. Balagiannis, Eric Brouwer, Jane K. Parker   +4 more
wiley   +1 more source

Pharmacological inhibition of the Wnt acyltransferase PORCN prevents growth of WNT-driven mammary cancer.

Cancer Research, 2013
Porcupine (PORCN) is a membrane bound O-acyltransferase that is required for Wnt palmitoylation, secretion, and biologic activity. All evaluable human Wnts require PORCN for their activity, suggesting that inhibition of PORCN could be an effective ...
K. Proffitt, B. Madan, Zhiyuan Ke, V. Pendharkar, L. Ding, M. Lee, R. Hannoush, D. Virshup   +7 more
semanticscholar   +1 more source

Identification of a gene encoding an acyl CoA:diacylglycerol acyltransferase, a key enzyme in triacylglycerol synthesis.

Proceedings of the National Academy of Sciences of the United States of America, 1998
Triacylglycerols are quantitatively the most important storage form of energy for eukaryotic cells. Acyl CoA:diacylglycerol acyltransferase (DGAT, EC 2.3.1.20) catalyzes the terminal and only committed step in triacylglycerol synthesis, by using ...
S. Cases, S. J. Smith, Y. Zheng, H. M. Myers, S. Lear, E. Sande, S. Novak, C. Collins, C. Welch, A. J. Lusis, S. Erickson, Robert V Farese   +11 more
semanticscholar   +1 more source

Copper in cancer: friend or foe? Metabolism, dysregulation, and therapeutic opportunities

Cancer Communications, EarlyView.
Abstract Copper, one of the essential nutrients for the human body, acts as an electron relay in multiple pathways due to its redox properties. Both deficiencies and excesses of copper lead to cellular fragility. Therefore, it can manifest pro‐ and anti‐cancer properties in tumors. Therefore, it is crucial to clarify the copper activity within the cell.
Dan Shan, Jinling Song, Yuqing Ren, Yuyuan Zhang, Yuhao Ba, Peng Luo, Quan Cheng, Hui Xu, Siyuan Weng, Anning Zuo, Shutong Liu, Xinwei Han, Jinhai Deng, Zaoqu Liu   +13 more
wiley   +1 more source

GPCR signaling regulates severe stress‐induced organismic death in Caenorhabditis elegans

Aging Cell, Volume 22, Issue 1, January 2023., 2023
C. elegans rapidly dies upon the exposure to severe freezing‐thaw stress in a regulated fashion (stress‐induced phenoptosis). Signaling from G‐protein‐coupled receptor FSHR‐1 promotes stress‐induced gene expression and phenoptosis. Findings are of implications to the evolutionary kin selection theory and the disposable soma hypothesis of aging ...
Changnan Wang, Yong Long, Bingying Wang, Chao Zhang, Dengke K. Ma   +4 more
wiley   +1 more source

A novel pathway for lipid biosynthesis: the direct acylation of glycerol

Journal of Lipid Research, 2001
The acylation of glycerol-3-phosphate by acyl-CoA is regarded as the first committed step for the synthesis of the lipoidal moiety in glycerolipids. The direct acylation of glycerol in mammalian tissues has not been demonstrated.
Douglas P. Lee, Andrew S. Deonarine, Martin Kienetz, Quansheng Zhu, Monika Skrzypczak, Monroe Chan, Patrick C. Choy   +6 more
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