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Alcohol acyltransferases for the biosynthesis of esters
Esters are widely used in food, energy, spices, chemical industry, etc., becoming an indispensable part of life. However, their production heavily relies on the fossil energy industry, which presents significant challenges associated with energy ...
Gaofei Liu, Lei Huang, Jiazhang Lian
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Phenolamides represent one of the largest classes of plant-specialized secondary metabolites and function in diverse physiological processes, including defense responses and development.
Chengyuan Wang+6 more
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Substrate recruitment by zDHHC protein acyltransferases
Protein palmitoylation is the post-translational attachment of fatty acids, most commonly palmitate (C16 : 0), onto a cysteine residue of a protein. This reaction is catalysed by a family of integral membrane proteins, the zDHHC protein acyltransferases (
Martin Ian P. Malgapo, Maurine E. Linder
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Glycerophosphate/Acylglycerophosphate Acyltransferases [PDF]
Acyl-CoA:glycerol-3-phosphate acyltransferase (GPAT) and acyl-CoA: 1-acyl-glycerol-3-phosphate acyltransferase (AGPAT) are involved in the de novo synthesis of triacylglycerol (TAG) and glycerophospholipids.
Atsushi Yamashita+6 more
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Molecular functional mechanisms of two alcohol acetyltransferases in Lavandula x intermedia (lavandin) [PDF]
Volatile esters are key flavor components in most plants, including Lavandula x intermedia (lavandin). The final step in ester biosynthesis is catalyzed by Lavandula x intermedia alcohol acyltransferases (LiAATases), which attach alcohols to acyl groups.
Dafeng Liu+8 more
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Steryl esters (SEs) serve as a storage pool of sterols that helps to maintain proper levels of free sterols (FSs) in cell membranes throughout plant growth and development, and participates in the recycling of FSs and fatty acids released from cell ...
Juan A. Lara+12 more
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Acyltransferases as Tools for Polyketide Synthase Engineering
Polyketides belong to the most valuable natural products, including diverse bioactive compounds, such as antibiotics, anticancer drugs, antifungal agents, immunosuppressants and others.
Ewa Maria Musiol-Kroll+1 more
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Specificity of acyl-CoA:phospholipid acyltransferases: solvent and temperature effects
Acyltransfer from CoA thiol esters to either the 1- or 2-position of monoacylglycerophosphoryl choline, which is catalyzed by a microsomal preparation from rat liver, had a temperature optimum of 30-35°C.
Peter Jezyk, William E.M. Lands
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Palmitoylation landscapes across human cancers reveal a role of palmitoylation in tumorigenesis [PDF]
Background Protein palmitoylation, which is catalyzed by palmitoyl-transferase and de-palmitoyl-transferase, plays a crucial role in various biological processes. However, the landscape and dynamics of protein palmitoylation in human cancers are not well
Yue Kong+8 more
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Lactylation in cancer: metabolic mechanism and therapeutic strategies [PDF]
Recent progress in cancer metabolism research has identified lactylation as a critical post-translational modification influencing tumor development and progression.
Ying Sui+4 more
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