Characterization of two
Background Two previously uncharacterized Arabidopsis genes that encode proteins with acyltransferase PlsC regions were selected for study based on their sequence similarity to a recently identified lung lysophosphatidylcholine acyltransferase (LPCAT ...
Stymne Sten +3 more
doaj +4 more sources
Identification and Characterization of Sterol Acyltransferases Responsible for Steryl Ester Biosynthesis in Tomato [PDF]
Steryl esters (SEs) serve as a storage pool of sterols that helps to maintain proper levels of free sterols (FSs) in cell membranes throughout plant growth and development, and participates in the recycling of FSs and fatty acids released from cell ...
Juan A. Lara +12 more
doaj +3 more sources
Recent Insights and Future Perspectives on Promiscuous Hydrolases/Acyltransferases [PDF]
Promiscuous hydrolases/acyltransferases have attracted attention for their ability to efficiently catalyze selective transacylation reactions in water to produce esters, thioesters, amides, carbonates, and carbamates.
Badenhorst, Christoffel P. S. +9 more
core +1 more source
Efficient Acylation of Sugars and Oligosaccharides in Aqueous Environment Using Engineered Acyltransferases [PDF]
A major challenge for the enzymatic synthesis of sugar esters is the low solubility of sugars in anhydrous, often toxic, organic solvents. We overcame this limitation by using acyltransferases for efficient acetylation of sugars in water.
Mihovilovic, Marko D.; orcid: +6 more
core +1 more source
Intestinal triacylglycerol synthesis in fat absorption and systemic energy metabolism
The intestine plays a prominent role in the biosynthesis of triacylglycerol (triglyceride; TAG). Digested dietary TAG is repackaged in the intestine to form the hydrophobic core of chylomicrons, which deliver metabolic fuels, essential fatty acids, and ...
Chi-Liang Eric Yen +2 more
doaj +1 more source
Characterisation of two alcohol acyltransferases from kiwifruit (Actinidia spp.) reveals distinct substrate preferences. [PDF]
Volatile esters are key compounds of kiwifruit flavour and are formed by alcohol acyltransferases that belong to the BAHD acyltransferase superfamily.
Souleyre, Edwige J. F. +13 more
core +1 more source
Acyl-CoA:Lysophospholipid Acyltransferases [PDF]
Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
Hideo, Shindou, Takao, Shimizu
openaire +2 more sources
MOGAT2: A New Therapeutic Target for Metabolic Syndrome
Metabolic syndrome is an ever-increasing health problem among the world’s population. It is a group of intertwined maladies that includes obesity, hypertriglyceridemia, hypertension, nonalcoholic fatty liver disease (NAFLD), and diabetes mellitus type II
Muhua Yang, Joseph T. Nickels
doaj +1 more source
Acyltransferases as Tools for Polyketide Synthase Engineering
Polyketides belong to the most valuable natural products, including diverse bioactive compounds, such as antibiotics, anticancer drugs, antifungal agents, immunosuppressants and others.
Ewa Maria Musiol-Kroll +1 more
doaj +1 more source
Approaches for manipulating individual organelles are important for learning more about their functions. Here the authors report a tool utilising phospholipase A/acyltransferases (PLAATs) for rapid defunctionalisation of organelles through remodelling of
Satoshi Watanabe +6 more
doaj +1 more source

