Results 241 to 250 of about 32,557 (330)

Crosstalk Between Ferroptosis and Cuproptosis in Intervertebral Disc Degeneration: Mechanisms, Therapeutic Targets, and Future Directions

open access: yesJOR SPINE, Volume 8, Issue 2, June 2025.
GSH, oxidative stress, TCA cycle, autophagy, and copper are the intersection targets of ferroptosis and cuproptosis in IVDD. ABSTRACT Background Intervertebral disc degeneration (IVDD) is a prevalent degenerative disease, with low back pain as its primary clinical symptom, imposing significant burdens on individuals and society.
Zhongpan Li   +4 more
wiley   +1 more source

Rat liver dihydroxyacetone-phosphate acyltransferases and their contribution to glycerolipid synthesis.

open access: hybrid, 1984
Peter Declercq   +5 more
openalex   +1 more source

SOAT1 Activates NLRP3 Inflammasome to Promote Cancer‐Related Lymphangiogenesis and Metastasis via IL‐1β/IL‐1R‐1 Axis in Oral Squamous Cell Carcinoma

open access: yesMolecular Carcinogenesis, Volume 64, Issue 6, Page 1039-1056, June 2025.
ABSTRACT Oral squamous cell carcinoma (OSCC) is a prevalent type of cancer in the head and neck region, significantly impacting patient survival rates and quality of life. Lymph node (LN) metastasis is a lead contributor to the poor prognosis associated with OSCC.
Chengzhi Zhao   +6 more
wiley   +1 more source

Subcellular localization of retinoids, retinoid-binding proteins, and acyl-CoA:retinol acyltransferase in rat liver

open access: hybrid, 1987
Earl H. Harrison   +3 more
openalex   +1 more source

Lactylation: From Homeostasis to Pathological Implications and Therapeutic Strategies

open access: yesMedComm, Volume 6, Issue 6, June 2025.
Lactylation, a novel post‐translational modification derived from lactate metabolism, plays a critical role in cellular homeostasis and disease pathogenesis. Under physiological conditions, lactylation regulates gene expression, immune responses, and metabolic adaptation. However, dysregulated lactylation is implicated in various pathological processes,
Xi Chen   +6 more
wiley   +1 more source

Lecithin:cholesterol acyltransferase. Functional regions and a structural model of the enzyme.

open access: hybrid, 1987
C.Y. Yang   +6 more
openalex   +1 more source

Role and Mechanisms of the mTOR Signalling Pathway in the Synthesis of Milk Components

open access: yesModern Agriculture, Volume 3, Issue 1, June 2025.
The regulatory network system of mTOR regulates lactose, milk fat, and milk protein. Milk is urgently needed for the strong development of the dairy industry to meet the growing demand and ensure that the nutritional needs of the world's population are met.
RongNuo Li   +3 more
wiley   +1 more source

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