Results 21 to 30 of about 32,557 (330)
Plant Physiology, 2020 One BAHD acyltransferase specifically mediates the acylation of shikonin, whereas a second BAHD acyltransferase acylates only alkannin, an enantiomer of shikonin, in Lithospermum erythrorhizon.
Haruka Oshikiri +4 more
semanticscholar +2 more sources
Acyl-CoA:Lysophospholipid Acyltransferases [PDF]
Journal of Biological Chemistry, 2009 Cell membranes contain several classes of glycerophospholipids, which have numerous structural and functional roles in the cells. Polyunsaturated fatty acids, including arachidonic acid and eicosapentaenoic acid, are located at the sn-2 (but not sn-1)-position of glycerophospholipids in an asymmetrical manner.
Hideo Shindou, Takao Shimizu
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Structural Basis for the Acyltransferase Activity of Lecithin:Retinol Acyltransferase-like Proteins [PDF]
Journal of Biological Chemistry, 2012 Lecithin:retinol acyltransferase-like proteins, also referred to as HRAS-like tumor suppressors, comprise a vertebrate subfamily of papain-like or NlpC/P60 thiol proteases that function as phospholipid-metabolizing enzymes. HRAS-like tumor suppressor 3, a representative member of this group, plays a key role in regulating triglyceride accumulation and ...
Krzysztof Palczewski +5 more
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Regulation of T cell function by protein S-acylation
Frontiers in Physiology, 2022 S-acylation, the reversible lipidation of free cysteine residues with long-chain fatty acids, is a highly dynamic post-translational protein modification that has recently emerged as an important regulator of the T cell function. The reversible nature of
Savannah J. West +4 more
doaj +1 more source
Local and substrate-specific S-palmitoylation determines subcellular localization of Gαo
Nature Communications, 2022 How palmitoylated proteins specifically localize is not fully understood. Here, authors created the SwissKASH assay to visualize S-palmitoylation in cells and uncovered a striking substrate selectivity of acyltransferases at the core of this process.
Gonzalo P. Solis +6 more
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Nature Communications, 2022 Approaches for manipulating individual organelles are important for learning more about their functions. Here the authors report a tool utilising phospholipase A/acyltransferases (PLAATs) for rapid defunctionalisation of organelles through remodelling of
Satoshi Watanabe +6 more
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Marine Drugs, 2013 The importance of n-3 long chain polyunsaturated fatty acids (LC-PUFAs) for human health has received more focus the last decades, and the global consumption of n-3 LC-PUFA has increased.
Alice Mühlroth +7 more
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Acyltransferases in Protease’s Clothing [PDF]
The Plant Cell, 2000 One of the most intriguing questions in plant secondary metabolism concerns the evolution of the genes required for the rapid diversification of plant chemistry. In particular, the mechanisms are beginning to be understood by which evolution recruits primary and intermediary metabolism genes ...
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MOGAT2: A New Therapeutic Target for Metabolic Syndrome
Diseases, 2015 Metabolic syndrome is an ever-increasing health problem among the world’s population. It is a group of intertwined maladies that includes obesity, hypertriglyceridemia, hypertension, nonalcoholic fatty liver disease (NAFLD), and diabetes mellitus type II
Muhua Yang, Joseph T. Nickels
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Planta, 2020 The main source of polyunsaturated acyl-CoA in cytoplasmic acyl-CoA pool of Camelina sativa seeds are fatty acids derived from phosphatidylcholine followed by phosphatidic acid. Contribution of phosphatidylethanolamine is negligible.
S. Klińska +3 more
semanticscholar +1 more source