Results 31 to 40 of about 32,557 (330)
Identification and characterization of piperine synthase from black pepper, Piper nigrum L.
Communications Biology, 2021 Schnabel et al. identify and characterize piperine synthase in developing black pepper fruits which catalyses the formation of piperine from piperoyl coenzyme A and piperidine.
Arianne Schnabel +5 more
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The structural basis for the phospholipid remodeling by lysophosphatidylcholine acyltransferase 3
Nature Communications, 2021 During phosphatidylcholine (PC) remodeling re-acylation is catalyzed by lysophosphatidylcholine acyltransferases (LPCAT). Here, the authors present crystal and cryo-EM structures of chicken LPCAT3 in the apo-, acyl donor-bound and acyl receptor-bound ...
Qing Zhang +14 more
doaj +1 more source
S-acylation of P2K1 mediates extracellular ATP-induced immune signaling in Arabidopsis
Nature Communications, 2021 S-acylation is a reversible protein post-translational modification that often regulates protein function at the plasma membrane. Here the authors show that an Arabidopsis extracellular ATP receptor P2K1 mediates phosphorylation of two S-acyltransferases
Dongqin Chen +5 more
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Versatility in acyltransferase activity completes chicoric acid biosynthesis in purple coneflower
Nature Communications, 2021 Biosynthetic pathway of chicoric acid in purple coneflower has not been fully elucidated, though the compound has been shown to have potential health benefits.
Rao Fu +7 more
doaj +1 more source
Microorganisms, 2021 Biocatalytic transesterification is commonly carried out employing lipases in anhydrous organic solvents since hydrolases usually prefer hydrolysis over acyl transfer in bulk water.
Amanda Staudt +7 more
doaj +1 more source
Discovery and Design of Family VIII Carboxylesterases as Highly Efficient Acyltransferases
Angewandte Chemie (International Ed. in English), 2020 Promiscuous acyltransferase activity is the ability of certain hydrolases to preferentially catalyze acyl transfer over hydrolysis, even in bulk water. However, poor enantioselectivity, low transfer efficiency, significant product hydrolysis, and limited
H. Müller +7 more
semanticscholar +1 more source
Nature Communications, 2021 AGPATs (1-acylglycerol-3-phosphate O-acyltransferases) catalyze the acylation of lysophosphatidic acid to form phosphatidic acid (PA), a key step in the synthesis of all glycerolipids.
Hoi Yin Mak +17 more
doaj +1 more source
In Vitro Analysis of Hedgehog Acyltransferase and Porcupine Fatty Acyltransferase Activities [PDF]
, 2019 Hedgehog and Wnt proteins are modified by covalent attachment of the fatty acids palmitate and palmitoleate, respectively. These lipid modifications are essential for Hedgehog and Wnt protein signaling activities and are catalyzed by related, but distinct fatty acyltransferases: Hedgehog acyltransferase (Hedgehog) and Porcupine (Wnt).
James J. Asciolla +4 more
openaire +2 more sources
BMC Plant Biology, 2009 Background Two previously uncharacterized Arabidopsis genes that encode proteins with acyltransferase PlsC regions were selected for study based on their sequence similarity to a recently identified lung lysophosphatidylcholine acyltransferase (LPCAT ...
Stymne Sten +3 more
doaj +1 more source
Membrane Topology of Hedgehog Acyltransferase [PDF]
Journal of Biological Chemistry, 2015 Hedgehog acyltransferase (Hhat) is a multipass transmembrane enzyme that mediates the covalent attachment of the 16-carbon fatty acid palmitate to the N-terminal cysteine of Sonic Hedgehog (Shh). Palmitoylation of Shh by Hhat is critical for short and long range signaling.
Armine Matevossian, Marilyn D. Resh
openaire +2 more sources